A5024385574- Muscle and Compartmental Disorders
- Dialysis and Renal Disease Management
- Cardiac electrophysiology and arrhythmias
- Acute Kidney Injury Research
- Vasculitis and related conditions
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Multiple Myeloma Research and Treatments
- Electrolyte and hormonal disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Chronic Kidney Disease and Diabetes
- Pharmacological Effects and Toxicity Studies
- Urticaria and Related Conditions
- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- Eosinophilic Disorders and Syndromes
- Neurological and metabolic disorders
- Renal Diseases and Glomerulopathies
- Quantum Electrodynamics and Casimir Effect
- Cardiac Arrhythmias and Treatments
- Chronic Lymphocytic Leukemia Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Bone and Joint Diseases
- Bone health and treatments
- Acute Ischemic Stroke Management
Ospedale Bassini
2020-2025
Milano Metropoli Development Agency
2020-2025
Aziende Socio Sanitarie Territoriale Nord Milano
2020-2025
University of Milano-Bicocca
2003-2024
Azienda Ospedaliera San Gerardo
2010-2016
University of Milan
2012-2013
St. Paul's Hospital
2012
Amsterdam UMC Location Vrije Universiteit Amsterdam
2006-2010
University Medical Center
2010
University Hospital and Clinics
2010
A high prevalence of prolonged QT interval duration has been observed among haemodialysis (HD) patients. The aim this cases series was to describe the association various risk factors with total mortality and sudden cardiac death (SCD) in population.One hundred twenty-two patients undergoing HD, [median: age 71.3 years [interquartile ratio (IQR) 62.9-76.6], HD 3.0 (IQR 1.3-7.8) 64.8% male], which 37.7% ischaemic disease, 41.8% dilated cardiomyopathy (DC), 84.4% hypertension, 27.1% diabetes,...
Daily peritoneal exposure to dialysis fluid (PDF) induces severe morphological alterations including fibrosis and angiogenesis that lead a loss of ultrafiltration (UF) capacity. Since cyclooxygenase (COX)-2 is involved in angiogenesis, we investigated the vivo effects selective COX-2 inhibitor (celecoxib) rat-PD model.Sixteen rats daily received 10 ml conventional PDF for 4-5 weeks intraperitoneally. Half them (n = 8) celecoxib (20 mg/kg BW) via oral gavage, other half vehicle gavage. The...
Abstract Data on the effectiveness of denosumab osteoporosis after kidney transplantation are limited. We investigated long-term bone mineral density (BMD) changes in transplant recipients (KTRs) treated with compared to untreated KTRs. enrolled KTRs 60 mg/6 months for 4 years. An group sex and age-matched a 1:1 ratio was included. The primary outcome BMD assessed by Dual-energy X-ray Absorptiometry over serum creatinine, alkaline phosphatase (ALP), parathyroid hormone, 25-hydroxyvitamin D...
Acute kidney injury (AKI) during hospitalization is associated with increased complications and mortality. Despite efforts to standardize AKI management, its recognition in clinical practice limited.
To analyse the duration of QT interval and its relationship with heart rate changes in patients uraemia, before during haemodialysis.QT RR intervals were measured automatically using a dedicated algorithm 24-h Holter recordings 29 (15 women) receiving chronic haemodialysis. corrected for (QTc) slope QT/RR linear regression calculated. Arterial blood pressure (ABP) was Plasma concentrations K+, Mg2+ Ca2+ assessed after haemodialysis.ABP decreased significantly from baseline (102.7 +/- 11.0...
AimsHaemodialysis (HD) therapy represents a unique model to test in vivo, humans, the effects of changes plasma ionic concentrations. Episodes paroxysmal atrial fibrillation (AF) often occur during treatment. We investigated HD-induced electrolyte variations on electrophysiology by analysing ECG P-wave duration (PWd), which reflects conduction velocity (CV), and simulated action potential (AP).
Polymethylmethacrylate (PMMA) membranes can adsorb a wide variety of uremic toxins including serum free light chains (sFLC). However, limited data are available regarding the clinical use PMMA in multiple myeloma patients and its maximum adsorption capacity this setting.This study aimed to measure sFLC identify strategies improve efficiency practice.Ten with dialysis-dependent renal failure high levels were included study. Five received standard hemodialysis (HD; n = 18), while other 5 new...
Because of its dynamic structure, the omentum plays a key role in immunity peritoneal cavity by orchestrating cell recruitment. mast cells accumulate upon experimental dialysis (PD) and may produce angiogenic/profibrotic factors, it was hypothesized that mediate omental tissue remodeling during PD. Daily treatment with conventional PD fluid (PDF) for 5 wk resulted strong response, characterized an approximately 10-fold increase density (P < 0.01), 20-fold vessel 0.02), number milky spots...
The aim of our study was to evaluate whether convective (haemofiltration, Hf) and diffusive (haemodialysis, Hd) dialysis techniques induce different patterns long- short-term autonomic adjustments in haemodynamically stable patients.Ten Hd patients were studied. Each patient underwent a block six sessions, then switched Hf. During the last session each dialytic treatment, continuous beat measurements systolic arterial pressure (SAP) heart rate (HR) performed. Spectral analysis variability...
Microcirculation (2010) 17, 271–280. doi: 10.1111/j.1549-8719.2010.00024.x Peritoneal dialysis (PD)-induced peritonitis leads to dysfunction of the peritoneal membrane. During peritonitis, neutrophils are recruited inflammation site by rolling along endothelium, adhesion, and transmigration through vessel walls. In a rat PD-model, long-term effects PD-fluids (PDF) on leukocyte-endothelium interactions neutrophil migration were studied under baseline inflammatory conditions. Rats received...
The most common kidney presentation in patients with multiple myeloma (MM) is acute injury (AKI) from cast nephropathy. Patients have a poorer 1 year survival compared to free of involvement. key treating nephropathy rapid reduction light chain (FLC) levels. modern era MM treatment was ushered by the introduction newer chemotherapeutic agents, such as bortezomib. Also, there interest application extracorporeal removal FLCs high cut-off hemodialysis (HCO-HD) using dialysis membrane higher...
<b><i>Introduction:</i></b> Impact assessment of new technologies in chronic hemodialysis (HD) is challenging due to HD patient frailty, the complexity clinical trials and practice variability among countries. Among most recent innovations, medium cut-off (MCO) dialyzers present an optimized membrane geometry that provides enhanced clearances for middle large molecular weight uremic toxins (UT). These are poorly cleared by available techniques largely contribute...
During the COVID-19 pandemic, psychological support was provided to healthcare workers in Nephrology and Dialysis Operative Unit of Azienda Ospedaliera Bassini using an EMDR group protocol decrease posttraumatic stress symptoms medium long term. The aim this study demonstrate effectiveness treatment reduce post-traumatic at end first pandemic wave its progress over time subsequent phases health emergency.The sample consisted 43 from Service who spontaneously decided take part Brief...