A series of tough polyion complex hydrogels is synthesized by sequential homopolymerization cationic and anionic monomers. Owing to the reversible interpolymer ionic bonding, materials are self-healable under ambient conditions with aid saline solution. Furthermore, self-glued bulk can be built from their microgels, which promising for 3D/4D printing additive manufacturing hydrogels. As a service our authors readers, this journal provides supporting information supplied authors. Such peer...

Recently, polyampolytes have been discovered to form hydrogels that possess high toughness, full resilience, and self-healing between two cut surfaces. The of this class is based on the re-forming multiple ionic bonds at fractured surfaces, in which mobility polymer segments strength play an important role. In work, we study effects healing temperature chemistry polyampholyte (chemical cross-linker density chemical structure monomers) kinetics efficiency. substantially accelerates kinetics....

Developing nonspecific, fast, and strong adhesives that can glue hydrogels biotissues substantially promotes the application of as biomaterials. Inspired by ubiquitous adhesiveness bacteria, it is reported neutral polyampholyte hydrogels, through their self-adjustable surface, show rapid, strong, reversible adhesion to charged biological tissues Coulombic interaction.

Recently, we have reported that polyampholytes, synthesized from free radical copolymerization of anionic monomer and cationic monomer, form physical hydrogels high toughness self-healing. The random distribution the opposite charges forms ionic bonds a wide strength. strong serve as permanent cross-links, imparting elasticity, whereas weak serves reversible sacrificial by breaking reforming to dissipate energy. In this work, focus on rupture behaviors polyampholyte hydrogel,...

Tough hydrogels with facile processability to reform into various shapes are required in many practical applications. In this work, we reported that a novel, tough, and self-healing physical hydrogel based on polyion complex (PIC) can be dissolved 4 M NaCl solution form PIC solution. The easily reprocessed shapes, such as thin films, sheets, fibers, capsules, by using simple methods, casting injection, while maintaining excellent mechanical properties comparable to, or even better than, the...

Oppositely charged homopolyelectrolytes were found to form strong, tough, and self-healing polyion-complex (PIC) hydrogels, similar polyampholytes (PA) which have opposite charges randomly distributed on the same polymer chains. The excellent mechanical performances of these two novel hydrogels are results dynamic ionic bonds formation between entangled For PIC system, only interchain bonding occurs, while for PA system both inter- intrachain exist. In addition, ion pairs expected stronger...

Our recent study has revealed that neutral polyampholytes form tough physical hydrogels above a critical concentration Cm,c by forming ionic bonds of wide strength distribution. In this work, we systematically investigate the behavior polyampholyte system, poly(NaSS-co-DMAEA-Q), randomly copolymerized from oppositely charged monomers, sodium p-styrenesulfonate (NaSS) and acryloyloxethyltrimethylammonium chloride (DMAEA-Q) without with slight chemical cross-linking. A phase diagram...

A series of N-substituted poly(Gly-alter-Val) peptides were successfully synthesized for the systematic evaluation micellization behavior alternating peptides. Three-component polymerization employing an aldehyde, a primary ammonium chloride, and potassium isocyanoacetate afforded four in excellent yields. We investigated dependence hydrophilic-lipophilic balance on behavior. All aqueous solutions exhibited upper critical solution temperature (UCST) behaviors, strongly indicating that binary...

A new species of fluorinated polymer surfactant was developed by three component polycondensation analogous to Ugi four-component condensation. The exhibited unique surface properties, which made cellulose-based materials hydrophobic and decreased the tension CHCl3. It turned out that forms micelles in

A series of alternating peptides with glycine-N-substituted valine dipeptide repeating units were synthesized. The N-substitution included methyl, ethyl, n-propyl, and hydroxyl groups. performance the polypeptides as kinetic hydrate inhibitors (KHIs) was evaluated in high pressure rocking cells a synthetic natural gas mixture using slow constant cooling method. All gave better KHI effect than low molecular weight poly(N-vinylpyrrolidone). polypeptide N-substituted n-propyl groups, PA-Pep,...

Abstract Three‐component polycondensation with an aldehyde, perfluoroalkylammonium triflate, and potassium isocyanoacetate produced amphiphilic fluorinated alternating peptides. The polymers work as a surfactant, which form associates in organic solvent. thermo‐dependent structures surface activity of the solvents were evaluated by results UV‐vis diffusion‐ordered NMR spectral measurements at various concentrations temperatures. It also turned out that regularly aligned bulky substituents...

A bolaamphiphile is a special member of amphiphilic molecules, which contains hydrophobic skeleton and two water-soluble groups on both ends. Bolaamphiphiles form thermally stable associates in water under lower concentration than those typical monoheaded amphiphiles, indicating the potential usefulness bolaamphiphiles as component nanomaterials. However, structural diversity limited at this moment. We recently developed synthesis quercetin-3-O-polyglycoside (QP) new entry via one-pot...

Abstract A facile approach to synthesize nature‐mimetic polypeptides via the formation of N ‐protected intermediates is developed. The based on use stable and easily cleavable ‐(1‐ p ‐methoxyphenethyl) (MPE) group as a new ‐protecting for an amide group. MPE‐protected are prepared in one‐pot three‐component polycondensation using amino acid–free starting materials. Subsequent acidic treatment obtained result perfect removal MPE give consisting alternating peptide skeleton. aqueous solutions...

An alternating peptide comprising phenyl glycine as a repeating unit skeleton shows strong, tough, and repeatable adhesion originating from its viscoelastic properties microfibril formation.

Quercetin polyglycoside as a new bolaamphiphile is prepared via one-pot grafting polymerization technique using sugar-based cyclic sulfite. Micelles comprising quercetin exhibit special pH-effects, in which the moieties on surface of micelle serve steric protecting group to endow chemical stabilization.

Abstract The development of new peptide‐based glues has been strongly urged from the viewpoints industrial applications and biomedical engineering. However, large‐scale synthesis polypeptides with an ordered sequence is highly challenging, which strictly restricts materials resources for research polypeptides. In this work, framework adhesive alternating peptides designed to be glycine (Gly)‐ N ‐substituted valine (Val) as dipeptide repeating sequence, considering peptapeptide viscoelastic...

Polysaccharide is a naturally abundant material, which regarded as an indispensable scaffold for structural material. The properties of polysaccharides are dependent not only on the structure repeating sugar unit but also glycosidic position between units. Herein, we report development polysaccharide-based self-standing film consisting occurring (1 → 2)-glucopyranan skeleton. derivative with hexyl carbamate groups Uret-Glcp(1,2) found to be highly stretchable and tough, exhibits maximum...

This paper describes the bolaamphiphilic properties of naturally occurring quercetin glycosides such as (Que), isoquercitrin (IQ), and polyglycoside (QP). The effects sugar chain length on micellization behaviors are discussed through time-course UV-vis spectra, profiles dynamic light scattering analyses, morphology micelles. It is indicated that polysaccharide chains integrated surface micelle would serve a steric protecting group to afford kinetically stable Quercetin new bolaamphiphile...

α-Galactosyl ceramide (GalCer) is an anticancer glycolipid consisting of d-galactose and phytosphingosine-based ceramide. Although the amphiphilic structure GalCer expected to form self-associates in water, self-assembly behaviors its derivatives have not been systematically investigated at this moment spite great importance. The evaluation morphologies properties associates should open new insights into chemistry such as application a nanocarrier elucidation detailed pharmacological...

Shear-induced adhesion of benzylated (1→2)-glucopyranan is attributed to the kinetically stabilized elongated structure and switchable projection hydroxyl groups induced by stress.