A5100773742- Tracheal and airway disorders
- Airway Management and Intubation Techniques
- Diabetes Management and Research
- Essential Oils and Antimicrobial Activity
- Drug Transport and Resistance Mechanisms
- Autophagy in Disease and Therapy
- Lung Cancer Diagnosis and Treatment
- Pancreatic function and diabetes
- Sirtuins and Resveratrol in Medicine
- Cholesterol and Lipid Metabolism
- Vascular Anomalies and Treatments
- Pleural and Pulmonary Diseases
- Computational Drug Discovery Methods
- Pneumothorax, Barotrauma, Emphysema
- Cancer, Lipids, and Metabolism
- Diabetes Treatment and Management
- Thyroid and Parathyroid Surgery
- Histone Deacetylase Inhibitors Research
- Cancer, Hypoxia, and Metabolism
- Trauma Management and Diagnosis
- Diabetes and associated disorders
- Dysphagia Assessment and Management
- Medical Imaging and Pathology Studies
- Machine Learning in Bioinformatics
- Biomarkers in Disease Mechanisms
Ain Shams University
2014-2025
University of Liège
2024
Max Delbrück Center
2024
Trinity Health
2024
Nazareth Hospital
2024
Helwan University
2023
National Water Research Center
2023
Mansoura University
2022
Ain Shams University Hospital
2021
University of Michigan
2020
Oxidative stress is usually associated with many neurodegenerative diseases. In this study, the gas chromatography–mass spectrometry (GC–MS) analysis of cold-pressed oil (CPO) from black pepper (Piper nigrum) fruits was performed and its neuroprotective effects were evaluated for first time. The CPO revealed presence lignan sesamin (39.78%), alkaloid piperine (33.79%), monoterpene hydrocarbons 3-carene (9.53%) limonene (6.23%), sesquiterpene β-caryophyllene (10.67%). Black hydrodistilled...
Cutaneous melanoma remains the most lethal skin cancer, and ranks third among all malignancies in terms of years life lost. Despite advent immune checkpoint targeted therapies, only roughly half patients with advanced achieve a durable remission. Sirtuin 5 (SIRT5) is member sirtuin family protein deacylases that regulates metabolism other biological processes. Germline Sirt5 deficiency associated mild phenotypes mice. Here we showed SIRT5 was required for proliferation survival across...
This study explores the metabolic profile and wound-healing capabilities of Ficus trijuja, a species within Moraceae family, for first time. plants contain variety secondary metabolites such as flavonoids, triterpenoids, alkaloids, known their antioxidant, anti-inflammatory, cytotoxic properties. Previous studies demonstrated effectiveness extracts in wound healing, with evidence improved contraction, strength, faster epithelization. shows impact F. trijuja extract gel base well when...
The purpose of this work is to review the state art telemedicine within context physiotherapy, guided by an interest in uncovering advantages, drawbacks, and further prospects for use. This research sought evaluate impact on physiotherapy services focusing distance care delivery determine difficulties observed utilizing healthcare professions patients physiotherapy. study also explored role technology training enhancement based future enhance patient care. Some conclusions that were made...
Efficient control of automotive engine idle speed is crucial for achieving better fuel economy and smoother running. This paper presents a comparison between proportional-integral-derivative (PID) Reinforcement Learning (RL) using the Deep Q-Network (DQN) algorithm as high-level method minimizing fluctuations caused by changes in irregularities, response time accuracy throttle mechanism. In addition to low-level PID valve position, MATLAB/Simulink was employed build simulation environment,...
The incidence of retrosternal goiter (RSG) varies from 2% to 26% all thyroidectomies, depending on the defining criteria. There are no clear guidelines identify patients that require an intrathoracic approach. So, we tried correlate, between size and/or anatomical site RSG based preoperative CT findings and surgical approaches used, aiming at those with who in need for thoracic approach.Out 1481 underwent thyroidectomy National Cancer Institute (NCI), Cairo University, January 2000 December...
EALTHCARE textiles are a major segment of medical because they one the markets for technical that growing fastest.To provide an antibacterial, blood-and water-repellent finish, numerous classes compounds have been created.. Our aim here is to treat pure cotton and polyester/cotton blended fabrics with perfluoro-heptyl-methacrylate (PFHMA) as well magnesium oxide nanoparticles (MgONPs) impart multifunctional properties fabrics.The treated substrates tested by measuring contact angle,...
Abstract Many reports suggested that some statins are almost ineffective in reducing triglycerides or enhancing HDL‐C plasma levels, although statin treatment was still efficacious LDL‐C. In diabetic dyslipidemic patients, it may therefore be necessary to use a combination therapy with other drugs achieve either LDL‐C‐ and triglyceride‐lowering HDL‐C‐enhancing goals. Such ineffectiveness of can attributed their effect on the liver X receptor (LXR) which regulates expression ATP‐binding...
Coronaviruses caused an outbreak pandemic disease characterized by a severe acute respiratory distress syndrome leading to the infection of more than 200 million patients and death 4 individuals. The primary treatment is either supportive or symptomatic. Natural products have important role in development various drugs. Thus, screening natural compounds with reported antiviral activities can lead discovery potential inhibitory entities against coronaviruses. In current study, in-silico...
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes chronic injury and strongly associated with type 2 diabetes mellitus (T2DM). Pentraxin 3 (PTX3) an acute‑phase reactant essential component innate immunity. Plasma PTX3 level is, according to some data, a marker for NAFLD. We aimed assess value serum as non-invasive bio-marker NAFLD in patients Type II DM. Methods This case-control study included 96 subjects classified 32 T2DM NAFLD, without healthy...
Cestrum diurnum L. (Solanaceae) is a fragrant ornamental tree cultivated in different parts around the world. In this study, essential oil (EO) of aerial was extracted by hydrodistillation (HD), steam distillation (SD) and microwave-assisted hydro-distillation (MAHD). GC/MS analysis three EOs revealed that phytol represents major component SD-EO MAHD-EO (40.84 40.04 %, respectively); while HD-EO it only represented 15.36 %. The showed strong antiviral activity against HCoV-229E with IC50...
The conventional methods used for the diagnostics of viral infection are either expensive and time-consuming or not accurate enough dependent on consumable reagents. In presence pandemics, a fast reagent-free solution is needed mass screening. Recently, diagnosis infections using infrared spectroscopy has been reported as low-cost method. this work corona detection based compact micro-electro-mechanical systems (MEMS) device artificial intelligence (AI) suitable deployment presented. Among...
Innominate artery cannulation for conducting cardiopulmonary bypass has been proposed as an alternative site in surgeries involving proximal thoracic aorta. Evaluate a safe reliable route during Thoracic Aortic surgery. Between January 2010 and October 2016, 30 adult patients had the aorta single center. Operations performed were 26 (86.7%) Ascending replacements of which 6 (23%) concomitant valve replacement 5 (19.2%) coronary grafts, 3 (10%) Modified Bentall's procedure one patient (3.3%)...
We report the case of a 38-year-old Middle Eastern man with intractable right upper quadrant (RUQ) abdominal pain and several emergency department visits during last seven years, extensive repeated radiologic endoscopic workups proven negative for biliary or gastrointestinal disease. He presented to our outpatient surgical clinic in March 2023 complaining worsening RUQ epigastric was scheduled robotic cholecystectomy presumed dyskinesia following repeat cholescintigraphy (hepatobiliary...
Tyrosylprotein sulfotransferases (TPST1 and TPST2) are only known to exist in the Golgi. Thus, Yu et al.'s findings (Nat. Chem. Biol. 2023; https://doi.org/10.1038/s41589-023-01267-9) that histone H3 sulfation occurs cytosol surprising. Cytosolic sulfotransferase SULT1B1, which sulfates phenolic small molecules, was proposed catalyze H3Y99 with 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as SO3 donor. Bottom-up liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomic...
The pancreas plays a key role in the endocrine system of animals and digestion absorption nutrients. exocrine are structurally separate from each other, but numerous studies suggest anatomical functional connections between these parts. Previously, less attention was paid to interactions, is now viewed as single organ consisting functionally related components that coordinates responses. Our review examines latest data indicating connection mutual influence parts pancreas. In addition, we...