A5037080521- Asthma and respiratory diseases
- Immunodeficiency and Autoimmune Disorders
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Blood disorders and treatments
- Immune responses and vaccinations
- Date Palm Research Studies
- Tuberculosis Research and Epidemiology
- Eosinophilic Esophagitis
- Pediatric health and respiratory diseases
- Phytochemicals and Antioxidant Activities
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Autoimmune and Inflammatory Disorders Research
- Breastfeeding Practices and Influences
- T-cell and B-cell Immunology
- Inflammasome and immune disorders
- Essential Oils and Antimicrobial Activity
- Insect Pest Control Strategies
- Respiratory and Cough-Related Research
- Viral gastroenteritis research and epidemiology
- Mast cells and histamine
- Blood groups and transfusion
- Pneumocystis jirovecii pneumonia detection and treatment
- Infant Health and Development
- NF-κB Signaling Pathways
Mohammed Bin Rashid University of Medicine and Health Sciences
2021-2024
Children's Hospital
2024
Al Jalila Foundation
2022-2023
Tawam Hospital
2015-2023
United Arab Emirates University
2013-2022
Sana'a University
2018
Universitair Ziekenhuis Brussel
2014
Vrije Universiteit Brussel
2014
Pediatrics and Genetics
2009-2011
Background Prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10% reaches 20–30% those with an first-degree relative. Intestinal microbiota may modulate immunologic inflammatory systemic responses and, thus, influence development sensitization allergy. Probiotics been reported to immune their supplementation has proposed as a preventive intervention.Objective The World Allergy Organization (WAO) convened guideline panel develop...
The prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10 % reaches 20-30 those with an first-degree relative. Intestinal microbiota may modulate immunologic inflammatory systemic responses and, thus, influence development sensitization allergy. Prebiotics - non-digestible oligosaccharides that stimulate growth probiotic bacteria been reported to immune their supplementation has proposed as a preventive intervention.The World Allergy...
Background The prevalence of allergic diseases is approximately 10 % in infants whose parents and siblings do not have 20–30 those with an first-degree relative. Vitamin D involved the regulation immune system it may play a role development, severity course asthma other diseases.Objective World Allergy Organization (WAO) convened guideline panel to develop evidence-based recommendations addressing use vitamin primary prevention diseases.Methods Our WAO identified most relevant clinical...
Abstract Background No population study has explored the distribution of adult asthma in United Arab Emirates (UAE). The objective is to estimate prevalence general UAE. Methods Using standard European Community Respiratory Health Survey (ECRHS) questionnaires and tools, this a cross-sectional assessment random sample established quotas seven We surveyed 1,220 participants, which 63.2% were male, 20.1% UAE Nationals, with mean (SD) age 32.9 (14.1) years. Results Prevalence individual...
Clinical, genetic, and laboratory characteristics of Middle Eastern patients with multisystem inflammatory syndrome in children (MIS-C) have not yet been documented.To assess the genetic clinical MIS-C primarily Arab Asian origin.A prospective, multicenter cohort study was conducted from September 1, 2020, to August 31, 2021, United Emirates Jordan. Forty-five a matched control group 25 healthy confirmed SARS-CoV-2 infection status were recruited. Whole exome sequencing all 70 participants...
<i>Background and Purpose:</i> The primary cannabinoids, Δ<sup>9</sup>-tetrahydrocannabinol (Δ<sup>9</sup>-THC) Δ<sup>8</sup>-tetrahydrocannabinol (Δ<sup>8</sup>-THC) are known to disturb the mitochondrial function possess antitumor activities. These observations prompted us investigate their effects on O<sub>2</sub> consumption in human oral cancer cells (Tu183). This epithelial cell line overexpresses...
Monogenic immune dysregulation diseases (MIDD) are caused by defective immunotolerance. This study was designed to increase knowledge on the prevalence and spectrum of MIDDs, genetic patterns, outcomes in Middle East North Africa (MENA). MIDD patients from 11 MENA countries (Iran, Turkey, Kuwait, Oman, Algeria, Egypt, United Arab Emirates, Tunisia, Jordan, Qatar, Azerbaijan) were retrospectively evaluated. 343 (58% males 42% female) at a median (IQR) age 101 (42-192) months enrolled. The...
Abstract Background The CDC and ACIP recommend COVID-19 vaccination for patients with inborn errors of immunity (IEI). Not much is known about vaccine safety in IEI, whether attenuates infection severity IEI. Objective To estimate examine effect on outcomes Methods We built a secure registry database conjunction the US Immunodeficiency Network to frequency indicators effectiveness IEI patients. opened January 1, 2022, closed August 19, 2022. Results Physicians entered data 1245 from 24...
<i>Background:</i> Food allergy (FA) in children is an important health problem. However, the prevalence of FA United Arab Emirates (UAE) has not yet been determined. This cross-sectional study was carried out to assess among school aged 6–9 years Al-Ain city, UAE. <i>Methods:</i> We used multistage random sampling order get a sample 397 whose parents completed self-administered questionnaire designed presence or absence physician diagnosis and other allergic...
Allergic rhinitis is a morbid condition that frequently overlooked by patients and physicians. This type of atopy has not been adequately investigated in the United Arab Emirates.
A high prevalence of neutropenia has been reported in several ethnic groups amongst whom many healthy individuals with low neutrophil counts undergo unnecessary investigations. This study aims to ascertain the (NP) a large cohort children from North African, Middle Eastern, and Asian countries residing United Arab Emirates.Neutrophil 26,542 (one day six years age) 86 were analyzed. The subjects enrolled Well-Child-Care program Ambulatory Health Services Emirate Abu Dhabi, Emirates. NP was...
Chronic diseases (diabetes, cardiovascular and cancer), are by far the leading causes of mortality morbidity worldwide. Oxidative stress is one underlying mechanism in development enhancement chronic diseases. Polyphenols particularly abundant date seeds can contribute progress due to antioxidant properties. The present work studies effects examines oxidative status on serum organs Male Wistar rats after feeding them with basal diet comprising 0, 2, 4 or 8 g/kg seed powder (DSP) for a period...
A cross-over study was conducted in 16 healthy adult volunteers to describe the urinary excretion of polyphenols from date seeds and investigate antioxidant effect after consumption different doses powder (DSP), bread (DSB) extract (DSE). After 12 h fasting, one six treatments (0.25 g 0.5 g/kg bodyweight DSP, 360 10% 15% DSB, 30 mg 60 mg/kg DSE) provided along with breakfast, a two weeks wash-out period between 2 consecutive treatments. Blood drawn at baseline, 1, 2, 8 24 post intake. Urine...
Abstract Background Little is known about the etiology of childhood diarrhea in United Arab Emirates (UAE) especially after introduction rotavirus vaccines. This study aimed to identify gastrointestinal pathogens children with (cases) and carriage rate these asymptomatic (controls). Methods Stool samples were collected from 203 cases 73 controls who presented two major hospitals Al Ain city, UAE. Samples analyzed Allplex™ Gastrointestinal Full Panel Assay for common entero-pathogens. The...
We report on the pneumatocyte structure and function of mouse lung specimens exposed in vitro to two calcined mesoporous silica particles, MCM41-cal (spheres, ∼300 1000 nm diameter) SBA15-cal (irregular rods averaging ∼500 diameter ∼1000 length). These particles are consideration for potential medical application as delivery vehicles genes, drugs, bio-imagers. In study, (about 10 mg each) were excised from male Balb/c mice, immediately immersed Krebs-Henseleit buffer, ice-cold, continuously...
The Bacillus Calmette-Guérin (BCG) preparations are live-attenuated derivatives of Mycobacterium bovis. These products used to vaccinate infants at birth, a practice that may result in disseminated infection those patients who have an unidentified immunodeficiency.Patients were immunized birth with BCG and developed reported here emphasize the importance taking extensive medical history before giving vaccine. Patient 1 has sibling had familial hemophagocytic lymphohistiocytosis. 2 severe...
Purpose Inborn Errors of Immunity (IEI) are heterogeneous disorders immunity with variable clinical presentation and outcome. This is the first comprehensive report from United Arab Emirates aiming to describe demographics, characteristics, categories, treatment modalities outcome patients IEI. Methods retrospective study was conducted on who attended Tawam Hospital between 2016-2020. Results We identified 162 IEI, whom 152 were children. The age onset symptoms ranged birth 38 years. About...
Aflatoxin B1 (AFB1) is a naturally occurring carcinogenic and immunosuppressive compound. This study was designed to measure its toxic effects on human peripheral blood mononuclear cells (PBMC).
Primary immunodeficiency (PID) is a cluster of serious disorders that requires special alertness on the part medical staff for prompt diagnosis and management patient. This study explored PID knowledge experience among pediatricians wide educational backgrounds, practicing in United Arab Emirates (UAE). A self-administered questionnaire was used to determine competency their disorders. included questions signs symptoms, syndromes associated with immunodeficiency, screening tests,...