A5022654314- Clostridium difficile and Clostridium perfringens research
- Rabies epidemiology and control
- IgG4-Related and Inflammatory Diseases
- Nosocomial Infections in ICU
- Adipose Tissue and Metabolism
- Cardiovascular Disease and Adiposity
- Bartonella species infections research
- Liver Disease Diagnosis and Treatment
- Medical Practices and Rehabilitation
- Health and Medical Studies
- Venomous Animal Envenomation and Studies
- Sepsis Diagnosis and Treatment
- Cardiac Ischemia and Reperfusion
- Adipokines, Inflammation, and Metabolic Diseases
- Traditional Chinese Medicine Analysis
- Sirtuins and Resveratrol in Medicine
- Liver Diseases and Immunity
University of Freiburg
2019-2022
University Medical Center Freiburg
2020-2021
Impaired cardiac efficiency is a hallmark of diabetic cardiomyopathy in models type 2 diabetes. Adiponectin receptor 1 (AdipoR1) deficiency impairs non-diabetic mice, suggesting that hypoadiponectinemia diabetes may contribute to impaired due compromised AdipoR1 signaling. Thus, we investigated whether targeting adiponectin receptors improve function and energetics, attenuate mice.A non-selective agonist, AdipoRon, vehicle were injected intraperitoneally into Eight-week-old db/db or...
Zusammenfassung Procalcitonin (PCT) ist ein etablierter Marker für bakterielle Infektionen. Erhöhungen des PCT können jedoch aufgrund vielfältiger Ursachen auftreten und sind nicht spezifisch, wie wir in dem vorliegenden Fall kurz skizzieren möchten. Anamnese Wir berichten über eine 29-jährige Patientin, die bei unklaren abdominellen Schmerzen sowie seit 2 Tagen bestehender Übelkeit Erbrechen von der psychiatrischen Klinik vorgestellt wurde. Die war zunächst zielführend. Untersuchung...
Abstract Sirtuin 5 (SIRT5) is a mitochondrial NAD+-dependent protein deacylase which regulates the enzymatic activity of numerous proteins due to increased succinylation and malonylation, including enzymes energy substrate oxidation antioxidant enzymes. Since depletion oxidative stress contribute myocardial IR injury, it was our objective evaluate potential role SIRT5 in injury. In regular Langendorff heart perfusions, 8 week-old cardiomyocyte-selective SIRT5−/− mice showed no difference LV...
Autoimmune hepatitis is a rare but chronic autoimmune-mediated liver disease. Key features are elevated transaminases, hypergammaglobulinemia, presence of specific autoantibodies and typical histological features. Diagnostic scores helpful in establishing the diagnosis. Immunosuppressive therapy should be initiated every patient with inflammatory activity. First-line includes steroids azathioprine results biochemical remission majority patients. In most cases, lifelong required. Every...