A5091243645- Immunodeficiency and Autoimmune Disorders
- Mycobacterium research and diagnosis
- Pediatric health and respiratory diseases
- Tuberculosis Research and Epidemiology
- Advanced Chemical Sensor Technologies
- Tracheal and airway disorders
- Cystic Fibrosis Research Advances
- Immune Cell Function and Interaction
- Exercise and Physiological Responses
- Digestive system and related health
- Asthma and respiratory diseases
- Congenital Diaphragmatic Hernia Studies
- Diabetes and associated disorders
- Infant Health and Development
- Genetics and Neurodevelopmental Disorders
- Herbal Medicine Research Studies
- Adrenal Hormones and Disorders
- Complex Systems and Time Series Analysis
Shahid Beheshti University of Medical Sciences
2019-2022
Shahid Beheshti University
2020-2021
Masih Daneshvari Hospital
2019-2020
Inborn errors of immunity (IEIs) are rare inherited disorders with a broad spectrum manifestations. Here, we aimed to delineate the atopy burden in cohort patients IEIs.313 IEIs were enrolled study within 9-years period, and data collected via questionnaire. All statistical analyses performed using SPSS software (v. 25.0, Chicago, IL, USA). The significance level was set at p < 0.05.Overall, 51 out 313 (16.3%) identified have atopic Food allergy detected 34 (10.2%), dermatitis 21 (6.7%), as...
Inborn errors of immunity (IEIs) are a group congenital diseases caused by genetic defects in the development and function immune system. The involvement respiratory tract is one most common presentations IEIs.Overall, 117 patients with diagnosed IEIs were followed-up within 8 years at National Research Institute Tuberculosis Lung Diseases (NRITLD). Demographic, clinical, laboratory data collected questionnaire. Pulmonary test (PFT), chest X-ray (CXR), high-resolution computed tomography...
LPS-responsive beige-like anchor protein (LRBA) deficiency is a monogenic primary immunodeficiency characterized by heterogeneous spectrum of clinical manifestations associated with immune dysregulation. In this study, we reported clinical, immunologic, and genetic evaluation two Iranian patients from unrelated families, both suffering recurrent respiratory tract infections, failure to thrive, interstitial lung disease, autoimmune cytopenia, hypogammaglobulinemia. Pulmonary abscess in one...
Mendelian susceptibility to mycobacterial disease (MSMD) is a rare group of genetic disorders characterized by infections with weakly virulent environmental mycobacteria (EM) or Mycobacterium bovis bacillus Calmette-Guérin (BCG). Herein, we described the case 4.5-year-old boy protein-losing enteropathy, lymphoproliferation, and candidiasis, who was found have disseminated simiae infection. A homozygous mutation in IL12B gene, c.527_528delCT (p.S176Cfs*12) identified, responsible for complete...
Disseminated Mycobacterium simiae infection in a patient with complete IL-12p40 deficiencySeyed Alireza Mahdaviani, MDa, Majid Marjani, MDb, Mahnaz Jamee, MDc,d*, Armin Khavandegar, MDc,d, Hosseinali Ghaffaripour, Golnaz Eslamian, MDe, Mehdi Ghaini, Shabnam Eskandarzadeh, Jean-Laurent Casanova, MD, PhDf,g,h,i, Jacinta Bustamante, PhDf,g,j, Davood Mansouri, MDa,b , Ali Akbar Velayati, MDa