A5000211984- Pharmaceutical Practices and Patient Outcomes
- Atrial Fibrillation Management and Outcomes
- Electronic Health Records Systems
- Pharmacovigilance and Adverse Drug Reactions
- Biomedical Text Mining and Ontologies
- Pharmaceutical studies and practices
- Healthcare Technology and Patient Monitoring
- Patient Safety and Medication Errors
- Health Systems, Economic Evaluations, Quality of Life
- Venous Thromboembolism Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Acute Ischemic Stroke Management
- Medication Adherence and Compliance
- Blood Pressure and Hypertension Studies
- Health Literacy and Information Accessibility
- Stroke Rehabilitation and Recovery
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Medical Research and Practices
- ECG Monitoring and Analysis
- Computational Drug Discovery Methods
- Hemodynamic Monitoring and Therapy
- Cardiac Arrhythmias and Treatments
- Dutch Social and Cultural Studies
- Genetic Neurodegenerative Diseases
Vrije Universiteit Brussel
2014-2025
Universitair Ziekenhuis Brussel
2010-2025
Pharmac
2014-2018
Institut du Cerveau
2018
American Pharmacists Association
2018
Hôpital de la Providence
1991
CV Cardiovascular CYP Cytochrome P (CYP) Unfractionated heparin ULN Upper limit of normal VENTURE-AF Active-controlled multi-center study with blind-adjudication designed to evaluate the safety uninterrupted Rivaroxaban and vitamin K antagonists in subjects undergoing catheter ablation for non-valvular Atrial Fibrillation VHD Valvular heart disease VKA Vitamin antagonist VTE Venous thromboembolic event WOEST What is Optimal antiplatelet anticoagulant therapy patients oral anticoagulation...
Medication discrepancies have the potential to cause harm. reconciliation by clinical pharmacists aims prevent and other drug-related problems.To determine how often in physician-acquired medication history result during hospitalization at discharge. Secondary objectives were influence of pharmacists' interventions on investigate possible patient-related determinants for experiencing discrepancies.This was a retrospective, single-center, cohort study patients who admitted acute geriatric...
Background: Accurate medication histories at hospital admission are an important element of safety. Discrepancies may have clinically significant consequences, especially in the elderly population. Objective: To assess clinical pharmacist's performance obtaining patients' and reconciling these data with medical records orders whether residential situation prior to hospitalization influences number drug discrepancies. Methods: A prospective observational study was conducted a 29-bed acute...
Background and Objectives: Appropriate dosing of direct oral anticoagulants (DOACs) is required to avoid under- overdosing that may precipitate strokes or thromboembolic events bleedings, respectively. Our objective was analyze the appropriateness DOAC according summaries product characteristics (SmPC). Furthermore, determinants for inappropriate prescribing were investigated. Methodology: Retrospective cohort study hospitalized patients aged ≥60 years with at least one intake during...
Medication discrepancies in discharge medication lists can lead to errors and adverse drug events following discharge.To determine the incidence type of between letter for primary care physician patient list as well identify possible patient-related determinants experiencing discrepancies.A retrospective, single-center, cohort study patients discharged from acute geriatric department a Belgian university hospital September 2009 April 2010 was performed. Medications listed were compared with...
Evaluation of the effect six optimization strategies in a clinical decision support system (CDSS) for drug-drug interaction (DDI) screening on alert burden and acceptance description pharmacist intervention acceptance.Optimizations new CDSS were customization knowledge base (with addition 67 extra DDIs changes severity classification), design, required override reasons most serious alerts, creation DDI-specific intervals, patient-specific alerting, real-time follow-up all alerts by...
To analyse the appropriateness of direct oral anticoagulant (DOAC) dosing and determinants for under-and overdosing as well acceptance implementation rates pharmacists' interventions.Cross-sectional study in a tertiary hospital hospitalized patients with atrial fibrillation on DOACs 2019 (n = 1688). Primary outcome was proportion inappropriate DOAC prescribing identification overdosing. Secondary outcomes included recommendations determination reasons...
Developing and implementing clinical decision support systems (CDSSs) is time-consuming costly. Therefore, prioritization of the most relevant warranted. The physician's perceived usefulness has been identified as a decisive reason for using CDSSs. objective this study was to investigate different types CDSSs identify user needs expectations regarding future CDSSs.Cross-sectional single-centre survey among physicians with assignment in university hospital. Physicians were questioned about...
<h3>Background and Importance</h3> Poor documentation of drug hypersensitivities in patient records can lead to allergic reactions. Developing tools for accurate hypersensitivity prevent prescription errors. However, there is no consensus on how should be routinely documented electronically. We developed a new structured coded tool with semi-automatic de-labelling feature collaboration end-users<sup>1</sup> implemented it our university hospital May 2022. <h3>Aim Objectives</h3> To evaluate...
Stroke is a very time-sensitive pathology, and many new solutions target the optimization of prehospital stroke care to improve management process. In-ambulance telemedicine, defined by live bidirectional audio-video between patient neurologist in moving ambulance automated transfer vital parameters, promising approach speed up quality acute care. Currently, no evidence exists on cost effectiveness in-ambulance telemedicine.We aim develop first model for telemedicine use this estimate time...
To describe a reversible neurological condition resembling crossed midbrain syndrome resulting from high frequency stimulation (HFS) in the midbrain.Postoperative evaluation of quadripolar electrodes implanted area subthalamic nucleus 25 patients with Parkinson's disease (PD) successfully treated by HFS.Four experienced acute diplopia, dystonic posture and tremor contralateral upper limb when white matter between red substantia nigra was stimulated. The motor signs resembled those caused...
Intravenous (IV) fluids are frequently involved in iatrogenic complications hospitalized patients. Knowledge of IV seems inadequate and is not covered sufficiently standard medical education.Two surveys were developed, based on the 2016 British National Institute for Health Care Excellence guideline 'IV fluid therapy adults hospital', to provide insight learning needs expectations physicians nurses. Each survey focused profession-specific practice consisted three parts: demographics,...
Many clinical decision support systems trigger warning alerts for drug-drug interactions potentially leading to QT prolongation and torsades de pointes (QT-DDIs). Unfortunately, there is overalerting underalerting because stratification only based on a fixed QT-DDI severity level. We aimed improve alerting by developing validating risk prediction model considering patient- drug-related factors.We fitted 31 predictor candidates stepwise linear regression 1000 bootstrap samples selected the...