A5052808255- Epigenetics and DNA Methylation
- Birth, Development, and Health
- Health, Environment, Cognitive Aging
- Neonatal Respiratory Health Research
- Gestational Diabetes Research and Management
- Prenatal Screening and Diagnostics
- Breastfeeding Practices and Influences
- Health disparities and outcomes
- Mobile Health and mHealth Applications
- Gut microbiota and health
- Infant Health and Development
- Health Literacy and Information Accessibility
- Diet and metabolism studies
- Sport Psychology and Performance
- Obesity, Physical Activity, Diet
- Trauma and Emergency Care Studies
- Nutritional Studies and Diet
- Hip and Femur Fractures
- COVID-19 and healthcare impacts
- Sports injuries and prevention
- Data-Driven Disease Surveillance
- ICT in Developing Communities
- Food Security and Health in Diverse Populations
McMaster University
2016-2024
Logan Hospital
2021
Queensland Health
2021
Metro South Health
2021
Management Sciences for Health
2014
The infant gut is rapidly colonized by microorganisms soon after birth, and the composition of microbiota dynamic in first year life. Although a stable microbiome may not be established until 1 to 3 years appears an important predictor health outcomes later We obtained stool at one age from 173 white Caucasian 182 South Asian infants two Canadian birth cohorts gain insight into how maternal early infancy exposures influence development microbiota. investigated whether differed ethnicity...
In Malawi, where the majority of population resides in rural areas, community health workers (CHWs) are first, and often only, providers services. An assessment information needs, however, found that these frontline lacked essential information. A pilot project, implemented 2 districts Malawi between 2010 2011, introduced a mobile phone system to strengthen knowledge exchange within networks CHWs district staff. To evaluate intervention, participatory evaluation method called Net-Map was...
Maternal smoking has been linked to adverse health outcomes in newborns but the extent which it impacts newborn not quantified through an aggregated cord blood DNA methylation (DNAm) score. Here, we examine feasibility of using DNAm scores leveraging large external studies as discovery samples capture epigenetic signature maternal and its influence on White European South Asian populations. We first examined association between individual CpGs cigarette during pregnancy, exposure two birth...
Epigenetic modifications, particularly DNA methylation (DNAm) in cord blood, are an important biological marker of how external exposures during gestation can influence the in-utero environment and subsequent offspring development. Despite recognized importance DNAm gestation, comparative studies to determine consistency these epigenetic signals across different ethnic groups largely absent. To address this gap, we first performed epigenome-wide association (EWAS) gestational age (GA) using...
Maternal smoking has been linked to adverse health outcomes in newborns but the extent which it impacts newborn not quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine feasibility of using DNAm scores leveraging large external studies as discovery samples capture epigenetic signature maternal and its influence on White European South Asian populations. We first examined association between individual CpGs cigarette during pregnancy, exposure two birth...
Maternal smoking has been linked to adverse health outcomes in newborns but the extent which it impacts newborn not quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we propose first DNAm score capture epigenetic signature of maternal smoking. We examined association between individual CpGs and cigarette during pregnancy two White European birth cohorts (n = 763), exposure South Asian 887). Several previously reported genes for were supported, with strongest most...
Abstract Background Epigenetic modifications, particularly DNA methylation (DNAm) in cord blood, are an important biological marker of how external exposures during gestation can influence the in-utero environment and subsequent offspring development. Despite recognized importance DNAm gestation, comparative studies to determine consistency these epigenetic signals across different ethnic groups largely absent. To address this gap, we first performed epigenome-wide association (EWAS)...
Maternal smoking has been linked to adverse health outcomes in newborns but the extent which it impacts newborn not quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine feasibility of using DNAm scores leveraging large external studies as discovery samples capture epigenetic signature maternal and its influence on White European South Asian populations. We first examined association between individual CpGs cigarette during pregnancy, exposure two birth...
Abstract Maternal smoking has been linked to adverse health outcomes in newborns but the extent which it impacts newborn not quantified through an aggregated cord blood DNA methylation (DNAm) score. Here we examine feasibility of using DNAm scores leveraging large external studies as discovery samples capture epigenetic signature maternal and its influence on White European South Asian populations. We first examined association between individual CpGs cigarette during pregnancy, exposure two...
Background: The traditional model of care the Orthopaedic Fracture Clinic (OFC) is labour intensive, expensive, has poor satisfaction rates, and often minimal impact on management outcomes patients with minor injuries. Our aim was to implement a Virtual (VFC) for injuries that safe, reduces OFC clinic workload failure attend (FTA) rate. Methods: This study retrospective longitudinal audit before (January 2012 -February 2017) after (March 2017 – December 2019) implementation VFC. It performed...
Abstract Background COVID research and reporting has focused on large urban populations. However, limited data suggests that rural Native American (NA) populations are disparately impacted. We serve a well-defined NA population of ≈18,000 is relatively geographically isolated in the White Mountains eastern Arizona. Our first case SARS-CoV-2 was confirmed April 1st. have since an attack rate significantly higher than most United States. provide testing trends addition to characteristics 800...