- Sleep and related disorders
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Circadian rhythm and melatonin
- Personality Disorders and Psychopathology
- Digital Mental Health Interventions
- Attention Deficit Hyperactivity Disorder
- Sleep and Wakefulness Research
- Tryptophan and brain disorders
- Child and Adolescent Psychosocial and Emotional Development
- Psoriasis: Treatment and Pathogenesis
- Psychological and Temporal Perspectives Research
- Perfectionism, Procrastination, Anxiety Studies
- Electroconvulsive Therapy Studies
- Mental Health and Psychiatry
- Autoimmune and Inflammatory Disorders Research
- Impact of Technology on Adolescents
- Psychological Well-being and Life Satisfaction
- Psychotherapy Techniques and Applications
- Spondyloarthritis Studies and Treatments
- Adolescent and Pediatric Healthcare
- Spaceflight effects on biology
- Youth Substance Use and School Attendance
- Blood Pressure and Hypertension Studies
- Sleep and Work-Related Fatigue
University of Oxford
2019-2025
Warneford Hospital
2020-2023
Oxford Centre for Computational Neuroscience
2023
Oxford Health NHS Foundation Trust
2021
National University of Ireland, Maynooth
2013-2020
Mood instability and circadian rhythm disruptions are both of increasing interest with regard to a number psychiatric disorders, notably bipolar disorder (BD), but understanding their nature interrelationship incomplete. By definition, have an integral temporal component and, as such, measuring them longitudinally remotely is desirable. We conducted the Cognition Evolution across Time (COMET) study assess feasibility value digital devices capture mood, its instability, daily rest-activity...
<sec> <title>UNSTRUCTURED</title> Borderline personality disorder (BPD) is a mental health condition with insufficient care availability worldwide. Digital interventions could reduce this treatment gap. Persuasive system design (PSD) conceptual framework outlining elements of digital that support behavior change. This systematic review aims to characterize targeting BPD symptoms, assess efficacy, and identify its association intervention features, including PSD elements. A automated symptoms...
Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioural which has been associated with sleep and circadian rhythm disturbances. Numerous studies have linked evening typology traits behaviours the disorder, although precise reason for this relationship not clarified. The current study examines ADHD symptoms, impulsivity, cognitive failures, quality chronotype in cohort of healthy young adults (N = 396). Results show significant, small magnitude associations between...
To differentiate the relation between structure and timing of rest-activity patterns symptoms impulsivity mood instability in bipolar disorder (BD), borderline personality (BPD) healthy controls (HC).Eighty-seven participants (31 BD, 21 BPD 35 HC) underwent actigraph monitoring for 28 days as part Automated Monitoring Symptom Severity (AMoSS) study. Impulsivity was assessed at study entry using BIS-11. Mood subsequently longitudinally monitored digital Zoom questionnaire.BPD show several...
Disruption of circadian rhythms is associated with several deleterious health consequences and cognitive impairment. It estimated that as many one in five workers are exposed to this risk factor due experiencing some degree chronodisruption by way recurring patterns shift work. not presently clear therefore how efficiently the mammalian system entrains alternative light/dark cycles such those found work schedules.The present study examines male CD-1 mice three different paradigms rapidly...
Abstract Sleep and circadian clock disruption are associated with neuropsychiatric disorders, such as attention deficit hyperactivity disorder, but the impact on neurocognitive performance is unclear. We assessed whether chronotype everyday misalignment manifested social jetlag were inter‐individual across domains of attention, inhibitory control decision making. One hundred eighty‐eight healthy young adults for sleep properties performed two tasks, Continuous Performance Test Iowa Gambling...
Background Perfectionism, low self-esteem and external locus of control are psychological constructs linked to insomnia, anxiety depression. Examining how these impact mental health serve as risk factors for the development clinically significant symptoms may help direct support resources preventative measures university students. Aims To longitudinally examine associations between aforementioned depression in a large representative sample first-year Method Electronic surveys including...
Abstract Bipolar disorder (BD) and borderline personality (BPD) are two psychiatric disorders with overlapping features that can be challenging to separate diagnostically. Growing evidence suggests circadian rhythm disturbances associated illness, however patterns of behaviour have not been elucidated in BPD or differentiated from BD. This study compared the structure timing rest-activity BD healthy volunteers. Participants ( N = 31) 21) controls (HC, 35) wore an actigraph on their...
Background: Psoriatic arthritis (PsA) is associated with sleep disturbance, depression and a lifetime risk of obesity cardiovascular disease. To date, there have been no studies investigating the relationship between objectively-measured physical activity (PA) levels circadian rhythm disturbance disease activity, daily symptoms mood in patients PsA. Objective: This pilot study aimed to investigate on PA Design: A prospective cohort recruiting adults PsA from rheumatology clinics at single...
Bipolar disorder (BD) is associated with excess and premature cardiovascular mortality. Elevated blood pressure (BP) a leading contributor to risk. However, few studies have examined BP in BD comparison other psychiatric disorders. Furthermore, the association between mood instability not presently clear despite increasing interest repurposing existing antihypertensive medications as possible novel treatments. Thus we differences borderline personality (BPD), similar symptom profile through...
People with personality disorder experience long waiting times for access to psychological treatments, resulting from a limited availability of long-term psychotherapies and paucity evidence-based brief interventions. Mentalisation-based treatment (MBT) is an efficacious therapeutic modality disorder, but little known about its viability as short-term treatment.
Background: Remote monitoring and digital phenotyping harbor potential to aid clinical diagnosis, predict episode course recognize early signs of mental health crises. Digital communication metrics, such as phone call short message service (SMS) use may represent novel biomarkers mood diagnosis in Bipolar Disorder (BD) Borderline Personality (BPD). Materials Methods: BD ( n = 17), BPD 17) Healthy Control (HC, 21) participants used a smartphone application which monitored calls SMS messaging,...