A5051770173- Colorectal Cancer Screening and Detection
- Radiomics and Machine Learning in Medical Imaging
- Cutaneous Melanoma Detection and Management
- Global Cancer Incidence and Screening
- Genital Health and Disease
- Cervical Cancer and HPV Research
- AI in cancer detection
- Nonmelanoma Skin Cancer Studies
- Cancer Risks and Factors
- Insect and Pesticide Research
- Acute Lymphoblastic Leukemia research
- Chromatin Remodeling and Cancer
- Advanced Graph Neural Networks
- Hydropower, Displacement, Environmental Impact
- Cerebral Palsy and Movement Disorders
- Artificial Intelligence in Healthcare
- Data Quality and Management
- Lung Cancer Treatments and Mutations
- Child Development and Digital Technology
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Acute Myeloid Leukemia Research
- Cutaneous lymphoproliferative disorders research
- Privacy-Preserving Technologies in Data
- Autism Spectrum Disorder Research
University of Lübeck
2015-2024
University of Copenhagen
2017
University Hospital Ulm
2017
Rigshospitalet
2017
University of Göttingen
2009
Darmstadt University of Applied Sciences
1997
We describe genetic and clinical characteristics of acute myeloid leukemia (AML) patients according to age from an academic population-based registry. Adult with newly diagnosed AML at 63 centers in Germany Austria were followed within the AMLSG BiO registry (NCT01252485). Between January 1, 2012, December 31, 2014, data 3525 (45% women) collected. The median was 65 years (range 18-94). comparison age-specific incidence rates epidemiological cancer registries revealed excellent coverage < 70...
Nonmelanoma skin cancer (NMSC) is the most common malignant neoplasm in Germany. However, little known about incidence trends of NMSC and its main subtypes basal cell carcinoma (BCC) squamous (SCC) Germany.Cancer registry data from fourteen German federal states was used to estimate age-standardized rates by histologic subtype. Annual percentage changes (APC) were estimated joinpoint regression models, order assess trend shifts years 1998 2010.In Germany, showed a significant increase 43.1...
Infection with human papillomavirus (HPV) is one of the more common sexually transmitted diseases in Germany. Vaccination against HPV was introduced Germany 2007. In this study, we sought to detect a population-based decline incidence cervical cancer women under age 30 who were eligible for vaccination first 11 years after its introduction.
Survival analysis based on cancer registry data is of paramount importance for monitoring the effectiveness health care. As new methods arise, compendium statistical tools applicable to grows. In recent years, machine learning approaches survival were developed. The aim this study compare model performance well established Cox regression and novel a previously unused dataset.
Patient-reported outcome measures (PROMs) and patient-reported experience (PREMs) are tools for assessing outcomes of experiences with health care from the patient's perspective. In Germany, PROMs widely used in research evaluating patient quality care. However, application PREMs is rather scant, especially oncology. The study aimed to assess feasibility patient-centred evaluation oncological Germany using German adaptation Danish National Cancer Patient Questionnaire. This questionnaire a...
Introduction: Survival analysis based on cancer registry data is of paramount importance for monitoring the effectiveness health care. As new methods arise, compendium statistical tools applicable to grows. In recent years, machine learning approaches survival were developed. The aim this study compare model performance well established Cox regression and novel approaches.Material Methods: lung from Schleswig-Holstein Cancer Registry.Four models are compared: Proportional Hazard Regression...
The aim of this study was (i) to update the reporting colorectal cancer survival differences over time in German-Danish border region (Schleswig-Holstein, Southern Denmark, and Zealand) (ii) assess extent which it can be explained by stage primary treatment. Incident invasive cases diagnosed from 2004 2016 with a follow-up vital status through 31 December 2017 were extracted registries. Analyses conducted anatomical subsite for four consecutive periods. Kaplan-Meier curves log-rank tests...
Zusammenfassung Hintergrund und Studienziele Nicht‐melanozytärer Hautkrebs (NMSC = nonmelanoma skin cancer) ist die häufigste Krebserkrankung in Deutschland. Allerdings herrscht weitgehende Unklarheit über Inzidenztrends des NMSC dessen Untertypen, Basalzellkarzinom (BCC) Plattenepithelkarzinom (SCC), Material Methoden Die Daten aus Krebsregistern von 14 deutschen Bundesländern wurden herangezogen, um altersstandardisierte Inzidenzraten nach histologischen Untertypen zu ermitteln. Anhand...
Abstract Background Generating synthetic patient data is crucial for medical research, but common approaches build up on black-box models which do not allow expert verification or intervention. We propose a highly available method enables generation from real records in privacy preserving and compliant fashion, interpretable allows Methods Our approach ties together two established tools informatics, namely OMOP as standard electronic health Synthea synthetization method. For this study,...
Vaccines against human papillomaviruses are covered by statutory health insurances in Germany since March 2007. A reduction of cervical and other HPV-associated cancers is expected. Incidence rates preceding the introduction vaccines unknown. These, however, important for assessing effects HPV vaccines. The aim present study was to bridge this knowledge gap.Based on cancer registry data from seven federal states, average yearly incidence cervical, anogenital, oropharyngeal oral cavity were...
Abstract The absolute configuration of 3‐methylpyrrolidine alkaloids isolated from the poison gland ants Leptothoracini was determined as (3 R ). enantiomeric separation by chiral gas chromatography and unambiguous structural assignment target compounds are described.