A5073020223- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Injury Epidemiology and Prevention
- Advanced Neuroimaging Techniques and Applications
- Hip and Femur Fractures
- Family and Patient Care in Intensive Care Units
- Nursing Roles and Practices
- Acute Ischemic Stroke Management
- Trauma Management and Diagnosis
- Healthcare Systems and Public Health
- Childhood Cancer Survivors' Quality of Life
- Global Health Workforce Issues
- Vestibular and auditory disorders
- Disaster Response and Management
- Child and Adolescent Health
- Cerebrospinal fluid and hydrocephalus
Oslo University Hospital
2014-2024
University of Oslo
2017
Abstract Objectives The study describes functional outcomes and health‐related quality of life ( HRQL ) in patients with traumatic brain injury TBI 20 years postinjury. Materials Methods Forty‐four survivors who acquired moderate severe during 1995–1996 were followed 10 Outcomes Glasgow Outcome Scale Extended GOSE ), Community Integration Questionnaire CIQ SF ‐36 questionnaire ‐36). Multiple regressions performed to examine the relationship between follow‐up measurements, controlling for...
Aims: Based on important predictors, global functional outcome after traumatic brain injury (TBI) may vary significantly over time. This study sought to: (1) describe changes in the Glasgow Outcome Scale-Extended (GOSE) score survivors of moderate to severe TBI, (2) examine longitudinal GOSE trajectories up 10 years injury, and (3) investigate predictors these based socio-demographic characteristics. Methods: Socio-demographic characteristics 97 TBI aged 16-55 were recorded at baseline. was...
Abstract Background Traumatic brain injury (TBI) represents a financial burden to the healthcare system, patients, their families and society. Rehabilitation interventions with potential for reducing costs associated TBI are demanded. This study evaluated cost-effectiveness of randomized, controlled, parallel group trial that compared effectiveness combined cognitive vocational intervention treatment as usual (TAU) on outcomes. Methods One-hundred sixteen participants mild-to-moderate were...
Objective . To predict return to work (RTW) at 12 months for patients who either were sick-listed or risk be with persistent postconcussion symptoms (PCS) six eight weeks after injury. Method A prospective cohort study of 151 mild traumatic brain injury (MTBI) admitted consecutively outpatient clinics two University Hospitals in Norway. The was conducted as part a randomised clinical trial. Injury characteristics obtained from the medical records. Sick leave data one year before MTBI...
Identifying patients at risk of poor outcome after mild traumatic brain injury (MTBI) is essential to aid prognostics and treatment. Diffuse axonal (DAI) may be the primary pathologic feature MTBI but normally not detectable by conventional imaging technology. This lack sensitivity clinical techniques has impeded a pathophysiologic understanding long-term cognitive emotional consequences MTBI, which often remain unnoticed are attributed factors other than injury. Diffusion tensor (DTI)...
To evaluate the efficacy of a multidisciplinary outpatient follow-up programme compared to by general practitioner for patients being at-risk or sick-listed with persistent post-concussion symptoms two months after mild traumatic brain injury.Randomised controlled trial.One hundred fifty-one patients, 16-56 years.Multidisciplinary rehabilitation individual contacts and psycho-educational group intervention at clinics examination. Primary outcome was sustainable return-to-work first year...
Returning to work is often a primary rehabilitation goal after traumatic brain injury (TBI). However, the evidence base for treatment options regarding return (RTW) and stable maintenance remains scarce. This study aimed examine effect of combined cognitive vocational intervention on work-related outcomes mild-to-moderate TBI. In this study, we compared 6 months compensatory training supported employment (CCT-SE) with as usual (TAU) in randomised controlled trial time RTW, percentage, hours...
Abstract Background Previous studies have demonstrated that the trauma population has needs for rehabilitation services are best provided in a continuous and coordinated way. The discharge destination after acute care is second step to ensuring quality of care. There lack knowledge regarding factors associated with overall population. This paper aims identify sociodemographic, geographical, injury-related following at centers patients moderate-to-severe traumatic injuries. Methods A...
Accurate outcome prediction models for patients with mild traumatic brain injury (MTBI) are key prognostic assessment and clinical decision-making. Using multivariate machine learning, we tested the unique added predictive value of (1) magnetic resonance imaging (MRI)-based morphometric volumetric characterization at 4-week postinjury (2) demographic, preinjury, injury-related, variables on 12-month outcomes, including global functioning level, postconcussion symptoms, mental health in...
To investigate longitudinal changes in cortical and subcortical volumes patients with mild traumatic brain injury (MTBI) to evaluate whether such were associated self-reported post-concussive symptoms, global functional outcomes neuropsychological functioning.This was a prospecitve, cohort study of complicated (i.e presence intracranial abnormalities on the day CT) uncomplicated MTBI (i.e, absence abnormalities). Magnetic resonance imaging (MRI) performed at approximately 4 weeks 12 months....
Abstract Patients with physical traumatic injuries frequently require long-term rehabilitation services. To strengthen services in the post-acute phase, we need to assess characteristics of this population and their healthcare needs community. This brief report summarizes frequency unmet community-based during first year after moderate severe trauma. Additionally, associations between sociodemographic, injury severity factors were examined. Data from a prospective multicenter cohort study...
The High-Level Mobility Assessment Tool (HiMAT) was developed to quantify balance and mobility problems after traumatic brain injury (TBI). Measurement properties of the HiMAT have not been tested in mild TBI (MTBI) population.The aim this study examine reliability, validity, responsiveness a sample MTBI population.A cohort, pretest-posttest, comparison conducted.Ninety-two patients (69% men, 31% women) with mean age 37.1 years (SD=13.8) Glasgow Coma Scale score 14.7 (SD=0.7) were recruited...
This study sought to identify potential differing clinical characteristics between patients with a mild traumatic brain injury (MTBI) who attended planned follow-up session and not. investigated whether attendance for service 2-months after could be related return-to-work (RTW) 1-year later.Prospective cohort of 343 MTBI admitted consecutively the Department Neurosurgery in 2009-2011. Demographic data were obtained from hospital files about sick leave The Norwegian Labour Welfare Service....
To investigate the associations between dizziness-related disability after mild- moderate Traumatic Brain Injury (TBI) and personal factors, injury-related factors post-injury functioning using International Classification of Functioning, Disability Health (ICF) as a framework.Baseline assessments for Randomised Controlled Trial (RCT) were obtained 65 patients (mean age 39.2 years; SD 12.9 70.8% women) who had dizziness reduced balance 2-6 months injury. The severity brain injury, physical...
Despite existing guidelines for managing mild traumatic brain injury (mTBI), evidence-based treatments are still scarce and large-scale studies on the provision impact of specific rehabilitation services needed. This study aimed to describe patients after complicated uncomplicated mTBI investigate factors associated with functional outcome, symptom burden, TBI-specific health-related quality life (HRQOL) up six months injury.Patients (n = 1379) from Collaborative European NeuroTrauma...
Substantial variance exists in outcomes after mild traumatic brain injury (MTBI), and these differences are not fully explained by characteristics or severity. Genetic factors likely to play a role this variance.The aim of study was examine associations between the apolipoprotein (APOE)-ε4 allele memory measures at two months post-MTBI evaluate whether subjective cognitive affective symptoms were associated with APOE-ε4 status. Based on previous research, it hypothesized that carriers would...
This study aims to evaluate the global functional outcomes after moderate-to-severe traumatic injury at 6 and 12 months examine sociodemographic injury-related factors that predict these outcomes. A prospective cohort was conducted in which trauma patients of all ages with a New Injury Severity Score > 9 who were discharged alive from two regional centres Norway over one-year period (2020) included. The Glasgow Outcome Scale Extended (GOSE) score used analyse Regression analyses performed...
Aims: Knowledge regarding the most effective return to work (RTW) approaches after traumatic brain injury (TBI) is lacking. This trial aimed compare effectiveness of a combined cognitive and vocational intervention treatment as usual (TAU) on RTW stability TBI. Methods: We performed parallel-group randomized controlled (RCT) at TBI outpatient clinic Oslo University Hospital (OUH), Norway. Patients with history mild-to-moderate (n = 116) aged 18-60 were (1:1) by an independent investigator...
Objective: To evaluate adherence to 3 central operational recommendations for acute rehabilitation in the Norwegian trauma plan.Methods: A prospective multi-centre study of 538 adults with moderate and severe New Injury Severity Score > 9.Results: Adherence first recommendation, assessment by a physical medicine physician within 72 h following admission intensive care unit (ICU) at centre, was documented 18% patients. second early unit, 72% those ≥ 2 days ICU stay. Predictors were length...
Objective: To describe the needs for subacute inpatient rehabilitation and community-based healthcare services, rehabilitation, social support in patients with moderate-to-severe traumatic injury first 6 months post-injury. Further, to explore associations between sociodemographic clinical characteristics unmet needs. Design: Multicentre prospective cohort study. Subjects: Of 601 persons (75% males), mean (standard deviation) age 47 (21) years, admitted trauma centres 2020 injury, 501...
: Traumatic injury is a leading cause of death and disability in children young adults. There lack evidence-based literature guidelines on supporting families after severe child injury. This study aimed to assess the family needs factors associated with those needs.
Objective: This study compared cortical and sub-cortical volumes between patients with complicated (i.e. presence of intracranial abnormality on the day-of-injury CT) uncomplicated absence abnormality) mild traumatic brain injury (MTBI) 4 weeks post-injury. The hypothesized regionally decreased reduced thickness in MTBIs MTBI.Methods: was part a larger 2 years cohort MTBI. Baseline clinical magnetic resonance imaging (MRI) data were for those It identified 168 MTBI (90 78 complicated), aged...
Traumatic injuries, defined as physical injuries with sudden onset, are a major public health problem worldwide. There is paucity of knowledge regarding rehabilitation needs and service provision for patients moderate trauma, even if research on spectrum specific available.This study aims to describe the prevalence needs, provided services, functional outcomes across all age groups, levels injury severity, geographical regions in first year after trauma. Direct indirect costs will also be...