A5002966185- Pneumonia and Respiratory Infections
- Immunodeficiency and Autoimmune Disorders
- Bacterial Infections and Vaccines
- Tuberculosis Research and Epidemiology
- Pediatric Urology and Nephrology Studies
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Brucella: diagnosis, epidemiology, treatment
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Pediatric health and respiratory diseases
- Antibiotic Resistance in Bacteria
- Respiratory viral infections research
- Hepatitis Viruses Studies and Epidemiology
- Vaccine Coverage and Hesitancy
- Urinary Tract Infections Management
- Immune responses and vaccinations
- SARS-CoV-2 and COVID-19 Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Kidney Stones and Urolithiasis Treatments
- Antibiotic Use and Resistance
- Bacterial biofilms and quorum sensing
- Clostridium difficile and Clostridium perfringens research
- COVID-19 Clinical Research Studies
- Congenital Anomalies and Fetal Surgery
Shahid Beheshti University of Medical Sciences
2015-2024
Shariati Hospital
2024
Bridge University
2024
Center for Children
2023
University of Mohaghegh Ardabili
2021
Kerman University of Medical Sciences
2021
Babol University of Medical Sciences
2020
Shahid Beheshti University
2013-2018
Tehran University of Medical Sciences
2011-2017
Indiana University – Purdue University Indianapolis
2013
There are many difficulties distinguishing bacterial from viral meningitis that could be reasonably solved using biomarkers. The aim of this study was to evaluate lactate, procalcitonin (PCT), ferritin, serum-CRP (C-reactive protein), and other known biomarkers in differentiating children.All children aged 28 days 14 years with suspected who were admitted Mofid Children's Hospital, Tehran, between October 2012 November 2013, enrolled prospective cross-sectional study. Children divided into 2...
Urinary tract infection is one of the most common diseases in children. Early diagnosis and com-prehensive treatment can significantly decrease late serious complications. Knowledge sensitivity resistance pattern uropathogens specific geographical locations an important factor for choosing suitable antibacterial treatment. This study was conducted order to evaluate urinary pathogens at Mofid Children's Hospital between March 2000 August 2001. Positive urine cultures from 1,177 children aged...
Background:: Metallo-beta-lactamase (MBL)-producing Acinetobacter baumannii is a growing therapeutic concern, worldwide. Objectives:: The aim of this study was to determine the frequency SPM and IMP type genes among A. isolates from hospitalized patients in Loghman Hakim Milad hospitals, Tehran-Iran 2012 2013. Patients Methods:: This conducted on 108 collected two hospitals Tehran, Iran. Antibiotic susceptibility tests were performed by Kirby-Bauer disc diffusion Broth microdilution methods...
To explore the serotype distribution and drug resistance patterns of invasive pneumococcal isolates from children under 5 years age.During a 32-month period, 585 clinical samples (including blood, cerebrospinal fluid (CSF), synovial fluid) suspected having meningitis, sepsis, pneumonia, or septic arthritis were analyzed using BACTEC culture system. Positive cultures examined biochemical tests lytA amplification for identification strains. The confirmed to determine capsular types modified...
Background . Acute gastroenteritis is one of the major sources morbidity and mortality among young children in developed developing countries. The aim this study was to determine prevalence human adenovirus- (HAdV-) 40 HAdV-41 hospitalized with five different health centers Iran. Methods In a cross-sectional epidemiological study, we studied 2682 fecal specimens that were collected from under age 5 years educational therapeutic pediatric Iran February 2012 2013. Samples tested for HAdV-40...
Loss of deoxyribonuclease I (Dnase1) function is associated with systemic lupus erythematosus (SLE) in humans and mice; however, no coding mutations Dnase1 are found polygenic murine models. Instead, both MRL-lpr strains NZB/W F1 hybrids homozygous for T89I missense the macrophage-DNASE, desoxyribonuclease I-like 3 (Dnase1l3). By vitro expression studies, this substitution decreases enzyme's nuclease activity against free DNA by only approximately twofold; mutation has a greater effect on...
Bordetella pertussis continues to circulate even in countries with good childhood vaccination coverage. This study was undertaken define the relationship between documented disease and clinical criteria proposed by World Health Organization (WHO).Nasopharyngeal swab samples were collected from previously healthy 6-14-year-old school children Tehran, presenting persistent cough of at least 2- week duration. Specimens examined for parapertussis culture polymerase chain reaction (PCR).Out 6601...
BackgroundDiphtheria (D), tetanus (T), pertussis (P), hepatitis B (HepB), invasive Haemophilus influenzae type b (Hib) disease, and measles cause substantial global morbidity mortality.MethodsThis unique review highlights geographic differences in disease burden across certain countries the African, Americas, Mediterranean, South-East Asian, Western Pacific World Health Organization (WHO) regions, relates this to vaccination coverage local vaccine recommendations using authors' as...
Monogenic immune dysregulation diseases (MIDD) are caused by defective immunotolerance. This study was designed to increase knowledge on the prevalence and spectrum of MIDDs, genetic patterns, outcomes in Middle East North Africa (MENA). MIDD patients from 11 MENA countries (Iran, Turkey, Kuwait, Oman, Algeria, Egypt, United Arab Emirates, Tunisia, Jordan, Qatar, Azerbaijan) were retrospectively evaluated. 343 (58% males 42% female) at a median (IQR) age 101 (42-192) months enrolled. The...
Brucellosis is being reported with increasing frequency in the Islamic Republic of Iran. Serum antibodies high-risk and general populations help to define cut-off levels can be used as a simple rapid diagnostic tests infected areas. We performed rose Bengal test (RBT), serum agglutination (SAT) 2-mercaptoethanol (2ME) titre determination on 415 healthy individuals including butchers, slaughterers others. Positive results were found by RBT, SAT (1:80) 2ME > or = 1:20 (10%, 20% 6%...
Background:: Serious infections by Pseudomonas aeruginosa are commonly treated with the combination of a beta-lactam antibacterial and an aminoglycoside. Therefore, production 16S rRNA methylase may result in extremely important resistance profile. Objectives:: The present study was conducted to determine prevalence Cephamycinase (CMY), aminoglycoside 6'-N-acetyltransferase (aac(6′)-Ib) genes among isolates from Iran. Patients Materials:: This descriptive performed on hospitalized burnt...
The rapid diagnosis of respiratory infections has always been an important goal for medical professionals, because and accurate leads to proper timely treatment, consequently, reduces the costs incorrect long-term treatments, antibiotic resistance. present study was conducted with aim detecting volatile organic compounds (VOCs) in three bacteria: Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae. Headspace studied bacteria, after separately culturing two types liquid...
Abstract Hepatocellular carcinoma (HCC) is one of the growing malignancies globally, affecting a myriad people and causing numerous cancer‐related deaths. Despite therapeutic improvements in treatment strategies over past decades, HCC still remains leading causes person‐years life lost. Numerous studies have been conducted to assess characteristics with aim predicting its prognosis responsiveness treatment. However, identified biomarkers shown limited sensitivity, translation these findings...
Analyzing the lineages and detecting antigenic variation in immunogenic motifs of Group A Rotavirus (RVA) variants is crucial because it can impact vaccine efficacy. This study investigated circulating VP4 VP7 proteins human RVA isolates their phylogeny ≤24-month-old symptomatic, rotavirus-positive children with transudative diarrhea within 48 h admission to Mofid Children's Hospital between December 2020 March 2022 Tehran, Iran. Antigen detection was performed by ELISA, RNA extraction,...