José Pinto-Fraga

ORCID: 0000-0001-8179-9253
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About
Contact & Profiles
Research Areas
  • Ocular Surface and Contact Lens
  • Glaucoma and retinal disorders
  • Allergic Rhinitis and Sensitization
  • Corneal surgery and disorders
  • Peripheral Artery Disease Management
  • Contact Dermatitis and Allergies
  • Nutrition and Health in Aging
  • Cancer survivorship and care
  • Tryptophan and brain disorders
  • Cerebral Palsy and Movement Disorders
  • Multiple Sclerosis Research Studies
  • Corneal Surgery and Treatments
  • Stroke Rehabilitation and Recovery
  • Skin Protection and Aging
  • Stress Responses and Cortisol
  • Frailty in Older Adults
  • Effects of Vibration on Health
  • Gut microbiota and health
  • Advanced Glycation End Products research
  • Atherosclerosis and Cardiovascular Diseases
  • Vascular Malformations Diagnosis and Treatment
  • Galectins and Cancer Biology
  • Glioma Diagnosis and Treatment
  • Biochemical Acid Research Studies
  • Infant Development and Preterm Care

Universidad Europea Miguel de Cervantes
2018-2025

Universidad de Valladolid
2014-2024

Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
2015-2018

Centro de Investigación Biomédica en Red
2014-2016

Junta de Castilla y León
2016

Instituto de Salud Carlos III
2015

Abstract Aims This systematic review aims to evaluate and summarize findings from published meta-analyses on the effects of regular exercise in patients with peripheral arterial disease (PAD). The will assess impact functional parameters, health-related quality life, haemodynamic physical activity levels, adverse events, mortality. Methods results A search was performed PubMed, Web Science, Scopus, Cochrane Library databases (up May 2023) identify including randomized controlled trials that...

10.1093/eurjpc/zwad261 article EN European Journal of Preventive Cardiology 2023-08-23

ABSTRACT Objective: This study aimed to analyze the effect of a novel supervised exercise therapy (SET) program based on intermittent treadmill walking and circuit-based moderate-intensity functional training (MIFT) performance HRQoL in PAD patients. Design: All participants underwent 12-week SET that involved 15 30 minutes followed by 15-minute continued follow-up. Maximum distance (MWD), pain-free (PFWD), gait speed estimated peak oxygen uptake (peak VO2) were calculated through 6-minute...

10.1097/phm.0000000000002706 article EN American Journal of Physical Medicine & Rehabilitation 2025-01-06

Objectives: To evaluate the safety and efficacy of a new artificial tear containing 0.2% hyaluronic acid, as compared with 0.9% saline solution, in mild dry eye patients after 1-month use crossover study design washout periods. Methods: Overall, 16 were included. After week washout, every patient used experimental product (Visaid 0.2%) control (0.9% solution), each for month (3–8 drops daily). Both products preservative free. The percentage change following variables calculated analyzed:...

10.1097/icl.0000000000000236 article EN Eye & Contact Lens Science & Clinical Practice 2016-01-19

Purpose: To evaluate the safety and efficacy of a new 0.3% hyaluronic acid artificial tear compared with 0.9% saline solution (0.9% NaCl) in moderate-to-severe dry eye patients after 1 month's use. Methods: A total 16 were included this crossover study. After 1-week washout period, used experimental (Visaid 0.3%) or control NaCl), selected randomly, applying three to eight drops daily for month. another other same way. Percentage change (Δ Y ) was calculated analyzed (1) variables: visual...

10.1097/icl.0000000000000284 article EN Eye & Contact Lens Science & Clinical Practice 2016-05-28

Background: Resistance training (RT) has been recognized as a beneficial non-pharmacological intervention for multiple sclerosis (MS) patients, but its impact on neurodegeneration is not fully understood. This study aimed to investigate the effects of high-intensity RT muscle mass, strength, functional capacity, and axonal damage in MS patients. Methods: Eleven relapsing–remitting patients volunteered this within-subject counterbalanced study. Serum neurofilament light-chain (NfL)...

10.3390/healthcare12080837 article EN Healthcare 2024-04-15

It was hypothesized that tear protein biomarkers could predict the effects of topical steroid treatment and desiccating stress in patients with dry eye disease (DED). To test this concept, a randomized, double-masked, controlled clinical trial 41 conducted. The were treated topically either 0.1% fluorometholone (FML) or polyvinyl alcohol (PA). Tear samples collected using 1 μl glass capillaries at recruitment into study after 3-week period, both before 2 h exposure to stress, environment...

10.1016/j.jtos.2017.09.003 article EN cc-by-nc-nd The Ocular Surface 2017-09-14

To assess the interchangeability of tear osmolarity measurements between electrical impedance and freezing-point depression osmometers to analyze inter-eye variability measured with these in healthy subjects.Tear was using TearLab osmometer (OcuSense Inc., San Diego, CA) Fiske 210 microsample (Advanced Instruments Norwood, MA). We randomly selected one eye 50 subjects (29 women, 21 men; mean age, 33.16 ± 6.11 years) whether by were interchangeable. Both eyes 25 patients (15 10 34.32 6.37...

10.1097/opx.0000000000000817 article EN Optometry and Vision Science 2016-01-24

Questionnaires can provide unique information regarding the status of a condition from perspective patient. Contact lens (CL) discomfort (CLD) is subjectively reported by CL users; thus, updated and reliable questionnaires are needed.The objective this study was to design new questionnaire for identifying CLD, based on currently established CLD definition considered in Tear Film Ocular Surface Workshop.A survey characterise wearers created administered. Some items were selected focus group...

10.1080/08164622.2021.1896945 article EN Clinical and Experimental Optometry 2021-03-18

In recent years, accumulating evidence from preclinical and clinical studies consistently indicated that physical activity/exercise plays a crucial role in reducing the incidence recurrence of various malignancies, by exerting beneficial modulation cancer hallmarks.Moreover, activity is suggested to attenuate certain adverse effects anticancer therapy, including reduction cardiovascular toxicity symptoms related depression anxiety, among others, while preserving muscular strength.In case...

10.7150/jca.88559 article EN cc-by-nc Journal of Cancer 2023-12-05

Objectives: Determining the changes in symptomatology suffered by dry eye disease (DED) patients after an intervention is difficult because there only one validated questionnaire specifically designed to measure these and it somewhat complex. This work uses a simplified evaluate DED-related symptoms. Methods: A new based on global rating of change scale was designed. The Change Dry Eye Symptoms Questionnaire (CDES-Q) consists 2 questions: CDES-Q1 asks for symptoms (“better,” “same,” or...

10.1097/icl.0000000000000693 article EN Eye & Contact Lens Science & Clinical Practice 2020-02-24

Physical activity, sports and risk of atrial fibrillation: umbrella review meta-analyses Pedro L Valenzuela, Valenzuela Systems Biology Department, University Alcalá, SpainDepartment Sport Health, Spanish Agency for Health Promotion in Sports (AEPSAD), Spain Search other works by this author on: Oxford Academic Google Scholar Alejandro Santos-Lozano, Santos-Lozano i+HeALTH, Department Sciences, European Miguel de Cervantes, SpainResearch Institute the Hospital 12 Octubre (‘imas12’), Javier S...

10.1177/2047487320923183 article EN European Journal of Preventive Cardiology 2020-05-16
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