- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Plant Disease Resistance and Genetics
- Vascular Procedures and Complications
- Platelet Disorders and Treatments
- Chromosomal and Genetic Variations
- Atrial Fibrillation Management and Outcomes
- Multiple Myeloma Research and Treatments
- Cancer therapeutics and mechanisms
- Heparin-Induced Thrombocytopenia and Thrombosis
- Plant and Fungal Interactions Research
- Intramuscular injections and effects
- Autoimmune and Inflammatory Disorders Research
- Genomics and Phylogenetic Studies
- Diagnosis and Treatment of Venous Diseases
- Blood groups and transfusion
- Blood Coagulation and Thrombosis Mechanisms
- Peripheral Neuropathies and Disorders
- Complement system in diseases
- Blood disorders and treatments
- Bone and Joint Diseases
- Hematopoietic Stem Cell Transplantation
- Cardiac tumors and thrombi
- Pharmacology and Obesity Treatment
- RNA Research and Splicing
Monash Health
2017-2023
Monash University
2020-2023
University of British Columbia
2018-2022
Monash Medical Centre
2017-2020
Canada's Michael Smith Genome Sciences Centre
2018
Alfred Health
2018
St Vincent's Hospital
2010
The University of Melbourne
2010
St. Vincent's Hospital
2010
There is limited data describing dexamethasone, cyclophosphamide, etoposide, and cisplatin (DCEP) in relapsed refractory multiple myeloma (RRMM). We reviewed 65 patients with RRMM receiving DCEP between 2005 2017 two Melbourne Hospitals. Patients had received a mean of three prior treatment lines (range, 1-11). The number cycles was 1-4). Overall response rate (ORR) 55% whilst 19% achieved MR SD. Median overall survival (OS) 9.6 months. Those bridged to autologous stem cell transplant (ASCT)...
In primary central nervous system lymphoma (PCNSL), venous thromboembolism (VTE) can cause significant morbidity and hinder chemotherapy delivery.
Peripherally inserted central catheter (PICC) thrombosis is common.To explore the prevalence of symptomatic PICC and pulmonary embolism (PE)/deep vein (DVT) in cancer non-cancer cohorts. In active cancer, we assessed Khorana risk score (KRS) Michigan (MRS) for predicting modifications to improve discriminative accuracy.We reviewed consecutive patients receiving chemotherapy through a April 2017 July 2018. For each case, identified contemporaneous control.Among 147 patients, median age 64...
Fingolimod is an oral sphingosine-1-phosphate receptor modulator which causes lymphocyte sequestration in lymph nodes and approved for relapsing multiple sclerosis. The Therapeutic Goods Administration of Australia aware only one case where fingolimod preceded immune thrombocytopenic purpura (ITP) by 5 weeks. Here we report three such cases. None were on any medications known to cause ITP routine investigations unremarkable. All cases treated with immunosuppression. Case 1 successfully...
Central venous access devices (CVADs) are commonly used in malignancies. We conducted an online, anonymous cross-sectional survey of practice regarding CVAD management haematology centres among clinicians Australia and New Zealand. identified variation clinical selection, insertion, removal. These findings highlight research gaps care.
Abstract Cannula provoked upper extremity superficial vein thrombophlebitis (UESVT) is common. Retrospective audit of 93 consecutive patients, 51% male, median age 57 years (range 20–91), with symptomatic UESVT revealed varied management including (37%), prophylactic (37%) and higher dose anticoagulation (27%). There was 2% (95% confidence interval (CI) 0–7.6) thrombus extension 1% CI 0–5.9) major bleeding, both limited to cancer. We argue unnecessary in most patients.