A5029940242- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Pharmacological Effects and Assays
- Analytical chemistry methods development
- Antibiotics Pharmacokinetics and Efficacy
- Electrochemical Analysis and Applications
- Antibiotic Resistance in Bacteria
- Dye analysis and toxicity
- Pharmacology and Obesity Treatment
- Muscle metabolism and nutrition
- Microfluidic and Capillary Electrophoresis Applications
- Computational Drug Discovery Methods
- Medical Imaging Techniques and Applications
- Bacterial Identification and Susceptibility Testing
- Pharmacogenetics and Drug Metabolism
- Estrogen and related hormone effects
- Metabolomics and Mass Spectrometry Studies
- Hormonal and reproductive studies
- Lanthanide and Transition Metal Complexes
- Nanoparticles: synthesis and applications
- Pharmaceutical studies and practices
- Nanomaterials for catalytic reactions
- Advanced NMR Techniques and Applications
South Valley University
2016-2025
Zagazig University
2023
Assiut University
2010-2014
The global shift towards adopting White and Green analytical chemistry (WAC, GAC) principles reflects a growing commitment to sustainability across various scientific disciplines. This trend is parallel the recent release of ICH Q14 Q2(R2) guidelines, which promote implementation Analytical Quality by Design (AQbD) concepts into method development validation. Consequently, QbD has recently widened its domain over vast areas chemistry. In this context, present study introduces novel...
An innovative quality by design-integrated VA-SALLME-core–shell chromatographic method was developed for the simultaneous determination of DOR and TIM in plasma.
A highly sensitive and selective HPLC method with UV detection was developed for the determination of cefepime in goat plasma milk. The proposed based on complexation Hg(I) ions that imparts high selectivity enhancement sensitivity which enabled analysis complex matrices such as Detection performed at 263 nm, using cefuroxime sodium an internal standard. Chromatographic separation standard achieved Aqua RP-C(18) column methanol/triethylamine-acetate buffer, pH 3.5 (18:82, v/v) mobile phase a...
A spectrophotometric procedure was developed for determination of cefepime depending on the complexation drug with Hg2(NO3)2 in acid medium (pH 3.5) and measuring absorbance at 263 nm. Different variables affecting reaction were studied optimized. Under optimized conditions, linear relationship good correlation coefficient (0.999) found between concentration range 3.65-40 µg ml-1. The limits detection quantitation 1.20 3.65 ml-1 respectively. stoichiometry using Yoe Jones method to be 1:2...
Hypertension can begin in childhood; elevated blood pressure children is known as pediatric hypertension. Contrary to adult hypertension, there a scarcity of commercial medications suitable for the treatment The aim this study was develop orally dispersible films (ODFs) loaded with captopril hypertension children. Captopril-loaded ODFs were composed different blends synthetic polymers, such polyvinyl alcohol (PVA) and pyrrolidone, natural sodium alginate (SA) gelatin. characterized based on...
Background The complex metabolic profile of tamoxifen anticancer drug and polymorphism in its metabolizing enzymes particularly CYP2D6 contribute to the high-observed inter-individual variability main active metabolite endoxifen. Therapeutic monitoring endoxifen may play a key role optimizing therapy, control both adverse effects cancer recurrence. This pilot study aims assess clinical benefits applying measurement during therapy patients with breast cancer. Methods Adult premenopausal ≥ 18...