A5053010495- Trauma and Emergency Care Studies
- Abdominal Trauma and Injuries
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Injury Epidemiology and Prevention
- Nitric Oxide and Endothelin Effects
- Trauma Management and Diagnosis
- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Abdominal Surgery and Complications
- Cardiac Ischemia and Reperfusion
- Traffic and Road Safety
- Automotive and Human Injury Biomechanics
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic and Acetabular Injuries
- Renal function and acid-base balance
- Intestinal and Peritoneal Adhesions
- Disaster Response and Management
- Cardiac Imaging and Diagnostics
- Nursing Roles and Practices
- Urological Disorders and Treatments
- Heart Failure Treatment and Management
- Hemodynamic Monitoring and Therapy
- Mechanical Circulatory Support Devices
- Appendicitis Diagnosis and Management
- Abdominal vascular conditions and treatments
Oslo University Hospital
2015-2025
University of Oslo
2004-2025
Indianapolis Zoo
2024
University of Baltimore
2024
West Los Angeles College
2024
Jackson College
2024
Kaiser Permanente Fontana Medical Center
2024
Ann Arbor Center for Independent Living
2024
University of Houston
2024
Charlottesville Medical Research
2024
Contemporary trauma resuscitation prioritizes control of bleeding and uses major haemorrhage protocols (MHPs) to prevent treat coagulopathy. We aimed determine whether augmenting MHPs with Viscoelastic Haemostatic Assays (VHA) would improve outcomes compared Conventional Coagulation Tests (CCTs).This was a multi-centre, randomized controlled trial comparing in patients who received empiric MHPs, augmented by either VHA or CCT-guided interventions. Primary outcome the proportion subjects who,...
Developing pragmatic data-driven algorithms for management of trauma induced coagulopathy (TIC) during hemorrhage viscoelastic hemostatic assays (VHAs).Admission data from conventional coagulation tests (CCT), rotational thrombelastometry (ROTEM) and thrombelastography (TEG) were collected prospectively at 6 European centers 2008 to 2013.To identify significant VHA parameters capable detecting TIC (defined as INR > 1.2), hypofibrinogenemia (< 2.0 g/L), thrombocytopenia 100 x10/L), univariate...
Background Trauma hemorrhage induces a coagulopathy with high associated mortality rate. The Implementing Treatment Algorithms for the Correction of Induced Coagulopathy (ITACTIC) randomized trial tested two goal-directed treatment algorithms coagulation management: one guided by conventional tests and viscoelastic hemostatic assays (viscoelastic). lack difference in 28-day led authors to hypothesize that coagulopathic patients received insufficient correct coagulopathy. Methods During...
Abstract Circulating levels of the endothelium-derived vasoconstrictor peptide endothelin-1 (ET-1) are increased in association with myocardial ischemia and infarction. The present study investigates whether ET-1 is synthesized produced locally ischemic heart. Sixteen pigs were divided into three groups. In first group, left anterior descending coronary artery was occluded for 90 minutes, followed by 150 minutes reperfusion (group A, n=8). Two additional groups subjected to B, n=4) or 240 C,...
Pyloric stenosis is one of the most common reasons for surgery in infants. Standard practice has traditionally been to gradually increase feeding volumes postoperatively. In 2018, Oslo University Hospital, Ullevål introduced ad libitum following pyloric stenosis. We aimed investigate whether new regimen affected frequency postoperative complications and length hospital stay. A retrospective study children who underwent at period 2004-2021. Data were collected on sex, age, birth weight,...
Abstract Background The combined effects of balanced transfusion ratios and use procoagulant antifibrinolytic therapies on trauma-induced exsanguination are not known. aim this study was to investigate the effect ratios, tranexamic acid products containing fibrinogen outcome injured patients with bleeding. Methods A prospective multicentre observational performed in six level 1 trauma centres. Injured who received at least 4 units red blood cells (RBCs) were analysed divided into groups...
Background The recommended treatment for cervical spinal cord injury (cSCI) is surgical decompression and stabilization within 24 h after injury. aims of the study were to estimate our institutional compliance with this recommendation identify potential factors associated delay. Methods Population-based retrospective database patients operated cSCI in 2015–2022 South-East Norway Health Region (3.1 million inhabitants). Data extracted demographics, description, management timeline, place...
Abstract Background Previous studies have demonstrated that the trauma population has needs for rehabilitation services are best provided in a continuous and coordinated way. The discharge destination after acute care is second step to ensuring quality of care. There lack knowledge regarding factors associated with overall population. This paper aims identify sociodemographic, geographical, injury-related following at centers patients moderate-to-severe traumatic injuries. Methods A...
Objective: Motor vehicle collisions (MVCs) are a leading cause of death and acute disability among young adults worldwide. We performed prospective study drivers involved in severe MVCs, investigating the critical events up to collision with an emphasis on driver-related factors culpability. Methods: A was conducted southeastern Norway all younger than 25 years who were high-energy MVCs resulting immediate hospitalization during 2013–2016. Collision investigators evaluated exterior interior...
Nitric oxide plays an important role in the regulation of basal renal blood flow. This study was performed to examine whether selective inhibiti± nitric synthesis affects renin release vivo . Accordingly, six barbiturate‐anaesthetized dogs examined before and after intrarenal infusion inhibitor synthesis, N G ‐nitro‐ l ‐arginine (NOARG). NOARG infused into artery yield a arterial concentration 0.4 μ mol ml ‐1 did not change systemic pressure glomerular filtration rate, but reduced flow by 26...
To describe the use of radiology in emergency department (ED) a trauma centre during mass casualty incident, using minimum acceptable care (MAC) strategy which CT was restricted to potentially severe head injuries.We retrospectively studied initial imaging on patients triaged following twin terrorist attacks Norway 22 July 2011.Nine from explosion and 15 shooting were included. Fourteen had an Injury Severity Score >15. During first h, 22/24 underwent ED. All gunshot plain films taken ED,...
The importance of nitric oxide (NO) in coronary blood flow (CBF) regulation was examined anesthetized pigs. NO synthesis inhibited by intracoronary infusion NG-monomethyl-L-arginine (L-NMMA) or NG-nitro-L-arginine (L-NNA). L-NMMA (30 mumol/min) reduced CBF (Doppler flowmetry) 16.3% (13.1-20.2%; P < 0.001) and L-NNA 16.1% (13.9-18.9%; 0.001). During blockade, myocardial oxygen consumption unaltered as an increase extraction occurred due to a partial pressure saturation from the anterior...
Triage and interhospital transfer are central to trauma systems. Few studies have addressed transferred patients. This study investigated transfers of variable distances OUH (Oslo University Hospital, Ullevål), one the largest centres in Europe. Patients included registry from 2001 2008 were study. Demographic, injury, management outcome data abstracted. grouped according distance: ≤20 km, 21-100 km > 100 km. Of 7.353 patients, 5.803 admitted directly, 1.550 transferred. The number per year...
Report a nationwide epidemic of Shiga toxin-producing E. coli (STEC) O103:H25 causing hemolytic uremic syndrome (D+HUS) in children.Description clinical presentation, complications and outcome outbreak.Ten children (median age 4.3 years) developed HUS during the outbreak. One these was presumed to be part outbreak without microbiological proof. Eight patients were oligoanuric need dialysis. Median for dialysis 15 days; one girl did not regain renal function received kidney transplant. Four...