A5082726455- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Viral Infections and Vectors
- Insect and Pesticide Research
- Dermatological diseases and infestations
- Insect Pest Control Strategies
- Leptospirosis research and findings
- Vector-borne infectious diseases
- Vector-Borne Animal Diseases
- Forensic Entomology and Diptera Studies
- Mosquito-borne diseases and control
- Toxin Mechanisms and Immunotoxins
- Parasitic Infections and Diagnostics
- Brucella: diagnosis, epidemiology, treatment
- Insect behavior and control techniques
- Zoonotic diseases and public health
- Entomological Studies and Ecology
- Diptera species taxonomy and behavior
- Parasites and Host Interactions
- Allergic Rhinitis and Sensitization
- Burkholderia infections and melioidosis
- Coccidia and coccidiosis research
- Malaria Research and Control
- Study of Mite Species
- Insect symbiosis and bacterial influences
Ege University
2016-2025
Akdeniz University
2017-2023
Ege Üniversitesi Tıp Fakültesi Hastanesi
2023
Universidad de Murcia
2021
Universidade Nova de Lisboa
2021
Hebrew University of Jerusalem
2021
Instituto Ramón y Cajal de Investigación Sanitaria
2021
World Health Organization Regional Office for Europe
2021
European Food Safety Authority
2021
Organisation Mondiale de la Santé Animale
2021
Background The recent geographical expansion of phlebotomine vectors Leishmania infantum in the Mediterranean subregion has been attributed to ongoing climate changes. At these latitudes, activity sand flies is typically seasonal; because seasonal phenomena are also sensitive general variations climate, current phenological data sets can provide a baseline for continuing investigations on fly population dynamics that may impact future scenarios leishmaniasis transmission. With this aim,...
Background The determination of the acceptance COVID-19 vaccine by health personnel will also be a guide for upcoming vaccination studies. aim this study is to determine status amongst healthcare professionals. Materials and methods A total 1138 workers participated in cross-sectional between 17th 20th September, 2020. questionnaire, which was delivered via social media, filled out participants over "Google Forms." Results As result 68.6% professionals stated that they could vaccinated. Men,...
Human visceral leishmaniasis (VL) caused by L. infantum and cutaneous (CL) tropica have been reported in Turkey. is also responsible for canine (CanL) it widely common the country. The main aim of present study was to design a real-time PCR method based on internal transcribed spacer 1 (ITS1) region diagnosis all clinical forms Mediterranean, identify species directly from samples. Totally, 315 specimens, human/canine (blood, bone marrow, lymph node) (lesion aspiration) samples, 51 Turkish...
Sand fly saliva plays an important role in Leishmania transmission. We characterized the host antibody response to from 3 sand species. Specific IgG was observed sera experimentally bitten mice as well individuals living endemic area of tropica Sanliurfa, Turkey. Sera Sanliurfa inhabitants showed high levels against Phlebotomus sergenti and P. papatasi, 2 most abundant species this area, but did not react with New World fly, Lutzomyia longipalpis. Patients active Le. lesions possessed...
A questionnaire survey of animal and human health authorities in Europe revealed that leishmaniases are not notifiable all countries with autochthonous cases. Few implement surveillance control targeting both infections. Leishmaniases considered emergent diseases most countries, lack resources is a challenge for control.
Infantile Mediterranean visceral leishmaniasis (IVL) and anthroponotic cutaneous (ACL) have long been known to exist in the western southeastern Turkey, respectively. To further study these other related diseases, a recombinant antigen (rK39) specific VL was used an ELISA for serodiagnosis of selected patients screening dog reservoir populations several endemic sites. Among 24 confirmed cases from rK39 proved be more sensitive than combination cultivation microscopy bone marrow aspirates....
ABSTRACT Currently available methods for the diagnosis of cutaneous leishmaniasis (CL) have low sensitivities or are unable to quantify number viable parasites. This constitutes a major obstacle disease and study effectiveness treatment schedules urges development improved detection methods. In this study, quantitative nucleic acid sequence-based amplification (QT-NASBA) technology was used detect Leishmania parasites in skin biopsy samples from CL patients. The assay is based on small...
The two Old World genera, Phlebotomus and Sergentomyia, were both recorded in southern Anatolia Turkey. species predominated comprised about 93% of the entire collection (3, 172 specimens). Out sixteen identified, belonged to genus Sergentomyia: S. dentata theodori. remaining fourteen grouped under four subgenera including some that are elsewhere known act as vectors human cutaneous leishmaniasis. Most P. tobbi (32.5%), but papatasi, transcaucasicus, halepensis, galilaeus, sergenti,...
Cutaneous leishmaniasis (CL) is a vector-born parasitic disease characterized by various skin lesions that cause disfiguration if healed spontaneously. Although CL has been endemic for many years in the southern regions of Turkey, an increasing incidence nonendemic being observed due to returning travelers and, more recently, Syrian refugees. Thus far, limited number national guidelines have proposed, but no common Turkish consensus emerged.The aim this study was develop diagnostic and...
ABSTRACT A new phlebovirus, Adana virus, was isolated from a pool of Phlebotomus spp. ( Diptera ; Psychodidae ) in the province Adana, Mediterranean region Turkey. Genetic analysis based on complete coding genomic sequences indicated that virus belongs to Salehabad species genus Phlebovirus family Bunyaviridae . is third for which sequence has been determined. To understand epidemiology seroprevalence study using microneutralization assay performed detect presence specific antibodies human...
Phlebotomine sandflies are vectors of a large variety arboviruses, mostly in the genus Phlebovirus. Many were discovered during last decade, but only partially sequenced because extremely high genetic diversity. Next-Generation sequencing (NGS) is key tool to achieve rapid these viruses. Here we present results obtained with custom-made automated platform for throughput processing (HTP) field-trapped sandflies. The aim an integrated approach discover new/existing viruses vectored by...
Abstract Objective To report isolation of Leishmania major strains obtained from 18 Turkish autochthonous cutaneous leishmaniasis ( CL ) patients infected with L. between 2011 and 2014. Methods Initial diagnosis relied on microscopy culture in enriched medium, prepared by adding specific amounts liver extract, protein lipid sources to NNN medium. Promastigotes were then transferred RPMI medium including 10% foetal calf serum for mass culture. Species‐specific real‐time PCR targeting ITS 1...
Progress with the treatment of cutaneous leishmaniasis (CL) has been hampered by inconsistent methodologies used to assess effects. A sizable number trials conducted over years generated only weak evidence backing current recommendations, as shown systematic reviews on old-world and new-world CL (OWCL NWCL).Using a previously published guidance paper trial methodology reference, consensus was sought key parameters including core eligibility outcome measures, among OWCL (7 countries, 10...