A5043817746- Masonry and Concrete Structural Analysis
- Seismic Performance and Analysis
- Structural Behavior of Reinforced Concrete
- Zeolite Catalysis and Synthesis
- Structural Engineering and Vibration Analysis
- Building materials and conservation
- Thermochemical Biomass Conversion Processes
- Structural Health Monitoring Techniques
- Structural Analysis of Composite Materials
- Catalytic Processes in Materials Science
- Structural Load-Bearing Analysis
- Structural Response to Dynamic Loads
- Catalysis and Hydrodesulfurization Studies
- Catalysts for Methane Reforming
- Phase Equilibria and Thermodynamics
- Catalysis and Oxidation Reactions
- Geotechnical Engineering and Underground Structures
- Carbon Dioxide Capture Technologies
- Civil and Structural Engineering Research
- Concrete Corrosion and Durability
- Catalysis for Biomass Conversion
- Innovative concrete reinforcement materials
- Carbon dioxide utilization in catalysis
- Recycling and Waste Management Techniques
- Structural Analysis and Optimization
University College London
2015-2025
Vertex Pharmaceuticals (United States)
2022-2024
Aristotle University of Thessaloniki
2014-2023
Queen Mary University of London
2023
Biochemical Society
2022
Egnatia Odos (Greece)
2021
University of Ioannina
2006-2020
Transnational Press London
2015-2020
Torrington Hospital
2020
Technological Educational Institute of Epirus
2009-2018
Purpose We report the 5-year analysis from phase III Dasatinib Versus Imatinib Study in Treatment-Naïve Chronic Myeloid Leukemia Patients (DASISION) trial, evaluating long-term efficacy and safety outcomes of patients with chronic myeloid leukemia (CML) (CP) treated dasatinib or imatinib. Methods newly diagnosed CML-CP were randomly assigned to receive 100 mg once daily (n = 259) imatinib 400 260). Results At time study closure, 61% 63% dasatinib- imatinib-treated remained on initial...
OBJECTIVE: The objective of this study was to evaluate short-term efficacy and safety aripiprazole in the treatment irritability children adolescents with autistic disorder who were manifesting behaviors such as tantrums, aggression, self-injurious behavior, or a combination these. METHODS: This 8-week, double-blind, randomized, placebo-controlled, parallel-group conducted (aged 6–17 years) disorder. Patients randomly assigned (1:1) flexibly dosed (target dosage: 5, 10, 15 mg/day) placebo....
Background BMS-927711 is a potent, selective, competitive human calcitonin gene-related peptide (CGRP) receptor antagonist that has shown in vivo efficacy without vasoconstrictor effect. The objective of the current study was to determine an effective and tolerable dose range for acute treatment migraine. Methods In this randomized, double-blind, placebo controlled, dose-ranging study, 885 patients were randomized using adaptive design one following groups: (10, 25, 75, 150, 300, or 600 mg);...
Persons with toxic gain-of-function variants in the gene encoding apolipoprotein L1 (APOL1) are at greater risk for development of rapidly progressive, proteinuric nephropathy. Despite known genetic cause, therapies targeting kidney disease persons two APOL1 (G1 or G2) lacking. Download a PDF Research Summary. We used tetracycline-inducible human embryonic (HEK293) cells to assess ability small-molecule compound, inaxaplin, inhibit channel function. An G2–homologous transgenic mouse model...
The catalytic degradation of high-density polyethylene to hydrocarbons was studied over different zeolites. product range typically between C3 and C15 hydrocarbons. Distinctive patterns distribution were found with zeolitic structures. Over large-pore ultrastable Y, β zeolites, alkanes the main products less alkenes aromatics only very small amounts cycloalkanes cycloalkenes. Medium-pore mordenite ZSM-5 gave significantly more olefins. In medium-pore zeolites secondary bimolecular reactions...
Plastics are abundant and have a high energy content making their use in applications attractive. This article presents review on plastic waste (PW) management by pyrolysis gasification, which two types of thermochemical conversion (TCC) techniques. The PW the application its converted products important steps toward reducing reliance fossil fuels, enhancing closed-loop recycling materials circular economy. presented herein also focuses product distribution yields with emphasis potential...
Abstract The magnitude M = 6‐5 Coalinga earthquake of 2 May 1983 caused intense ground shaking throughout the epicentral region. Unanchored cylindrical supported tanks located at six sites within this oil producing area were damaged; damages included elephant's foot buckling base three moderate sized tanks, joint rupture and top shell in one large old rivetted tank, bottom plate a relatively new welded tank damage to floating roofs 11 tanks. Also spilled over many secondary occurred pipe...
To investigate the efficacy and safety of intramuscular (IM) aripiprazole for treatment agitation in patients with bipolar I disorder, manic or mixed episodes. In total, 301 experiencing acute were randomized to IM 9.75 mg per injection (n = 78), 15 lorazepam 2 70), placebo 75) this double-blind multicenter study. Patients could receive up 3 injections over 24 hours. Primary measure was mean change Positive Negative Syndrome Scale Excited Component score from baseline at hours after first...
Evaluate the long-term safety and tolerability of aripiprazole in treatment irritability pediatric subjects (6-17 years) with autistic disorder.A 52-week, open-label, flexibly dosed (2-15 mg/d) study outpatients a DSM-IV-TR diagnosis disorder who either had completed 1 2 antecedent, 8-week randomized trials or were enrolled de novo (ie, not treated trials). Safety measures included incidences adverse events, extrapyramidal symptoms, weight, metabolic measures, vital signs, other clinical...
Purpose Dasatinib is a potent BCR-ABL inhibitor with proven efficacy in adults newly diagnosed chronic myeloid leukemia (CML) phase (CP) and imatinib-resistant/intolerant disease. This I study of the Innovative Therapies for Children Cancer Consortium assessed dasatinib safety pediatric patients. Patients Methods Escalating once-daily doses (60 to 120 mg/m 2 ) were administered children (n = 58) (i) imatinib-pretreated CML or Philadelphia chromosome (Ph)–positive acute lymhoblastic (ALL)...