A5046334714- Total Knee Arthroplasty Outcomes
- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Bone and Joint Diseases
- Bone health and treatments
- Osteoarthritis Treatment and Mechanisms
- Diabetic Foot Ulcer Assessment and Management
- Lower Extremity Biomechanics and Pathologies
- Skin Diseases and Diabetes
- Knee injuries and reconstruction techniques
- Cellular and Composite Structures
- Bone Metabolism and Diseases
- Shoulder Injury and Treatment
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Oral microbiology and periodontitis research
- Bone Tissue Engineering Materials
- Nutrition and Health in Aging
- Advanced Glycation End Products research
- Calcium Carbonate Crystallization and Inhibition
Hospital for Special Surgery
2022-2025
Cornell University
2020-2021
Materials Science & Engineering
2021
Individuals with type 2 diabetes mellitus (T2DM) have a greater risk of bone fracture compared those normal glucose tolerance (NGT). In contrast, individuals impaired (IGT) lower or similar fracture. Our objective was to understand how progressive glycemic derangement affects advanced glycation endproduct (AGE) content, composition, and mechanical properties iliac from postmenopausal women NGT (n = 35, age 65 ± 7 years, HbA1c 5.8% 0.3%), IGT 26, 64 5 6.0% 0.4%), T2DM on insulin 25, 6 9.1%...
The ability to utilize magnetic resonance imaging (MRI) assess bony fixation may allow a better understanding of implant design and longevity. A new cementless total knee arthroplasty (TKA) was introduced, we hypothesized that this system would show similar compared cemented as assessed by multispectral MRI.Multiacquisition variable-resonance image combination selective MRI performed in 20 patients implanted with TKA. matched control group who had TKA also evaluated. Each patellar, femoral,...
Individuals with type 2 diabetes mellitus (T2DM) have an increased risk of fragility fracture despite exhibiting normal to high bone mineral density (BMD). Conditions arising from T2DM, such as reduced turnover and alterations in microarchitecture, may contribute skeletal by influencing morphology microdamage accumulation. The objectives this study were (i) characterize the effect T2DM on quantity cancellous bone, (ii) relate accumulation microarchitecture. Cancellous specimens femoral neck...
Abstract The infrapatellar fat pad (IPFP) has been implicated as a source of postoperative knee pain. Imaging the IPFP is challenging in patients with total arthroplasty (TKA) due to metallic susceptibility artifact. Multi‐Acquisition Variable‐Resonance Image Combination (MAVRIC)‐based T2 Mapping developed mitigate this artifact and can generate quantitative data. Objectives study were (1) measure values TKAs using MAVRIC based mapping technique (2) determine if are related degree scarring...
T2 mapping with GRAPPATINI, a combination of MARTINI (model-based reduction) and GRAPPA (parallel imaging reconstruction), was applied to routine knee evaluations compared quantitatively standard accelerated only GRAPPA. Regions articular cartilage, infrapatellar fat pad, muscle were analyzed. GRAPPATINI faster by ~2.2x provided similar values in most regions except for the pad femoral trochlea cartilage. This technique may facilitate incorporation quantitative retrospective studies...
The relative accuracy of an ultrashort echo time (UTE) based T1ρ sequence was compared to a MAPSS in the evaluation articular cartilage. Scanning with similar parameters between acquisitions performed, producing values all cartilage sub-compartments except for femoral trochlea (TrF). TrF MAPSS-T1ρ were shorter than UTE-T1ρ (10.91% difference, p = 0.0028). Overall, there reasonable agreement two sequences indicating that may be promising method use place conventional quantify
Micromotion at interfaces in modular total hip arthroplasties (THAs) induces corrosion and generation of adverse local tissue reactions (ALTRs), potentially leading to premature failure. The flexural rigidities (FR) THA femoral stem trunnions retrieved from revision surgery were correlated with MRI metrics histopathological outcomes. Increased FR was associated osteolysis a reduced synovial response, while lower granulomas, different synovitis types, necrosis. These results indicate that can...
Motivation: Anterior cruciate ligament (ACL) injury is associated with development of posttraumatic osteoarthritis and infrapatellar fat pad (IPFP) abnormalities. Goal(s): Our goal was to quantify texture features the IPFP in patients ACL (pre- post-ACLR) compare healthy contralateral knees. Approach: Image were calculated from bilateral knee MRIs acquired at baseline (TP0), 6-months post-ACLR (TP1), 1-year (TP2) acute, unilateral tears. Results: The ACL-injured knees had greater variability...
The infrapatellar fat pad (IPFP) has been implicated as a source of pain after total knee arthroplasty (TKA), but regions close to metallic implants are susceptible metal artifacts in MRI. Multi-acquisition variable-resonance image combination (MAVRIC) based T2 mapping technique can mitigate these artifacts. goal this study was evaluate how values the IPFP vary with degree scarring. were shorter and displayed wider range for individuals more severe MAVRIC may be used quantitative biomarker
Advances in additive manufacturing techniques have enabled the development of micro-architectured materials displaying a combination low-density and lightweight structures with high specific strength toughness. The mechanical performance can be assessed using standard techniques; however, when studying low- ultralow density materials, characterization subject to experimental artifacts. Additionally, quantitative assessment comparisons microarchitectures distinct lattice patterns is not...