Hans Erik Heier

ORCID: 0000-0001-8180-0082
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About
Contact & Profiles
Research Areas
  • Blood groups and transfusion
  • Blood transfusion and management
  • Blood donation and transfusion practices
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Erythrocyte Function and Pathophysiology
  • Trauma and Emergency Care Studies
  • Monoclonal and Polyclonal Antibodies Research
  • Abdominal Trauma and Injuries
  • Glycosylation and Glycoproteins Research
  • Iron Metabolism and Disorders
  • Lymphoma Diagnosis and Treatment
  • Organ Donation and Transplantation
  • Hepatitis B Virus Studies
  • Immune Cell Function and Interaction
  • Trace Elements in Health
  • Hemoglobinopathies and Related Disorders
  • Education, Healthcare and Sociology Research
  • Heavy Metal Exposure and Toxicity
  • Biosensors and Analytical Detection
  • Pancreatitis Pathology and Treatment
  • Healthcare cost, quality, practices
  • Hepatitis C virus research
  • Caveolin-1 and cellular processes
  • Gallbladder and Bile Duct Disorders
  • Immunodeficiency and Autoimmune Disorders

Pharmalog (Germany)
2025

National Blood Transfusion Service
2024

University of Oslo
2011-2024

Octapharma (Austria)
2020

Norwegian Armed Forces
2010-2016

Oslo University Hospital
2000-2015

Haukeland University Hospital
2014

University of Bergen
2014

Institutt for Eksperimentell Medisinsk Forskning
2012

St Olav's University Hospital
2010

Background and Objectives The aim of this study was to establish which motivational socio‐demographic factors are important for the development a long‐term commitment as voluntary, non‐remunerated blood donor. Study Design Methods A cross‐sectional sample survey active donors in Oslo, Norway, conducted. Donors filled self‐administered questionnaire during donation. Data on motivation were analysed using factor analysis. Results donors’ characteristics found be similar those population whole....

10.1111/j.1423-0410.2005.00706.x article EN Vox Sanguinis 2005-10-27

Women are under-represented among long-term blood donors. Reasons for this were sought in the donor pool of Blood Bank Oslo, Norway, which comprises only voluntary, non-remunerated donors and has a high degree stability.Three sources data analyzed: (1) subsequent six-year donation patterns 17 812 who donated at least once 1999; (2) reasons pre-donation deferral 484 prospect 2004; (3) deferrals absence during 6.5-year period, retrieved from follow-up study 1029 took part questionnaire on...

10.1111/j.1423-0410.2009.01267.x article EN Vox Sanguinis 2009-10-06

Incidences of infections with Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2) are still high and treatment guidelines lack specific recommendations for outpatients Coronavirus-induced disease 2019 (COVID-19). Phytomedicine ELOM-080, an enhancer mucociliary clearance (MCC), showed benefits as add-on therapy in hospitalised COVID-19 patients. This randomised, double-blind, placebo-controlled proof-of-concept study investigated whether mild to moderate acute symptomatic would...

10.1007/s12325-024-03093-4 article EN cc-by-nc Advances in Therapy 2025-01-15

Abstract Sera from 50 patients with Hodgkin's disease, 78 non‐Hodgkin non‐leukemic malignant lymphomas, and 75 different types of solid tumors were investigated for the presence immune complexes using ( 125 I) C1q‐binding test. All untreated. An increased serum activity was found in 22% 35.9% lymphoma 37.3% tumors. The material detected patients' sera had properties similar to those complexes. On sucrose density gradient it sedimented as a 10‐30 s material. It contained IgG which dissociated...

10.1002/ijc.2910200611 article EN International Journal of Cancer 1977-12-15

Reasons for predonation deferral of young potential donors and prospects recruiting retaining people (age 18-29) as voluntary blood were studied.Three different sources data analysed: (i) the subsequent donation history 2057 who started their career at Blood Bank Oslo (BBO) in 1999, age gender all new accepted BBO 2004 was retrieved from electronic files; (ii) on reasons deferral, deferred prospect obtained original screening questionnaires; (iii) results a national telephone survey general...

10.1111/j.1423-0410.2007.01004.x article EN Vox Sanguinis 2007-12-07

Background and objectives Severe anaemia is an important cause of mortality in developing countries. However, few studies have explored the use possibilities for blood transfusion services. The aims this study are to explore services at a hospital sub‐Saharan Africa assess quality according WHO guidelines. Materials methods Patient age, gender, haemoglobin (Hb) level, diagnosis, department replacement donations were recorded all transfusions administered district Malawi January 2010....

10.1111/j.1423-0410.2012.01628.x article EN Vox Sanguinis 2012-07-06

BACKGROUND: Keeping waiting time at blood donation short is important for making a good experience the donors and hence to motivate repeat donations. At Blood Bank of Oslo, fixed appointments are used, few arrive without appointments. On average, 59 percent scheduled arrive, but day‐to‐day variations large. Methods predicting number that will on given day would be valuable in reducing times. STUDY DESIGN AND METHODS: Information about candidate explanatory variables was collected all made...

10.1111/j.1537-2995.2004.04167.x article EN Transfusion 2005-01-19

Twenty-one young, splenectomized, healthy individuals (S group) and ten (K were vaccinated with a 14-valent pneumococcal polysaccharide vaccine. All in the S group splenectomized due to abdominal trauma. IgM IgG antibodies against each of 14 serotypes determined by enzyme-linked immunosorbent assay. Serum concentrations measured radial immunodiffusion. The mean prevaccination antibody level was lower than K for most serotypes. total serum considerably reduced group. Vaccination induced...

10.1111/j.1699-0463.1984.tb00046.x article EN Acta Pathologica Microbiologica Scandinavica Series C Immunology 2009-08-15

The phenomenon of spontaneous nonimmune rosette formation between human lymphocytes and sheep erythrocytes has been investigated with respect to its sensitivity mechanical trauma It is shown that tin percentage rosettes depends on the strength force used resuspend lymphocyte‐erythrocyte pellet alter incubation but not duration resuspension procedure Differences patients chronic lymphatic leukemia persons normal percentages T are clearly when weak a relatively strong Practical theoretical...

10.1111/j.1365-3083.1974.tb01302.x article EN Scandinavian Journal of Immunology 1974-10-01

The purpose of this study was to explore the molecular basis p phenotype by analysis recently cloned 4-alpha-galactosyltransferase gene responsible for synthesis Pk (Gb3) antigen.Forty samples from individuals eight different nationalities were investigated serologic methods and DNA sequencing gene.Ten Pk-null alleles, which 6 are novel, encountered. 29 Swedes homozygous M183K or G187D, with former as predominant allele. Three Israelis a single-nucleotide deletion at codon 219 that shifts...

10.1046/j.1537-2995.2003.00425.x article EN Transfusion 2003-06-20

At the 2013 Traumatic Hemostasis and Oxygenation Research Network's Remote Damage Control Resuscitation symposium, a panel of senior blood bankers with both civilian military background was invited to discuss their willingness ability supply prehospital plasma for resuscitation massively bleeding casualties comment on optimal preparations such situations. Available evidence indicates that use may improve remote damage control resuscitation, although level I is lacking. This practice well...

10.1097/shk.0000000000000144 article EN Shock 2014-02-04

Background: The prevalence of hereditary hemochromatosis in Norway is one the highest reported world. However, clinical presentation patients with seems to be different compared recent studies elsewhere. aim this study was investigate community hospital and C282Y mutation. Methods: One hundred twenty were consecutively admitted medical department Oslo. Serum transferrin ferritin concentrations measured all patients, a percutaneous liver biopsy obtained 108 120 (90%) patients. Stainable iron...

10.1080/003655200453665 article EN Scandinavian Journal of Gastroenterology 2000-01-01

Silver enhancement of immunogold-labeled cells was carried out to increase the applicability colloidal gold probes for visualization in backscatter electron imaging (BEI) mode a scanning microscope. Optimum conditions were established single particle discrimination and differential counting labeling density at low magnifications. Red blood double-labeled with 15 + 40 nm 5 20 silver-enhanced 6 min min, respectively, which times both pairs labels increased about 25 50 nm. The still appeared...

10.1002/jemt.1060110203 article EN Journal of Electron Microscopy Technique 1989-02-01

Abstract Scanning immune electron microscopy using a monoclonal anti‐A antibody which reacts with all type A oligosaccharide chains revealed antigens on less than 5% of m and el cells, some showed extremely strong labelling. This explains why cells can absorb significant amounts without being agglutinated. 3 may be heterogenous subgroup, since were found 82 58%, respectively, the 2 individuals. 75% or more x cells. In many weak individuals A‐positive are apparently best detected if an is...

10.1111/j.1423-0410.1994.tb00315.x article EN Vox Sanguinis 1994-04-01

BACKGROUND: Blood banks ensure the safety of blood components by testing them for a set known infectious agents and careful selection donors based on self‐administered questionnaire an interview. The purpose this study is to describe risk behavior sexually transmitted diseases in Norwegian donors. STUDY DESIGN AND METHODS: A survey sexual habits 5,859 capital Norway was performed using anonymous questionnaires. results were compared with previous 10,000 randomly selected subjects aged 18 60...

10.1046/j.1537-2995.2001.41121480.x article EN Transfusion 2001-12-01

Background and objectives. In fresh blood, tissue hypoxia increases microcirculatory acidosis, which enhances erythrocyte O2 unloading the amount of available O2. Storage erythrocytes HbO2 affinity reduces unloading. We examined development change during a period 5 weeks storage by present blood bank standards, investigated to what extent acidosis offsets change. Materials methods. Blood from volunteer donors was processed stored as concentrates (EC). At 2–5 day intervals, EC were drawn bags...

10.3109/00365513.2011.565366 article EN cc-by Scandinavian Journal of Clinical and Laboratory Investigation 2011-04-08

The North Atlantic Treaty Organization (NATO) Blood Panel exists to promote interoperability of transfusion practice between NATO partners. However, it has served as an important forum for the development prehospital and in austere environment. There are synergies with trauma hemostasis oxygen research community especially areas innovation research. Four presentations summarized together a review some scientific principles. past decade already seen significant changes early support....

10.1111/trf.13489 article EN Transfusion 2016-04-01
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