Hyaluronan (HA) is a non-sulfated glycosaminoglycan that present in variety of body tissues and organs. has wide range biological activities are frequently influenced by molar mass; however, they also depend greatly on the source, purity, kind impurities hyaluronan. High-molar-mass HA anti-inflammatory, immunosuppressive, antiangiogenic properties, while low-molar-mass opposite properties. A number chemical modifications have been performed to enhance stability its applications medical...

D URING recent years significant advances have been made in using and development of biodegradable polymeric materials for life applications.Degradable biomaterials are preferred because these specific physical, chemical, biological, biomechanical degradation properties.Wide ranges natural or synthetic biopolymers capable undergoing hydrolytically enzymatically being investigated many applications.This review aimed to provide an overview the importance biomaterials, produced degraded...

Abstract The present study aimed to develop an efficient superabsorbent hydrogel for water conservation and slow release of Ethephon in sandy soil. Herein, carboxymethyl cellulose (CMC) was grafted via a free radical polymerization technique with acrylamide 2-Acrylamido-2-methylpropanesulfonic acid (AMPS) as hydrophilic monomers. developed CMC-g-(PAM-co-PAMPS) graft copolymer characterized by FTIR, TGA, SEM analysis prove the occurrence grafting process. Several factors affecting process...

Interpenetrating polymer network of cross-linked blend microspheres for controlled release Acebutolol HClP. Ramakrishna, B. Mallikarjuna, A. Chandra Babu, P. Sudhakar, K. Chowdoji Rao, M.C.S. Subha

Naringinase induced from the fermented broth of marine-derived fungus Aspergillus niger was immobilized into grafted gel beads, to obtain biocatalytically active beads. The support for enzyme immobilization characterized by ART-FTIR and TGA techniques. revealed a significant improvement in gel's thermal stability 200 300 °C. Optimization loading capacity increased gradually 28-fold 32 U/g 899 retaining 99 % efficiency 88 yield. process highly improved enzyme's 50 70 °C, which is favored food...

Glucoamylase enzyme is one of the most important enzymes. It catalyzes hydrolysis starch into soluble sugars. was covalently immobilized onto κ-carrageenan gel beads after activation by using polyethylenimine (PEI) followed glutaraldehyde (GA). All parameters in process were studied. The shows enhancement temperature profile as optimum for free 60 °C, and it becomes 60–80 °C that means broader range also stability acidic conditions more than enzyme. apparent Km enzyme, 147.46 mM, higher one,...

Bacillus subtilis strain-MK1 α-amylase was successfully immobilized on Chitosan-magnetic nanoparticles (Ch-MNP) that had been modified with polyethyleneimine (PEI) and glutaraldehyde (GA). Optimization of Ch-MNP/PEI/GA beads modification by Central Composite design enhanced the immobilization yield (IY %) 1.5-fold. characterized before after FTIR SEM. Ch-MNP/PEI/GA/Enzyme showed same pH optima free enzyme, while an elevation 10 °C in temperature observed its immobilization. displayed higher...

Abstract β-galactosidase has been immobilized onto novel alginate/tea waste gel beads (Alg/TW) via covalent binding. Alg/TW were subjected to chemical modification through amination with polyethyleneimine (PEI) followed by activation glutaraldehyde (GA). Chemical parameters including PEI concentration, pH, and GA concentration statistically optimized using Response Surface methodology (RSM) based on Box–Behnken Design (BBD). Analysis of variance (ANOVA) results confirmed the great...

Sagittal split osteotomy (SSO) is a routine procedure, but postoperative nerve disturbance (PNSD) remains challenge. This study aimed to perform medial horizontal (MHO) guided by ascending ramus geometry and avoid excessive deep dissection locate the lingula. The authors hypothesized that MHO would be located midway between 2 main reference points: subcoronoid (the point of concurrency an internal external oblique ridge mandible) at wideband retromolar trigon. SSO was performed on 40...

Abstract This article describes the covalent immobilization of penicillin G acylase (PGA) onto glutaraldehyde‐activated NH 2 ‐PVC membranes. The immobilized enzyme was used for 6‐aminopenicillanic acid production from hydrolysis. Parameters affecting process, which catalytic activity enzyme, such as concentration, immobilization's time and temperature were investigated. Enzyme concentration found determine effect. Higher obtained through performing at room temperature. Both optimum (35°C) pH...

“Lactose intolerance” is a medical problem for almost 70% of the world population. Milk and dairy products contain 5–10% w/v lactose. Hydrolysis lactose by immobilized lactase an industrial solution. In this work, we succeeded to increase loading capacity more than 3-fold 36.3 U/g gel using epoxy activated hydrogels compared 11 aldehyde carrageenan. The hydrogel’s mode interaction was proven FTIR, DSC, TGA. high activity group regarded its ability attach enzyme’s –SH, –NH, –OH groups,...

β -Galactosidase ( -gal) was immobilized by covalent binding on novel κ -carrageenan gel beads activated two-step method; the were soaked in polyethyleneimine followed glutaraldehyde. 2 full-factorial central composite experiment designs employed to optimize conditions for maximum enzyme loading efficiency. 11.443 U of enzyme/g achieved soaking 40 units with eight hours. Immobilization process increased pH from 4.5 5.5 and operational temperature 50 55°C compared free enzyme. The...

Novel grafted agar disks were prepared for the covalent immobilization of β-D-galactosidase (β-gal). The activated through reacting with ethylenediamine or different molecular weights Polyethyleneimine (PEI), followed by glutaraldehyde (GA). modification gel and binding enzyme verified Fourier Transform Infrared (FTIR) elemental analysis. Moreover, agar's activation process was optimized, amount immobilized increased 3.44 folds, from 38.1 to 131.2 U/g gel, during course optimization process....