A5022852363- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Heart Disease Studies
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Pain Management
- Mechanical Circulatory Support Devices
- Cardiovascular Syncope and Autonomic Disorders
- Airway Management and Intubation Techniques
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Pediatric Pain Management Techniques
- Cardiac Structural Anomalies and Repair
- Atomic and Subatomic Physics Research
- Congenital Diaphragmatic Hernia Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Tracheal and airway disorders
- Nausea and vomiting management
- Organ Transplantation Techniques and Outcomes
- Pain Mechanisms and Treatments
Freeman Hospital
2010-2022
University of Toronto
2007
Hospital for Sick Children
2007
SickKids Foundation
2007
Summary Background: A previously published pharmacokinetic simulation suggested a simple manual infusion regimen to achieve propofol plasma concentrations of 3 μg·ml −1 . This study investigated if variation in rates is able distinct and whether these are close the predicted by Kataria model. Methods: With Research Ethics Board approval written parental consent, total 17 healthy children requiring general anaesthesia were enrolled. Following inhalational induction anaesthesia, bolus 5 mg·kg...
The incidence of awareness in the pediatric population is reported as high 1 : 125. An online survey was conducted about current perception and practice members British French anesthesia societies regarding during general anesthesia.Following approval executive committees societies, with a valid email contact address were invited to participate web-based survey. Perceived risk factors, use monitors, pre- postoperative discussions well personal experience enquired.A total 302 (51%) responded...
Summary Background It is important that postoperative analgesic management after thoracotomy very effective in order to optimize recovery. A regional technique such as an epidural or a paravertebral catheter with infusion of local anesthetic may be supplemented systemically administered drugs achieve satisfactory analgesia. Objective The objective this observational study was evaluate whether delivered via surgically placed together systemic analgesics associated low pain scores and...
Objectives To describe a novel strategy for the management of infants with hypoplastic left heart syndrome (HLHS) and intact atrial septum. Antenatally diagnosed are delivered in cardiac theatre immediate decompression (LAD) using hybrid transatrial stent insertion (HTSI) via sternotomy is carried out. Background HLHS septum condition incompatible life following placental separation. Despite number reported strategies survival these remains much worse than those born an adequate...
Perioperative trans-esophageal echocardiography ('TEE') is widely used for the assessment of anatomy/repair congenital cardiac defects. It recognised that there are risks associated with its use.We wished, by means a contemporaneous prospective national audit over six-month period, to establish what proportion TEE studies in children complicated major upper gastrointestinal or aerodigestive tract trauma.After obtaining appropriate local institutional ethics committee approval, rate and...
Ventricular assist devices (VADs) are increasingly being implanted in children, yet there is little literature to guide anesthetic management for these procedures.To describe the pediatric population presenting VAD implantation and patients receive. To compare (a) children under over 12 months of age (b) with without congenital heart disease.Retrospective review aged 0 17 years who underwent at a single center between 2014 2019.Seventy-seven VADs were 68 (46 left VADs, 24 biventricular 6...
The glutamate-nitric oxide-cyclic guanosine 3',5'-monophosphate (cGMP) pathway is potentially an effective target for general anesthetics. Plasma cGMP concentrations are reduced after increase in predicted plasma propofol during sedation healthy adult volunteers. We hypothesized that measured concentration leads to a reduction anesthetized children.Eighteen children aged 46.8 (+/-19.6) mo, requiring anesthesia lower body surgical procedures were enrolled. After inhaled induction, tracheal...
Engelhardt, T.; McCheyne, A J.; Karsli, C.; Luginbuehl, I.; Bissonnette, B. Author Information
Poor ventricular assist device filling is often seen in patients supported with the Berlin Heart Excor. Caval stenosis an uncommon complication following bicaval approach to orthotopic heart transplantation. We report case of a five-year-old female patient post transplantation whose poor right immediately resolved management caval stenosis.