A5017834211- Diphtheria, Corynebacterium, and Tetanus
- Mycobacterium research and diagnosis
- Veterinary medicine and infectious diseases
- Microbial infections and disease research
- Clostridium difficile and Clostridium perfringens research
- Animal health and immunology
- Fish biology, ecology, and behavior
- Vector-borne infectious diseases
- Vector-Borne Animal Diseases
- Turtle Biology and Conservation
- Toxoplasma gondii Research Studies
- Aquaculture Nutrition and Growth
- Viral Infections and Vectors
- Ichthyology and Marine Biology
- vaccines and immunoinformatics approaches
- Mosquito-borne diseases and control
- Enterobacteriaceae and Cronobacter Research
- Aquaculture disease management and microbiota
- Research on Leishmaniasis Studies
- Reproductive Physiology in Livestock
- Bird parasitology and diseases
- Herpesvirus Infections and Treatments
- Leptospirosis research and findings
- Marine animal studies overview
- Syphilis Diagnosis and Treatment
Universidade Federal da Bahia
2012-2024
Hospital Ana Nery
2013-2022
Universidade Estadual de Santa Cruz
2022
Autoliv (Sweden)
2018
Faculdade de Tecnologia e Ciências
2014
Fundação de Amparo à Pesquisa do Estado da Bahia
2012
Fundação de Estudos e Pesquisas Aquáticas
2006
Corynebacterium pseudotuberculosis is a member of the Corynebacterium, Mycobacterium and Nocardia (CMN) group that comprises species medical, veterinary biotechnological interest. This pathogen mainly affects small ruminants, causing caseous lymphadenitis (CLA), but it also infects bovines, equines, pigs, deer, camels humans, showing its zoonotic relevance. Phospholipase D (PLD) toxic lipid cell wall are two most wellstudied virulence factors this bacterium. They responsible, in part, for...
Corynebacterium pseudotuberculosis is the etiologic agent of caseous lymphadenitis, which a serious, economically important problem for sheep production. We examined seroprevalence infection by C. and possible risk factors associated with lymphadenitis in herds state Minas Gerais, Brazil. Samples were collected from 642 97 farms. Sera all tested ELISA antibodies against pseudotuberculosis. A questionnaire was applied to gather data on farm, herd, farmer, individual animal (breed, sex age)....
The genus Leptospira is composed of pathogenic and saprophytic spirochetes. Pathogenic the etiological agent leptospirosis, a globally spread neglected disease. A key ecological feature some species their ability to survive both within outside host. For most leptospires, persist host associated with biofilm formation, important bacterial strategy face overcome hostile environmental conditions. architecture biochemistry leptospiral biofilms are rather well understood; however, genetic program...
In the current study, applicability of quantification gamma interferon (IFN-γ) levels for detection animals infected with Corynebacterium pseudotuberculosis and determining caseous lymphadenitis (CLA) clinical status was evaluated. Peripheral blood leukocytes were collected from CLA nonendemic areas animals, seropositive without signs disease, presenting signs. The stimulated C. pseudotuberculosis—secreted antigens that concentrated by three-phase partitioning technique. An ovine IFN-γ...
Sheep caseous lymphadenitis (CLA), caused by Corynebacterium pseudotuberculosis (Cp), is associated with direct economic losses and presents significant zoonotic potential. Despite the importance of disease, a satisfactory vaccine model has not been developed. Thus, this study aimed to investigate association between haptoglobin (Hp) IgM levels clinical progression CLA in primarily infected sheep immunized Cp- secreted antigens adjuvanted Quillaja saponaria saponins. These animals were kept...
Corynebacterium pseudotuberculosis is the etiologic agent of caseous lymphadenitis (CLA), a chronic disease that affects goats and sheep, characterized by granuloma formation in subcutaneous internal lymph nodes. CLA causes significant economic losses to commercial goat herds. In this study, we aimed test secreted antigens from T1 strain bacteria grown brain heart infusion (BHI) broth an indirect ELISA system determine presence specific immunoglobulins against C. pseudotuberculosis. We...
Background C orynebacterium pseudotuberculosis is the etiologic agent of caseous lymphadenitis ( CLA ), a disease that affects small ruminants and responsible for economic losses, including condemnation carcasses damaged hides. Objective The goal this study was to determine if serum haptoglobin plasma fibrinogen concentrations peripheral blood leukocyte counts are biologic markers in sheep. Methods Blood from 38 clinically healthy S anta‐ I nês ewes selected segregated commercial flock 2500...
Previous works defining antigens that might be used as vaccine targets against Corynebacterium pseudotuberculosis, which is the causative agent of sheep and goat caseous lymphadenitis, have focused on secreted proteins produced in a chemically defined culture media. Considering such not reflect repertoire expressed during infection conditions, this experiment aimed to investigate membrane-associated with pathogenic potential by C. pseudotuberculosis grown directly animal serum. Its been...
Caseous lymphadenitis (LC) is a chronic contagious disease caused by Corynebacterium pseudotuberculosis, which mainly affects goats and sheep. Vaccination an effective but not yet well-established method, partly due to lack of knowledge surrounding the most immunoprotective components. The present study aimed quantify compare in vivo expression genes pld (phospholipase D), cpp (CP40), nanH (neuraminidase H), sodC (superoxide dismutase C) spaC (adhesin) using qRT-PCR, with respective vitro....
Objectives: Ureaplasma diversum is a pathogen of cows that may cause intense inflammatory responses in the reproductive tract and interfere with bovine reproduction. The aims this study were to evaluate immune response blastocysts macrophages U. infection invasion capacity microorganism blastocysts. Methods: Viable heat-inactivated strains ATCC 49782 CI-GOTA their extracted membrane lipoproteins inoculated presence or absence signaling blockers Toll-like Receptor (TLR) 4, TLR2/4 Nuclear...
Abstract Background Ureaplasma diversum has numerous virulence factors that contribute to pathogenesis in cattle, including Lipid-associated membrane proteins (LAMPs). Therefore, the objectives of this study were evaluate silico important characteristics for immunobiological applications and heterologous expression 36 LAMPs U. (UdLAMPs) and, also, verify by conventional PCR distribution these antigens strains Brazilian states (Bahia, Minas Gerais, São Paulo, Mato Grosso do Sul). The Manatee...
Resumo: A ovinocultura no Brasil é uma atividade em grande expansão e, com o aumento da demanda mundial por carne ovina, aumentou-se interesse monitoramento sanidade do rebanho, utilizando diversas ferramentas como auxiliares diagnóstico clínico, tais os intervalos de referência séricos. Os elementos minerais constituem 2 a 5,5% corpo dos vertebrados, exercendo funções organismo. O objetivo deste trabalho foi obter para eletrólitos magnésio, fósforo, cloreto e cálcio ovinos das raças Dorper...
This research aimed to establish reference values for hemogram and clinical biochemistry, aiming at evaluating the liver function of healthy macaws (Ara sp.), with influence species on blood constituents, in order contribute health monitoring this kept ecological farms state Bahia (Brazil). We used forty-five samples from three distinct species: green-winged macaw chloroptera), blue-and-yellow ararauna) scarlet macao). A total 3.5 mL was collected ulnar vein each bird: 1.5 placed tubes...
Na América do Sul, alguns canídeos silvestres são considerados reservatórios naturais da Leishmania chagasi. A resposta imunológica desses animais à é pouco conhecida, havendo a necessidade de métodos diagnósticos adequados para esse fim. No presente estudo, descrita padronização ensaio imunoenzimático indireto (ELISA) o diagnóstico sorológico leishmaniose visceral em brasileiros. Foram estudadas amostras soro e plasma 12 cativos: sete lobos-guará (Chrysocyon brachyurus), três raposinhas...
The understanding of bioprocesses has been allowed the increase techniques to study cellular interactions, such as flow cytometry (FC). This technic is an important tool for counting and classifying microscopic particles suspended in flowing liquid medium, analyzing parameters from cells diverse origins, including bacteria. Thus, aim this was standardize protocols by evaluate absolute count physiological aspects Corynebacterium pseudotuberculosis murine phagocytic cells. C. grown 0.5% BHI...
Abstract Background Ureaplasma diversum is a pathogen found in the genital tract of cattle and associated with disorders such as infertility, placentitis, abortion, birth weak calves, low sperm motility, seminal vesiculitis epididymitis. There are few studies evaluating genetic diversity U. strains their influence on immune response cattle. Therefore, to better understand relationships pathogenicity , multilocus sequence typing (MLST) scheme was performed characterize ATCC 49782 strain...
The Rhipicephalus (Boophilus) microplus tick is responsible for large losses in the national livestock, mainly due to reduction productive performance of cattle, such damages estimated billions dollars per year are proved by direct action hematophagia parasite that addition transmitter other pathogens. development resistance main classes acaricides currently employed has been widely reported, as well occurrence residues animal products and ecological problems. present work had objective...
In Brazil, the agreements between Public Administration and third parties, in which there is application of public resources availability benefi ts, must be governed by legal terms, since process needs to as much a good suitability possible. view these notes considering that Brazil had already been reforming norms related procurement, it possible problematize about signifi cant changes old current law, establish relationship ts impacts management small cities. Considering questions, aim this...
A dieta exerce efeito pronunciado na composição das carcaças de peixes. Neste trabalho, foi avaliada a qualidade nutricional da fração lipídica do tecido muscular tilápias Nilo (Oreochromis niloticus) submetidas dietas com diferentes teores óleo soja (OS). Os peixes foram alimentados por 21 dias ração contendo 5,98% lipídios totais (LT) oriundos comercial, sem adição (A), 2% (B) e 4% (C). Não houve diferenças significativas (p > 0,05) entre os umidade, cinzas, proteína bruta LT (0,98%...