A5070589057- Pharmaceutical Practices and Patient Outcomes
- Palliative Care and End-of-Life Issues
- Drug-Induced Hepatotoxicity and Protection
- Liver Disease and Transplantation
- Pharmaceutical studies and practices
- Medication Adherence and Compliance
- Patient Dignity and Privacy
- Pharmacy and Medical Practices
- Liver Disease Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Health Systems, Economic Evaluations, Quality of Life
- Patient Safety and Medication Errors
- Pharmacovigilance and Adverse Drug Reactions
- Academic integrity and plagiarism
- Schizophrenia research and treatment
- Pharmacological Effects and Toxicity Studies
- Health Literacy and Information Accessibility
- Pain Management and Opioid Use
- Blood Pressure and Hypertension Studies
- Patient-Provider Communication in Healthcare
- SARS-CoV-2 and COVID-19 Research
- Clinical practice guidelines implementation
- Pharmacogenetics and Drug Metabolism
- Computational Drug Discovery Methods
- Food Allergy and Anaphylaxis Research
Health Foundation
2020-2023
Amsterdam UMC Location University of Amsterdam
2023
Sichuan University
2023
West China Hospital of Sichuan University
2023
Royal Dutch Pharmacists Association
2023
University of Waterloo
2023
Erasmus MC
2018-2021
SIR Institute for Pharmacy Practice and Policy
2016-2020
University of Groningen
2018-2019
Amsterdam UMC Location Vrije Universiteit Amsterdam
2006-2011
Background Hospital admissions are a risk factor for the occurrence of unintended medication discrepancies between drugs used before admission and after discharge. To diminish such improve quality care, reconciliation has been developed. The exact contribution patient counseling to process is unknown, especially not when compared with community pharmacy records, which considered reliable in Netherlands. Objective examine effect without among patients at time hospital discharge on number type...
To the Editor, The availability of new vaccines against SARS-CoV-2 brings promising opportunities to prevent people from getting infected and developing COVID-19. As with other drugs, can cause adverse drug reactions (ADRs). Although generally ADRs are mild serious very rare,1 anaphylactic were reported after administration COVID-19 vaccines.2 Cabanillas et al provide valuable background information that these might be caused by polyethylene glycols (PEGs) part lipid nanoparticles (LNPs)...
Since the widespread availability of Chat Generative Pre-Trained Transformer (ChatGPT), public is confronted with accessible artificial intelligence tools. There limited knowledge on use, concerns and opportunities ChatGPT in pharmacy practice Netherlands. The aims this study were to explore extent type use community identify for practice. A questionnaire was developed, tested distributed professionals that work pharmacy. answers analysed descriptively using frequency tables. Of all...
Aims Proton pump inhibitors (PPIs) belong to the most frequently used drugs, also in patients with cirrhosis. PPIs are extensively metabolized by liver, but practice guidance on prescribing cirrhosis is lacking. We aim develop practical safe use of Methods A systematic literature search identified studies safety (i.e. adverse events) and pharmacokinetics cirrhotic patients. This evidence data from product information was reviewed an expert panel who classified drugs as safe; no additional...
There is a lack of clear definition and inclusion criteria in palliative care research. The aim this study was to describe consequences three the build up different populations, studied terms size, number doctor-patient contacts demographic characteristics. General practitioners received questionnaire for all patients who died during second Dutch National Survey Practice (n=2194), determine whether (1) non-curative treatment; (2) care; (3) death expected (total response rate =73%). criterion...
Adherence to medication in patients with type 2 diabetes varies widely, yet the factors that influence adherence according are not fully known. The aim of this study is explore both related high and lower levels experienced their use.Primary care Netherlands.Qualitative, semi-structured interviews were performed 20 diabetes. Interviews audio-taped transcribed verbatim. Transcripts coded analysed using content analysis constant comparison. Main outcome measure experiences opinions concerning...
To investigate the needs of Dutch general practitioners on discharge medication, both regarding content, timing and appreciation pharmacotherapeutic advice from clinical pharmacists.A teaching hospital in Amsterdam, The Netherlands.A prospective observational study was performed. A questionnaire with regard to optimal (including way information transfer) posted 464 practitioners. One reminder sent.Description assessed. For each question categories comments frequency tables were made....
Objective. To investigate the occurrence and predictors of interdisciplinary cooperation GPs with other caregivers in palliative care at home. Design. In a prospective study among 96 general practices, involved identified all dying patients during period 12 months. The received an additional post-mortem questionnaire for each patient who died period, registered healthcare providers whom they cooperated. Multivariable logistic regression analysis was used to identify GP caregivers. Setting....
Most people with an incurable disease prefer to stay and die at home, cared for by their general practitioner (GP). This paper aims describing the prevalence of symptoms in patients receiving palliative care home. Within framework a nation wide survey practice Netherlands, GPs received questionnaire all who died within 1-year period determine whether (n = 2,194). The response rate was 73% 1,608), 38% these until death. Information regarding encounters during last 3 months life derived from...
Abstract Background Medication errors occur frequently at points of transition in care. The key problems causing these medication are: incomplete and inappropriate reconciliation hospital discharge (partly arising from inadequate admission), insufficient patient information (especially within a multicultural population) communication to the next health care provider. Whether interventions aimed combination aspects indeed result less discontinuity associated harm is uncertain. Therefore main...
Patients with cirrhosis are at risk for adverse drug reactions (ADRs) due to altered pharmacokinetics and pharmacodynamics. We aimed determine the prevalence of prescriptions potential safety these in a real-world cohort patients cirrhosis. This was retrospective study based on linked data from Out-patient Pharmacy Database Hospitalisation PHARMO Network. diagnosis between January 1998 December 2015 were included. Follow-up ended when patient underwent liver transplant, died, transferred out...
Drug-disease interactions negatively affect the benefit/risk ratio of drugs for specific populations. In these conditions should be avoided, adjusted, or accompanied by extra monitoring. The motivation many drug-disease in Summary Product Characteristics (SmPC) is sometimes insufficiently supported (accessible) evidence. As a consequence translation SmPC to clinical practice may lead non-specific recommendations. For this information real world, it necessary evaluate available knowledge...
Abstract Purpose To examine what pain and adjuvant medication is prescribed in palliative care patients at home The Netherlands. Methods In a nationwide, representative, prospective study general practice Netherlands, was registered 95 practices with listed population of 374 070 patients. GPs identified those who received retrospective survey the 2169 died within 1‐year period. We analysed analgesics, laxatives anti‐emetics that were during last 3 months life for these Results response rate...
Pain is still one of the most frequently occurring symptoms at end life, although it can be treated satisfactorily in cases if physician has adequate knowledge. In Netherlands, almost 60% patients with non-acute illnesses die home where life care coordinated by general practitioner (GP); about 30% hospitals (cared for clinical specialists), and 10% nursing homes elderly physicians).The research question this study is: what level knowledge Dutch physicians concerning pain management use...
Background To improve continuity of care at hospital admission and discharge to decrease medication errors pharmaceutical programs are developed. This study aims determine the cost-effectiveness COACH program in comparison with usual from a societal perspective. Methods A controlled clinical trial was performed Internal Medicine department general teaching hospital. All admitted patients using least one prescription drug were included. The consisted reconciliation, patient counselling...
What is the level of knowledge pharmacists concerning pain management and use opioids at end life, how do they cooperate with physicians?A written questionnaire was sent to a sample community hospital in Netherlands. The completed by 182 (response rate 45%).Pharmacists were aware most basic about opioids. Among respondents, 29% erroneously thought that life-threatening respiratory depression danger control, 38% believed preferred drug for palliative sedation. One three responding did not...