- Atrial Fibrillation Management and Outcomes
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Clinical practice guidelines implementation
- Pharmacovigilance and Adverse Drug Reactions
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Anesthesia and Sedative Agents
- Pharmaceutical industry and healthcare
- Cardiac electrophysiology and arrhythmias
- Hemodynamic Monitoring and Therapy
- Heparin-Induced Thrombocytopenia and Thrombosis
Vrije Universiteit Brussel
2018-2023
Universitair Ziekenhuis Brussel
2018-2023
Geneeskundige en Gezondheidsdienst
2018
Pharmac
2017
Background and Objectives: Appropriate dosing of direct oral anticoagulants (DOACs) is required to avoid under- overdosing that may precipitate strokes or thromboembolic events bleedings, respectively. Our objective was analyze the appropriateness DOAC according summaries product characteristics (SmPC). Furthermore, determinants for inappropriate prescribing were investigated. Methodology: Retrospective cohort study hospitalized patients aged ≥60 years with at least one intake during...
Objective This study aimed to assess implementation adherence (how well the patient’s actual intake matches prescribed dosing regimen) non-vitamin K antagonist oral anticoagulants (NOACs) and explore experiences with beliefs about NOACs in a real-world sample of long-term NOAC users. Methods A cross-sectional observational was conducted home-dwelling adults who started taking at least 1 year prior inclusion. Pharmacy dispensing data were used calculate Medication Possession Ratio (MPR)....
To analyse the appropriateness of direct oral anticoagulant (DOAC) dosing and determinants for under-and overdosing as well acceptance implementation rates pharmacists' interventions.Cross-sectional study in a tertiary hospital hospitalized patients with atrial fibrillation on DOACs 2019 (n = 1688). Primary outcome was proportion inappropriate DOAC prescribing identification overdosing. Secondary outcomes included recommendations determination reasons...
Direct oral anticoagulants (DOACs) are increasingly used for stroke prevention in atrial fibrillation. However, little is known about the association between medication adherence, patient satisfaction and treatment knowledge. The objective was to determine patients' DOAC adherence their over time. Furthermore, we respectively investigated possible associations of knowledge relation adherence.Longitudinal study conducted fibrillation patients hospitalized 2019 a tertiary university hospital....
Aim: To analyze the appropriateness of DOAC dosing and determinants for under-and overdosing as well acceptance implementation rates interventions by clinical pharmacists. Methods: Cross-sectional study from January 2019-December 2019 in a tertiary hospital hospitalized patients with atrial fibrillation on DOACs (n=1688). Primary outcome was proportion inappropriate prescribing identification overdosing. Secondary outcomes included pharmacists’ advices determination reasons...
<h3>Background</h3> The introduction of the direct oral anticoagulants (DOACs) widened options for anticoagulation in atrial fibrillation (AF) and venous thromboembolism. Although they have made more convenient, caution is warranted patients with renal impairment to decrease bleeding risk as are partly renally cleared. <h3>Purpose</h3> purpose this study was determine prescribing accuracy dabigatran etexilate, rivaroxaban apixaban according summaries product characteristics. Second,...
Abstract Background The emergence of non-vitamin K antagonist oral anticoagulants (NOAC) has caused a paradigm shift in anticoagulation therapy, with NOAC being increasingly used compared to vitamin antagonists. Despite the numerous RCTs NOAC, further follow-up on how this high risk new drug class is real-world clinical practice warranted. Purpose This study aimed describe use primary care sample long-term users, and investigated (i) adherence, (ii) patients' perceptions, (iii) interactions...