Lars Wik

ORCID: 0000-0002-5774-4313
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About
Contact & Profiles
Research Areas
  • Cardiac Arrest and Resuscitation
  • Trauma Management and Diagnosis
  • Mechanical Circulatory Support Devices
  • Trauma and Emergency Care Studies
  • Respiratory Support and Mechanisms
  • Disaster Response and Management
  • Heart Rate Variability and Autonomic Control
  • Non-Invasive Vital Sign Monitoring
  • Cardiac electrophysiology and arrhythmias
  • Healthcare Technology and Patient Monitoring
  • Emergency and Acute Care Studies
  • Injury Epidemiology and Prevention
  • ECG Monitoring and Analysis
  • Cardiac Ischemia and Reperfusion
  • Hemodynamic Monitoring and Therapy
  • Airway Management and Intubation Techniques
  • Traumatic Brain Injury Research
  • Thermal Regulation in Medicine
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiovascular Effects of Exercise
  • Sepsis Diagnosis and Treatment
  • Restraint-Related Deaths
  • Family and Patient Care in Intensive Care Units
  • EEG and Brain-Computer Interfaces
  • Cardiovascular Function and Risk Factors

Oslo University Hospital
2015-2024

University of Oslo
2006-2021

University of the Basque Country
2020-2021

Emory University
2020

Lars Research Institute
2011-2019

Institutt for Eksperimentell Medisinsk Forskning
2001-2010

Medtronic (United States)
2010

Stiftelsen Norsk Luftambulanse
1995-2008

Stavanger University Hospital
2004-2008

University of Stavanger
2008

First, I like to thank my supervisors, Petter Andreas Steen and Lars Wik, who invited me into their unique collaboration gave the opportunity experience a wonderful time at Institute really get absorbed in this exciting clinically relevant field.In very own way, both have supported been available for questions, opinions, discussions all times.Their enthusiasm is commendable network of contacts impressive -both these qualities are so valuable anyone entering field science.Over last few years...

10.1001/jama.293.3.299 article EN JAMA 2005-01-18

Context Defibrillation as soon possible is standard treatment for patients with ventricular fibrillation. A nonrandomized study indicates that after a few minutes of fibrillation, delaying defibrillation to give cardiopulmonary resuscitation (CPR) first might improve the outcome. Objective To determine effects CPR before on outcome in fibrillation and response times either up or longer than 5 minutes. Design, Setting, Patients Randomized trial 200 out-of-hospital Oslo, Norway, between June...

10.1001/jama.289.11.1389 article EN JAMA 2003-03-19

<h3>Context</h3>Intravenous access and drug administration are included in advanced cardiac life support (ACLS) guidelines despite a lack of evidence for improved outcomes. Epinephrine was an independent predictor poor outcome large epidemiological study, possibly due to toxicity the or cardiopulmonary resuscitation (CPR) interruptions secondary establishing intravenous line administration.<h3>Objective</h3>To determine whether removing from ACLS protocol would improve survival hospital...

10.1001/jama.2009.1729 article EN JAMA 2009-11-24

Early defibrillation is considered the most important factor for restoring spontaneous circulation in cardiac arrest patients with ventricular fibrillation. Recent studies have shown that, after prolonged fibrillation, rates of return (ROSC) and survival are improved if delayed so that CPR can be given first. To examine whether improves myocardial readiness defibrillation, we analyzed causes changes predictors success calculated from fibrillation waveform.ECG recordings were retrieved 105 an...

10.1161/01.cir.0000133323.15565.75 article EN Circulation 2004-06-22

There is a need to monitor the heart rhythm in resuscitation improve treatment quality. Resuscitation rhythms are categorized into: ventricular tachycardia (VT), fibrillation (VF), pulseless electrical activity (PEA), asystole (AS), and pulse-generating (PR). Manual annotation of time-consuming infeasible for large datasets. Our objective was develop ECG-based algorithms retrospective automatic classification cardiac rhythms.The dataset consisted 1631 3-s ECG segments with clinical...

10.1109/tbme.2017.2688380 article EN IEEE Transactions on Biomedical Engineering 2017-03-30

Early recognition of ventricular fibrillation (VF) and electrical therapy are key for the survival out-of-hospital cardiac arrest (OHCA) patients treated with automated external defibrillators (AED). AED algorithms VF-detection customarily assessed using Holter recordings from public electrocardiogram (ECG) databases, which may be different ECG seen during OHCA events. This study evaluates data both recordings. ECG-segments 4-s 8-s duration were analyzed. For each segment 30 features...

10.1371/journal.pone.0159654 article EN cc-by PLoS ONE 2016-07-21

Early defibrillation by an automated external defibrillator (AED) is key for the survival of out-of-hospital cardiac arrest (OHCA) patients. ECG feature extraction and machine learning have been successfully used to detect ventricular fibrillation (VF) in AED shock decision algorithms. Recently, deep architectures based on 1D Convolutional Neural Networks (CNN) proposed this task. This study introduces a architecture 1D-CNN layers Long Short-Term Memory (LSTM) network detection VF. Two...

10.1371/journal.pone.0216756 article EN cc-by PLoS ONE 2019-05-20

Physiology-guided cardiopulmonary resuscitation (CPR) offers the potential to optimize and enable early prognosis. Physiology-Guided CPR was one of six focus topic for Wolf Creek XVII Conference held on June 14–17, 2023 in Ann Arbor, Michigan, USA. International thought leaders scientists field cardiac arrest from academia industry were invited. Participants submitted via online survey knowledge gaps, barriers translation research priorities each topic. Expert panels used results their own...

10.1016/j.resplu.2024.100589 article EN cc-by-nc-nd Resuscitation Plus 2024-02-29

Background: The importance of ventilations after cardiac arrest has been much debated recently and eliminating mouth‐to‐mouth for bystanders suggested as a means to increase bystander cardiopulmonary resuscitation (CPR). Standard basic life support (S‐BLS) is not documented be superior continuous chest compressions (CCC). Methods: Retrospective, observational study all non‐traumatic patients older than 18 years between May 2003 December 2006 treated by the community‐run emergency medical...

10.1111/j.1399-6576.2008.01723.x article EN Acta Anaesthesiologica Scandinavica 2008-07-09
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