- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Suicide and Self-Harm Studies
- Digital Mental Health Interventions
- Electroconvulsive Therapy Studies
- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Heart Rate Variability and Autonomic Control
- Total Knee Arthroplasty Outcomes
- Coordination Chemistry and Organometallics
- Knee injuries and reconstruction techniques
- Tryptophan and brain disorders
- Advanced Neuroimaging Techniques and Applications
- Diabetes Management and Education
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neurotransmitter Receptor Influence on Behavior
- Child and Adolescent Psychosocial and Emotional Development
- Shoulder Injury and Treatment
- Spacecraft Design and Technology
- Ion channel regulation and function
- Spacecraft Dynamics and Control
University of Oxford
2016-2025
Yale University
2021-2022
University of Pittsburgh Medical Center
2021
Warneford Hospital
2016-2019
Oxford Health NHS Foundation Trust
2019
Sancheti Institute For Orthopaedics & Rehabilitation
2017
Mood instability and circadian rhythm disruptions are both of increasing interest with regard to a number psychiatric disorders, notably bipolar disorder (BD), but understanding their nature interrelationship incomplete. By definition, have an integral temporal component and, as such, measuring them longitudinally remotely is desirable. We conducted the Cognition Evolution across Time (COMET) study assess feasibility value digital devices capture mood, its instability, daily rest-activity...
Abstract Background Mobile technology enables high frequency mood monitoring and automated passive collection of data (e.g. actigraphy) from patients more efficiently less intrusively than has previously been possible. Such techniques are increasingly being deployed in research clinical settings however little is known about how such approaches experienced by patients. Here, we explored the experiences individuals with bipolar disorder engaging a study involving activity range portable...
Abstract Cognitive and neural mechanisms underlying bipolar disorder (BD) its treatment are still poorly understood. Here we examined the role of adaptations in risk-taking using a reward-guided decision-making task. We recruited volunteers with high ( n = 40) scores on Mood Disorder Questionnaire, MDQ, suspected risk for those low-risk 37). also patients diagnosed BD who were assigned (randomized, double-blind) to six weeks lithium 19) or placebo 16) after two-week baseline period 22 FMRI)....
Social rhythm irregularities are associated with increased bipolar disorder symptoms and suicide risk. This study was the first to examine feasibility acceptability of a 12-week social therapy (SRT) delivered predominantly via telehealth (three in-person sessions, nine video teleconferencing) adolescents young adults disorder. The primary aim determine SRT telehealth. Secondary aims were explore intervention's impacts on regularity, mood symptoms, propensity.Thirteen received modified called...
Purpose To study the additional effects of lumbar core stability on knee pain, range motion and function post ACL reconstruction. Methods An experimental comparative was undertaken at a tertiary orthopaedic rehabilitation centre with total 60 patients reconstruction, randomly allotted into two groups. Both groups were given institutional protocol; exercise programme to group. Intervention period 4 weeks. Pain VAS, (ROM) using Modified Lysholm Scoring Scale (MLSS) Tegner Activity Level (TAL)...
To reduce suicide in females with mood disorders, it is critical to understand brain substrates underlying their vulnerability future suicidal ideation and behaviors (SIBs) adolescence young adulthood. In an international collaboration, grey white matter structure was investigated adolescent adult (fSB) (fSI), without SIBs (fnonSIB).Structural (n = 91) diffusion-weighted 88) magnetic resonance imaging scans at baseline SIB measures follow-up on average two years later (standard deviation, SD...
Abstract Introduction Mood instability in bipolar disorder (BD) is poorly understood. Here we examined cognitive and neural mechanisms related to these fluctuations how they are changed with the mood stabilizer lithium. Methods We recruited volunteers low (n=37) or high (n=40) risk of BD (using Disorder Questionnaire, MDQ). also patients who were assigned (randomized, double-blind) six weeks lithium (n=19) placebo (n=16) after a two-week baseline period. Participants completed ratings daily...
A descriptive study was conducted to assess the effectiveness of Behavioral Change Communication on knowledge self care management diabetic foot ulcer among clients in Mappedu village.The objectives level Foot client pre test, To behavioral change communication post test and associate with demographic variable Totally 50 samples were selected using convenient sampling technique.The researcher developed a structured interview schedule variables .The is assessed questionarrie then after...