A5109440470- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Rheumatoid Arthritis Research and Therapies
- Advanced Combustion Engine Technologies
- Research in Cotton Cultivation
- Pharmacological Effects of Natural Compounds
- Combustion and flame dynamics
- Alkaline Phosphatase Research Studies
- Natural product bioactivities and synthesis
- Psoriasis: Treatment and Pathogenesis
- Advancements in Transdermal Drug Delivery
- Pediatric health and respiratory diseases
- NF-κB Signaling Pathways
- Phytochemistry and Biological Activities
- Nosocomial Infections in ICU
- Estrogen and related hormone effects
- Pneumocystis jirovecii pneumonia detection and treatment
- Plant Stress Responses and Tolerance
- Vehicle emissions and performance
- Inflammatory mediators and NSAID effects
- Plant Virus Research Studies
- Systemic Lupus Erythematosus Research
- Pleural and Pulmonary Diseases
- Catalytic Processes in Materials Science
- Metabolomics and Mass Spectrometry Studies
Wenzhou City People's Hospital
2025
Hunan Rice Research Institute
2020
Anhui University of Traditional Chinese Medicine
2016-2018
Peking University
2018
Beijing Jishuitan Hospital
2018
Ministry of Education of the People's Republic of China
2017
Anhui Agricultural University
2017
Jiangsu University
2013-2014
This study aims to evaluate the utility of targeted next-generation sequencing (tNGS) in bronchoalveolar lavage fluid (BALF) for hospitalized patients with pulmonary infections. A cohort 358 who received diagnosis and treatment respiratory infections department Respiratory Medicine at Wenzhou People's hospital from January 2023 April 2024 were selected this study. The BALF was analyzed using tNGS, diagnostic efficacy tNGS subsequently compared that conventional testing methods (CTs) pathogen...
The aim of the study was to isolate gossypol-degrading bacteria and assess its potential for gossypol degradation. Rumen liquid collected from fistulated cows grazing experimental pasture. Approximately 1 mL rumen spread onto basal medium plates containing 2 g/L as only source carbon then cultured at 39°C bacteria. isolated colonies were 6 h their size shape observed by microscope scanning electron microscope. 16S rRNA gene sequenced aligned using National Center Biotechnology...
Geniposide (GE), an iridoid glycoside compound purified from Gardenia jasminoides Ellis, has antiinflammatory and other pharmacological effects, but its mechanism of actions on rheumatoid arthritis (RA) have not been clarified. The purpose this article was to investigate the effects GE collagen-induced (CIA) rats feasible mechanisms. Collagen-induced induced by injection chicken type II collagen emulsion. were orally administered with (33, 66, 132 mg/kg) days 14 30 after immunization....
A simple and effective method of high performance liquid chromatography (HPLC) with diode array detection was established to identify the origin Achyranthes bidentata Blume evaluate its quality, based on chromatographic fingerprint combined similarity analysis, hierarchical cluster analysis quantitative multi-components by single marker (QAMS). In fingerprint, 16 peaks were selected as common model similarities among 18 batches (S1–S18) A. samples collected from different origins in China....
Rheumatoid arthritis (RA) is a systemic, Th1 cytokine-predominant autoimmune disease result in chronic and inflammatory disorder. Geniposide (GE), an iridoid glycoside compound that purified from Gardenia jasminoides Ellis, has antiinflammatory other immunoregulatory effects, but its exact mechanism of actions on RA unknown. The aim this study was to elucidate antiinflammation effects GE adjuvant (AA) rats possible immune tolerance mechanisms. Male Sprague–Dawley were administered with (30,...
Microdialysis, a sampling method for pharmacokinetics⁻pharmacodynamics (PK⁻PD) modeling in preclinical and clinical studies, is convenient vivo technique. Geniposide (GE), an iridoid glycoside compound, the major active ingredient of Gardenia jasminoides Ellis fruit which has anti-inflammatory effect. In this study, articular cavity microdialysis system adjuvant arthritic (AA) rats was established to study effect GE on release prostaglandin E₂ (PGE₂) AA induced by Freund's complete (FCA). An...
Objective: To compare the characteristics of Mycoplasma pneumoniae necrotizing pneumonia (MPNP) and bacterial (BNP), explore biomarkers for differentiation MPNP from BNP. Methods: A retrospective, observational study 52 (NP) cases who were hospitalized in our hospital January 2008 to December 2017 was conducted. According pathogen causing NP, patients divided into two groups, BNP MPNP, clinical manifestations, laboratory data, imaging findings, course prognosis between these groups analyzed....
Development of a reliable and selective anti-inflammatory agent cyclooxygenase-2 (COX-2), induced or up-regulated by inflammatory/injury stimulus such as IL-1β, TNF-α LPS in the various types organs, tissues cells, with low side effects is long-standing medicinal chemistry problem significant social implications.To target druggable enzymome COX-2 exploiting NSAIDs genipin (GEP) infection.The compound aspirin GEP ester (AGE) was designed computer-assisted screening, synthesized esterification...
As a study of natural gas engine, three-dimensional numerical simulations diesel injection rates were conducted by using AVL FIRE code. And particularly the effects in pilot jets on engine combustion and emission analyzed. It is found that rate plays an important role emission, slow ending keeps lower NO Soot.
Numerical simulation of the combustion and emissions HPDI engine under different natural gas substitution rate was performed using AVL FIRE . The effects on cylinder average pressure, temperature, heat release rate, NO Soot were analyzed four typical conditions. Cylinder pressure temperature decrease with increasing rate. Furthermore, emission will significantly same circumstances.
Objective To investigate the distribution of pathogenic bacteria and drug resistance isolated from inpatients with lower respiratory tract infection in Beijing Jishuitan Hospital. Methods A total 2 016 sputum or bronchial secretions patients were engaged 2013 to 2016, results analyzed retrospectively. Results A strains isolated, 1 873 gram-negative (92.9%) , which mainly for Acinetobacter baumanii (361 strains, 17.9%) Pseudomonas aeruginosa (328 16.3%) Klebsiella pneumonia (269...