A5040165357- Birth, Development, and Health
- Moringa oleifera research and applications
- Fatty Acid Research and Health
- Natural Compound Pharmacology Studies
- Neurogenesis and neuroplasticity mechanisms
- Nuts composition and effects
- Ethnobotanical and Medicinal Plants Studies
- Drug-Induced Hepatotoxicity and Protection
- Phytochemistry and Biological Activities
- Iron Metabolism and Disorders
- Neurological Disease Mechanisms and Treatments
- Trace Elements in Health
- Garlic and Onion Studies
- Anesthesia and Neurotoxicity Research
- Alzheimer's disease research and treatments
- Nigella sativa pharmacological applications
- Chemotherapy-induced organ toxicity mitigation
- Aluminum toxicity and tolerance in plants and animals
- High Altitude and Hypoxia
- Phytoestrogen effects and research
- Humic Substances and Bio-Organic Studies
- Medicinal Plants and Bioactive Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Nephrotoxicity and Medicinal Plants
- Pharmacological Effects of Medicinal Plants
University of Ilorin
1970-2023
Adeleke University
1970-2017
University of Bahrain
2014
Madonna University
2012
Cuprizone-induced neurotoxicity has been employed to study the biology of remyelination in experimental models multiple sclerosis. This was aimed at determining role kolaviron, a biflavonoid from Garcinia kola, mitigating damaging effects cuprizone on behaviour and hippocampus. Twenty-four male albino mice aged 6-8 weeks were categorised into 4 equal groups: Group A (Control) received regular diet; B 200 mg/kg/d kolaviron addition their C 0.2% diet only, while D both diet. The treatment...
The objectives of the study were to determine placental weight as well factors associated with low and its impact on some anthropometrical parameters in newborn. A total 300 freshly delivered placentas examined this longitudinal-prospective study. Sobi Specialist Hospital, Alagbado, Ilorin, Surulere Medical Centre, Eruda, used for sample collections. Informed consent was obtained from patients institutional ethical clearance Kwara State Ministry Health (MOH/KS/ECI/777/82). Semistructured...
Recent evidences suggest that cerebellar degeneration may be associated with the development of Alzheimer's disease (AD). However, previous reports were mainly observational, lacking substantial characterization cellular and molecular features during AD progression.This study is aimed at characterizing cerebellum in rat models assessing corresponding neuroprotective mechanisms Garcinia biflavonoid complex (GBc).Male Wistar rats grouped treated alone or combination PBS (ad libitum)/day, corn...
We tested the hypothesis that Moringa oleifera impairs morphology and functions of kidney in rats.Twentyfour adult male Wistar rats were employed study.Rats Control Group I received physiological saline while Groups II -IV 250, 500 750 mg/kg bodyweight methanolic extract respectively for twenty one days.No behavioral anomalies observed -IV.Rats gained statistically significant increased experienced non-significant decreased during experimental procedure.(P≤0.05).No statistical differences...
Background: Exposure to tobacco has frequently been associated with adverse implications on many body organs and systems. Maternal smoking can influence fetal development, causing intrauterine growth restriction, preterm birth, or even death spontaneous abortion. Objectives: We investigated the effects of prenatal exposure nicotine prefrontal cortex in adolescent rats. Materials Methods: Twenty-four mature female Wistar rats were time mated grouped according Trimester into Control Treated...
Prenatal exposure to Marijuana (MJN) has been associated with various brain deficits. The main activity in marijuana, Δ9-Tetrahydrocannabinol (THC), crosses the placenta and affects fetal development. Despite this, marijuana remains a commonly abused substance among pregnant women. current study examined histological biochemical changes Superior Colliculus (SC) Lateral Geniculate Nucleus (LGN) rat brains prenatally exposed marijuana.Four groups of rats (n=5 rats/group) were smoke 10 g/kg at...
Cigarette smoke is known to be an important predisposing factor many diseased conditions, such as cardiovascular diseases, liver disease, atherosclerosis and other metabolic disorders. The aim of this study was examine the effects exposure from burnt cotton wool cigarette on plasma lipids, biochemistry histology, in adult Wistar rats. animals were divided into three groups Control A: exposed fresh atmospheric air; Group B: smoke; and, C, experiment lasted for 35 days. showed higher values...
Objectives: Mustard seeds, apart from being a culinary essential, have had medicinal applications dating back to the time of Hippocrates.It has in fact been once mentioned as greatest herb ever.We explored dose dependent effects crude aqueous extract Brassica nigra (Black mustard seeds) on prefrontal cortex adult Wistar rats.Methods: 20 female rats weighing an average 180±20 g were used.They split into 4 groups (n=5); Group A (received at 200 mg/kg body weight), B 100 C 50 and D distilled...
ABSTRACT Inversion is the regular position for bats at rest, but continuous inversion was expected to reverse gravity vector exposure from feet-ward head-ward and present hemodynamic challenges that induce remodeling of aorta. There paucity information regarding cardiovascular structural adaptations in engaged regulating cranial or caudal blood redistribution prolonged inversion. The aim this study determine aortic during Forty (40) were captured Iwo, Osun State, Nigeria randomly allocated...
Prenatal exposure of the foetus to chemical insults has implications on overall growth and development baby before after birth. This study examined effects prenatal nicotine morphology oligodendrocytes which are responsible for myelin in central nervous system, critical neurodevelopment. Twenty adult female Wistar rats were used study. Their oestrous cycle was determined by vaginal smearing, subsequently exposed male mating. The thereafter grouped into two each group further subdivided a...
Background The brain is built up during pregnancy. How it functions afterwards depends on how the expectant mother's diet nourishes it. Walnuts contain significant quantities of polyunsaturated fatty acids (PUFAs) and bioactive phytochemicals, which enhance health function even with advancing age. This study examined effects a walnut-enriched (WED) corticohippocampal histoarchitecture gene expression in rat offspring.Materials methods Twenty-eight female adult Wistar rats (n= 7) averaging...
Abstract Background : Early experiences at critical milestones significantly impact neurocognitive outcomes by altering brain development. Such issues can affect children’s academic achievement, disturb their behaviour, lower quality of life, and raise risk derangement in adulthood. These problems are linked to many possible neurotoxicants, including high ambient manganese (Mn) exposure. Walnuts possess levels ω-3 fatty acids a content potent phytochemicals, all which play an essential role...
This is to correct the author name “Omowumi F. Akinlosotu” Femi-Akinlosotu” in already published Volume 7, Issue 1 of Nigerian Journal Neuroscience.