A5049306237- Flexible and Reconfigurable Manufacturing Systems
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Neurobiology and Insect Physiology Research
- Energy Efficiency and Management
- Digital Transformation in Industry
- Child and Adolescent Psychosocial and Emotional Development
- Physics and Engineering Research Articles
- Olfactory and Sensory Function Studies
- Advanced Manufacturing and Logistics Optimization
- Scheduling and Optimization Algorithms
- Insect and Arachnid Ecology and Behavior
- Primate Behavior and Ecology
- Anesthesia and Neurotoxicity Research
- Regulation of Appetite and Obesity
- Neuroscience of respiration and sleep
- Animal Behavior and Reproduction
- Anesthesia and Sedative Agents
- Insect Pheromone Research and Control
- Genetics, Aging, and Longevity in Model Organisms
- Industrial Vision Systems and Defect Detection
- Congenital heart defects research
- Real-Time Systems Scheduling
- Neuroscience and Neuropharmacology Research
- Safety Systems Engineering in Autonomy
The Francis Crick Institute
2019-2024
Howard Hughes Medical Institute
2016-2021
Harvard University
2015-2021
MRC Laboratory of Molecular Biology
2011-2019
Institut für Holztechnologie Dresden
2019
Friedrich-Alexander-Universität Erlangen-Nürnberg
2014-2016
Institute of Automation
2014-2016
Sainsbury Wellcome Centre
2016
Medical Research Council
2014
Georg Simon Ohm University of Applied Sciences Nuremberg
2013
During pregnancy, physiological adaptations prepare the female body for challenges of motherhood. Becoming a parent also requires behavioral adaptations. Such can occur as early during but how pregnancy hormones remodel parenting circuits to instruct preparatory changes remains unknown. We found that action estradiol and progesterone on galanin (Gal)–expressing neurons in mouse medial preoptic area (MPOA) is critical pregnancy-induced parental behavior. Whereas silences MPOA Gal...
The Drosophila sex pheromone cVA elicits different behaviors in males and females. First- second-order olfactory neurons show identical responses, suggesting that genes differentially wire circuits deeper the brain. Using vivo whole-cell electrophysiology, we now two clusters of third-order have dimorphic responses. One cluster responds females; other males. These are present both sexes share a common input pathway, but sex-specific wiring reroutes information. Regulating dendritic position,...
Most sensory systems are organized into parallel neuronal pathways that process distinct aspects of incoming stimuli. In the insect olfactory system, second order projection neurons target both mushroom body, required for learning, and lateral horn (LH), proposed to mediate innate behavior. Mushroom body form a sparse population code, which is not stereotyped across animals. contrast, odor coding in LH remains poorly understood. We combine genetic driver lines, anatomical functional criteria...
Significance Cellular and subcellular structures in thick biological samples typically are visualized either by genetically encoded fluorescent proteins or antibody staining against of interest. However, both approaches have drawbacks. Fluorescent do not survive treatments for tissue preservation well, available only a few colors, often emit weak signals. Antibody stainings slow, penetrate result considerable background staining. We overcome these limitations using chemical tags that rapid,...
This paper presents an experimental study to validate a dynamic model of six-axis industrial robot as part assembly system and analyze its power consumption well behavior. Furthermore, the effect operating parameters (i.e., payload speed) on behavior are analyzed. The investigation shows that comparative between simulation results can be used improve model's accuracy prove represents real system. Both show strongly influence robot's
While recent studies have uncovered dedicated neural pathways mediating the positive control of parenting, regulation infant-directed aggression and how it relates to adult-adult is poorly understood. Here we show that
Load management systems are increasingly being used in companies to reduce the energy costs of production. However, success a load system depends on quality consumption estimation. The present approach illustrates potential predict individual products and their variants without need for setting up new data model. For this purpose, methodology is developed upgrading any existing material flow model with energetic aspects. aim related work generation non- redundant low modeling efforts user.
The increasing complexity of production plants in the context Industry 4.0 poses new challenges with regards to technical maintenance and process control. In this context, Cyber-Physical Systems (CPS) for intelligent condition monitoring enable fault-tolerant, predictable systems. Unfortunately, CPS Condition Monitoring System development is challenging due distribution computational tasks among heterogeneous industrial IT-architectures. It usually started from scratch, which time-consuming...
Cyber-Physical Production Systems (CPPS) help to cope with complexity and offer the computing platforms for sophisticated data analytics in smart factories. Nevertheless, operation of CPPS, integration tacit knowledge human as a maintainer has not been considered yet improvement monitoring diagnosis processes production systems. The basic motivation this publication is development framework technical maintenance systems context cyber-physical environment, which conforms reference...
In industrial manufacturing, high system availability is the most effective lever for increasing productivity. For minimal downtimes, it important to identify sources of errors at an early stage in order perform scheduled maintenance. Especially field electric drives thermo-crimping process one major technology join insulated copper wires with belonging current carrying parts. However, due its operating principle, this has be associated strong disadvantages. Primarily, excessive tool...
Industrial production systems meet strict requirements regarding availability, process control and condition monitoring. As a key enabler of Industry 4.0, cyber-physical form the core modular, web-based framework, which delivers more efficient monitoring mechanisms for maintenance staff in facilities. The present approach illustrates potential decentralized centralized, distributed system by using standardized communication protocols semantic information models. use platforms like node.js...
The establishment of green products and a sustainable production increasingly affects corporate competitiveness, as an efficient does not only affect the energy costs, but also improves company image. As importance renewable sources increases, mainly providing unsteady levels, load management manufacturing assembly lines fades into spotlight. For this purpose, proper measuring equipment is required, being able to log evaluate varying loads.This paper entails approach automatically measure...
Abstract The energy turnaround in Germany increases the share of renewable energies. Since amount supply is immanently subject variation, electricity price at European Energy Exchange EEX highly volatile. If companies would purchase directly instead from a wholesale power supplier along with fixing, benefit increasing production times low costs and reducing high-cost times. This paper shows, that influencing respectively shifting time consumption –e.g. by adjustment process parameter, shift...
ABSTRACT While recent studies have uncovered dedicated neural pathways mediating the positive control of parenting, regulation infant-directed aggression and how it relates to adult-adult is poorly understood. Here we show that urocortin-3 ( Ucn3 )-expressing neurons in hypothalamic perifornical area (PeFA ) are activated during attacks males females, but not other behaviors. Functional manipulations PeFA demonstrate role this population negative parenting both sexes. receive input from...
Kurzfassung Angesichts des zunehmenden gesellschaftlichen Bewusstseins für Belange der CSR (Corporate Social Responsibility) wird Produktionsfaktor Energie nicht nur kostspieliger, sondern beeinflusst ebenso das Image Unternehmens. Um die resultierenden Forderungen an Produktion realisieren zu können, bieten sich Simulationen an, da sie ohne Unterbrechung virtuell Energieverbräuche aufdecken.