Is vision necessary for the development of categorical organization Ventral Occipito-Temporal Cortex (VOTC)? We used fMRI to characterize VOTC responses eight categories presented acoustically in sighted and early blind individuals, visually a separate group. observed that reliably encodes sound people using representational structure connectivity partially similar one found vision. Sound were, however, more encoded than group, format closer Crucially, represents membership sounds rather...

The occipital cortex of early blind individuals (EB) activates during speech processing, challenging the notion a hard-wired neurobiology language. But, at what stage processing do regions participate in EB? Here we demonstrate that parieto-occipital EB enhance their synchronization to acoustic fluctuations human theta-range (corresponding syllabic rate), irrespective intelligibility. Crucially, enhanced intelligibility was selectively observed primary visual EB, suggesting this region is...

Testing enhances memory more than studying. Although numerous studies have demonstrated the robustness of this classic effect, its neural and computational origin remains debated. Predictive learning is a potential mechanism behind phenomenon: Because predictions prediction errors (mismatch between feedback) can only be generated in testing (and not studying), benefit from predictive learning. We shed light on effect multi-level analysis perspective via combination cognitive neuroscience...

Recent studies have revealed that human position sense relies on a massively distorted representation of hand size and shape. By comparing the judged location landmarks an occluded hand, Longo Haggard (2010) constructed implicit perceptual maps represented structure, showing large underestimation finger length overestimation width. Here, we investigated contribution two potential sources distortions to such effects: reflecting spatial warping bodily tissue itself, perhaps somatotopic...

In humans, the occipital middle-temporal region (hMT + /V5) specializes in processing of visual motion, while planum temporale (hPT) auditory motion processing. It has been hypothesized that these regions might communicate directly to achieve fast and optimal exchange multisensory information. Here we investigated, for first time humans (male female), presence direct white matter connections between motion-selective using a combined fMRI diffusion MRI approach. We found evidence supporting...

The ability to compute the location and direction of sounds is a crucial perceptual skill efficiently interact with dynamic environments. How human brain implements spatial hearing is, however, poorly understood. In our study, we used fMRI characterize activity male female humans listening moving left, right, up, down as well static sounds. Whole-brain univariate results contrasting varying in their revealed robust functional preference for auditory motion bilateral planum temporale (hPT)....

The ventral occipito-temporal cortex (VOTC) reliably encodes auditory categories in people born blind using a representational structure partially similar to the one found vision (Mattioni et al.,2020). Here, combination of uni- and multivoxel analyses applied fMRI data, we extend our previous findings, comprehensively investigating how early late acquired blindness impact on cortical regions coding for deprived remaining senses. First, show enhanced univariate response sounds part occipital...

hMT⁺/V5 is a region in the middle occipitotemporal cortex that responds preferentially to visual motion sighted people. In cases of early deprivation, enhances its response moving sounds. Whether contains information about directions and whether functional enhancement observed blind specific, or also involves sound source location, remains unsolved. Moreover, impact this cross-modal reorganization on regions typically supporting auditory processing, like human planum temporale...

Abstract Speech is a multisensory signal that can be extracted from the voice and lips. Previous studies suggested occipital temporal regions encode both auditory visual speech features but their precise location nature remain unclear. We characterized brain activity using fMRI (in male female) to functionally individually define bilateral Fusiform Face Areas (FFA), left Visual Word Form Area (VWFA), an audio-visual region in Superior Temporal Sulcus (lSTS) control Para-hippocampal Place...

Early visual deprivation triggers enhanced representation of auditory information in the occipital cortex. How does this crossmodal plasticity mechanism impact on temporal cortex that typically involves similar coding? To address question, we used fMRI to characterize brain responses early blind (EB) and sighted control (SC) individuals listening sounds from four different categories (human, animal, objects places). Multivariate pattern analysis was decode these classes stimuli into...

In sighted individuals, a portion of the middle occipito-temporal cortex (hMT+/V5) responds preferentially to visual motion whereas planum temporale (PT) auditory motion. case early deprivation, hMT+/V5 enhances its response tuning toward moving sounds but impact blindness on PT remains elusive. Moreover, whether contains sound direction selectivity and reorganization observed in blind is specific or also involves localization equivocal. We used fMRI characterize brain activity individuals...

ABSTRACT In humans, the occipital middle-temporal region (hMT+/V5) specializes in processing of visual motion, while Planum Temporale (hPT) auditory motion processing. It has been hypothesized that these regions might communicate directly to achieve fast and optimal exchange multisensory information. this study, we investigated for first time humans existence direct white matter connections between motion-selective using a combined functional- diffusion-MRI approach. We found reliable...

How does experience shape the development of visual brain regions? We demonstrate that a transient period deprivation early in life humans leads to permanent alteration function cortex (EVC), while leaving categorical coding downstream ventral occipito-temporal (VOTC) mostly unaffected. used fMRI characterize response five categories (faces, bodies, objects, buildings and words) rare group cataract-reversal individuals who experienced blindness life, matched participants with typical...

Abstract The occipital cortex of early blind individuals (EB) activates during speech processing, challenging the notion a hard-wired neurobiology language. But, at what stage processing do regions participate in EB?Here we demonstrate that parieto-occipital EB enhance their synchronization to acoustic fluctuations human theta-range (corresponding syllabic rate), irrespective intelligibility. Crucially, enhanced intelligibility was selectively observed primary visual EB, suggesting this...

ABSTRACT The ability to compute the location and direction of sounds is a crucial perceptual skill efficiently interact with dynamic environments. How human brain implements spatial hearing however poorly understood. In our study, we used fMRI characterize activity male female humans listening left, right, up down moving as well static sounds. Whole univariate results contrasting varying in their revealed robust functional preference for auditory motion bilateral Planum Temporale (hPT)....

It has recently been proposed that some regions of the occipital cortex, typically considered purely visual, develop a preferential tuning for specific categories independently sensory input and visual experience. In contrast, several studies showed responses to non-visual inputs is unique blind individuals due crossmodal plasticity. To further assess how functional (in)dependent experience, we characterized with fMRI brain 8 presented acoustically in sighted early individuals, same stimuli...

Abstract Is vision necessary for the development of categorical organization Ventral Occipito-Temporal Cortex (VOTC)? We used fMRI to characterize VOTC responses eight categories presented acoustically in sighted and early blind individuals, visually a separate group. observed that reliably encodes sound people using representational structure connectivity partially similar one found vision. Sound were, however, more encoded than group, format closer Crucially, represents membership sounds...

Abstract How does blindness onset impact on the organization of cortical regions coding for deprived and remaining senses? We show that sound categories in occipital cortex is enhanced more stable within across blind individuals when compared to sighted controls, while a reverse group difference found temporal cortex. Importantly, share similar representational structure people, suggesting an interplay between reorganization following visual deprivation. suggest early, some extent late...