Aisling O’Driscoll

ORCID: 0000-0001-8197-0911
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About
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Research Areas
  • Vehicular Ad Hoc Networks (VANETs)
  • Mobile Ad Hoc Networks
  • Bacterial Identification and Susceptibility Testing
  • Genomics and Phylogenetic Studies
  • Opportunistic and Delay-Tolerant Networks
  • Advanced Wireless Network Optimization
  • Power Line Communications and Noise
  • Antimicrobial Resistance in Staphylococcus
  • Traffic control and management
  • Advanced MIMO Systems Optimization
  • Hemoglobinopathies and Related Disorders
  • Neonatal and Maternal Infections
  • Transportation and Mobility Innovations
  • Algorithms and Data Compression
  • Advanced biosensing and bioanalysis techniques
  • Age of Information Optimization
  • Gene expression and cancer classification
  • Peer-to-Peer Network Technologies
  • DNA and Biological Computing
  • Streptococcal Infections and Treatments
  • Multimedia Communication and Technology
  • Blood transfusion and management
  • Neutropenia and Cancer Infections
  • Embedded Systems Design Techniques
  • Cryptographic Implementations and Security

University College Cork
2016-2024

Munster Technological University
2007-2016

APC Microbiome Institute
2016

Worthing Hospital
2005-2007

St. James's Hospital
2005

University College Hospital
1994-1995

University College London
1994-1995

Rapid advancements in sequencing technologies along with falling costs present widespread opportunities for microbiome studies across a vast and diverse array of environments. These impressive technological developments have been accompanied by considerable growth the number methodological variables, including sampling, storage, DNA extraction, primer pairs, technology, chemistry version, read length, insert size, analysis pipelines, amongst others. This increase variability threatens to...

10.1371/journal.pone.0148028 article EN public-domain PLoS ONE 2016-02-05

Abstract We have identified a t(8;9)(p21-23;p23-24) in seven male patients (mean age 50, range 32-74) with diverse hematologic malignancies and clinical outcomes: atypical chronic myeloid leukemia/chronic eosinophilic leukemia (n = 5), secondary acute 1), pre-B-cell lymphoblastic 1). Initial fluorescence situ hybridization studies of one patient indicated that the nonreceptor tyrosine kinase Janus-activated 2 (JAK2) at 9p24 was disrupted. Rapid amplification cDNA ends-PCR 8p22 partner gene...

10.1158/0008-5472.can-04-4263 article EN Cancer Research 2005-04-01

Multiple sequence alignment (MSA) of DNA, RNA, and protein sequences is one the most essential techniques in fields molecular biology, computational bioinformatics. Next-generation sequencing technologies are changing biology landscape, flooding databases with massive amounts raw data. MSA ever-increasing data sets becoming a significant bottleneck. In order to realise promise for large-scale sets, it necessary existing algorithms be run parallelised fashion distributed over computing...

10.1155/2013/615630 article EN ISRN Biomathematics 2013-08-14

Abstract Technical Support call centres frequently receive several thousand customer queries on a daily basis. Traditionally, such organisations discard data related to enquiries within relatively short period of time due limited storage capacity. However, in recent years, the value retaining and analysing this information has become clear, enabling identify patterns, improve first resolution maximise closure rates. This paper proposes Proof Concept (PoC) end solution that utilises Hadoop...

10.1186/2196-1115-1-1 article EN cc-by Journal Of Big Data 2014-06-24

This paper provides an in-depth review and discussion of the state art in redundancy mitigation for vehicular Collective Perception Service (CPS). We focus on evolutionary differences between rules proposed 2019 ETSI TR 103 562 versus 2023 technical specification TS 324, which uses a Value Information (VoI) based approach. also critically analyse academic literature that has sought to quantify communication challenges posed by CPS present unique taxonomy approaches using three distinct...

10.48550/arxiv.2501.01200 preprint EN arXiv (Cornell University) 2025-01-02

Summary. Plasma NOx concentrations were raised in 22 acute painful crises SCD. We have measured blood of nitric oxide metabolites (NOx) sickle‐cell disease (SCD), and shown that they are increased compared with healthy controls (P = 0.002), haemoglobin E/β‐thalassaemic (P=0.05). Concentrations steady‐state SCD also higher than 0.04) but not significantly different from the at beginning 0.34). Importantly, 12 regularly exchanged sicklers, mean pre‐transfusion concentration did differ control...

10.1111/j.1365-2141.1995.tb05397.x article EN British Journal of Haematology 1995-12-01

In this work the authors present first publicly available, open-source simulation model of Third Generation Partnership Project (3GPP) Release 14 Cellular Vehicle to Everything (C-V2X) standard. The specifically addresses Mode 4, in which vehicles communicate directly peer mode using a distributed resource allocation algorithm. Importantly, is fully compliant with existing service and application layers already defined by automotive standards communities, providing standardised cross-layer...

10.1109/camad.2019.8858436 article EN 2019-09-01

This paper presents OpenCV2X, the first publicly available, open-source simulation model of Third Generation Partnership Project (3GPP) Release 14 Cellular Vehicle to Everything (C-V2X) sidelink, which forms basis for 5G NR Mode 2 under later releases. is fully compliant with existing vehicular service and application layers, including messaging sets as defined by automotive standards communities providing a standardised, cross-layer communication model. Using this model, we show how current...

10.48550/arxiv.2103.13212 preprint EN cc-by arXiv (Cornell University) 2021-01-01

Low plasma heparin cofactor II (HCII) levels are associated with a thrombotic tendency, and we have previously shown these to be decreased in variety of haemolytic conditions. The risk thrombosis is recognized increased both thalassaemia major (TM) intermedia (TI), although the exact mechanisms poorly understood. HCII therefore been compared 20 untrans‐fused patients TI regularly transfused TM determine influence transfusion on HCII. Additionally, untransfused commenced regular red cell...

10.1111/j.1365-2141.1995.tb03381.x article EN British Journal of Haematology 1995-05-01

With world wide data predicted to exceed 40 trillion gigabytes by 2020, big storage is a very real and escalating problem. Herein, we discuss the utility of synthetic DNA as robust eco-friendly archival solution future.

10.4161/bioe.24296 article EN Bioengineered 2013-03-20

This paper presents an Infrastructure Enhanced Geographic Routing Protocol (IEGRP) for urban vehicular environments. IEGRP is a hybrid routing protocol that facilitates V2V or V2I unicast by dynamically changing its decisions in the presence of full partial Road-Side Unit (RSU) infrastructure order to maximise packet delivery rate. To best author's knowledge this first approach where algorithm exploits available but also utilises efficient multi-hop communications using greedy forwarding,...

10.1109/wivec.2013.6698227 article EN 2013-06-01

Summary Hepatic venocclusive disease causes considerable morbidity and mortality following bone marrow transplantation. There are two hypotheses regarding the aetiology of this syndrome; firstly that changes in plasma coagulation factors natural anticoagulants lead to a prothrombotic state secondly endothelial cell activation stimulates intravascular deposition fibrin. We have investigated these mechanisms by measuring proteins C S VII X post transplant period using concentration factor Vila...

10.1055/s-0038-1648806 article EN Thrombosis and Haemostasis 1994-01-01

This paper presents a detailed quantitative evaluation of standardised Decentralised Congestion Control (DCC) and packet dropping mechanisms for Cellular V2X (C-V2X). Based on the identified shortcomings, an Access layer DCC scheme, RRI adaptive, is then proposed. adaptive accommodates sidelink scheduling mechanism Sensing Semi-Persistent Scheduling (SB-SPS), eliminating incompatibilities between current standards mechanism, to avoid unnecessary reoccurring collisions. Two variants are...

10.48550/arxiv.2106.04871 preprint EN cc-by arXiv (Cornell University) 2021-01-01

Both Peer-to-Peer (P2P) and Mobile Ad-hoc Networks (MANETs) aim to provide seamless connectivity services in a dynamic decentralised environment. These two technologies, if unified, may be able realise MANETs as viable commercial technology will enable the development of widespread distributed applications for MANETs. The push towards wireless ubiquitous computing means that service providers need adapt highly mobile topology given client-server can not supported such an environment, P2P...

10.1109/icmwcn.2007.4668184 article EN 2007-09-01

It is expected that future vehicular networks will consist of a combination ad-hoc network and infrastructure components. Road Side Units (RSUs) form part the element. However, it anticipated fully deployed RSU may not be economically feasible in short term, therefore, partial urban environments more likely, at least initially while are being adopted. further likely low vehicle penetration rates exist 802.11p On-Board Unit (OBU) technology rolled out, thus routing schemes should exploit...

10.1109/vnc.2013.6737591 article EN 2013-12-01

Adaptation of the Modulation and Coding Scheme (MCS) within Cellular Vehicle-To-Everything (C-V2X) sidelink has potential for a wide range applications including congestion control, support variable packet sizes, density aware rate adaptation improved unicast transmissions. However, practical implementation MCS presents implications C-V2X radio resources, bandwidth, computation power levels operation scheduling mechanism. This paper first study that provides detailed analysis an implemented...

10.1109/cscn53733.2021.9686168 preprint EN 2021-12-15

Network simulations are often the first choice to design, test, and evaluate novel applications protocols for vehicular networks. Aiming higher realism, simulators become increasingly complex, relying on detailed simulation models that developed by different communities. With this trend, it also becomes difficult understand all in detail researchers might lack expert knowledge parameterize such properly. In paper, we identify suboptimal default parameter values physical layer effects common...

10.1109/wd.2019.8734227 article EN 2019-04-01

Herein, we report the draft genome sequence of Streptococcus agalactiae ED-NGS-1000, cultivated from a blood sample taken preterm neonate sepsis patient at Royal Infirmary, Edinburgh, Scotland, United Kingdom.

10.1128/genomea.00875-14 article EN Genome Announcements 2014-09-05

A 33-year-old woman was receiving her second cycle of combination chemotherapy (etoposide, methylprednisolone, cytarabine, cisplatin; ESHAP) for relapsed Hodgkin lymphoma when she complained worsening dyspnoea. Until this point had been well, disease having detected on a follow-up computerised tomography (CT) scan. The patient not received radiotherapy as part initial treatment. At presentation tachycardic (110 bpm) and hypotensive (blood pressure 90/55 mm Hg). jugular venous elevated at 10...

10.1111/j.1365-2141.2007.06589.x article EN British Journal of Haematology 2007-04-19

This paper presents a detailed quantitative evaluation of standardised ETSI & 3GPP Decentralised Congestion Control (DCC) and packet dropping mechanisms for Cellular V2X (C-V2X) New Radio (NR) V2X. Based on the identified shortcomings, an Access layer scheme, RRI DCC, is then proposed. DCC explicitly accommodates sidelink scheduling mechanism Sensing Semi-Persistent Scheduling (SB-SPS), eliminating incompatibilities between current standards mechanism, to avoid unnecessary recurring...

10.1109/wowmom54355.2022.00045 article EN 2022-06-01

The application of ex vivo synthetic DNA as a high capacity information storage medium is well documented. Herein, we consider the potential for to be incorporated part human genome; providing definitive, accessible, in database patient history.

10.4161/adna.25489 article EN Artificial DNA PNA & XNA 2013-04-01
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