A5071160646- Metabolism, Diabetes, and Cancer
- Thyroid Cancer Diagnosis and Treatment
- Cervical and Thoracic Myelopathy
- Diet, Metabolism, and Disease
- Cardiovascular Function and Risk Factors
- Nanoplatforms for cancer theranostics
- Immunotherapy and Immune Responses
- Liver Disease Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Food Quality and Safety Studies
- S100 Proteins and Annexins
- Mitochondrial Function and Pathology
- Pancreatic function and diabetes
- Spinal Hematomas and Complications
- Cancer Immunotherapy and Biomarkers
- Currency Recognition and Detection
- Stock Market Forecasting Methods
- Probiotics and Fermented Foods
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Neuropeptides and Animal Physiology
- Phagocytosis and Immune Regulation
- Energy Load and Power Forecasting
- Trauma and Emergency Care Studies
- Pharmacological Receptor Mechanisms and Effects
- Spinal Cord Injury Research
Tianjin Medical University General Hospital
2024-2025
China Pharmaceutical University
2023
Shenzhen Second People's Hospital
2021-2023
Shenzhen University Health Science Center
2021-2023
Shenzhen Institutes of Advanced Technology
2022-2023
Shenzhen University
2022
Guangzhou Medical University
2022
Harbin Medical University
2017-2021
Second Affiliated Hospital of Harbin Medical University
2017-2021
Nanchang University
2012
Spinal cord injury (SCI) is a globally prevalent neurological condition, often resulting in motor, sensory, and autonomic dysfunctions that lead to permanent disability. However, outdated epidemiological data hinder the development implementation of effective public health policies. This study aimed examine compare trends burden spinal injury-specifically incidence, prevalence, years lived with disability (YLD)-in China worldwide from 1990 2021, project these over next 15 years. analyzed...
Objective: To explore the effect of cartilage oligomeric matrix protein (COMP) on papillary thyroid carcinoma (PTC).Methods: COMP expression levels in PTC tissues and matched adjacent normal were measured using tissue microarrays.Human cells cultured transduced with lentiviral short hairpin RNA against (COMP-shRNA), a negative control (NC) shRNA, or mock transfected (Control).We used Cell Counting Kit-8, performed colony formation assays, wound healing Transwell invasion flow cytometry,...
Diabetes mellitus complicated with heart failure has high mortality and morbidity, but no reliable diagnoses treatments are available. This study aimed to develop verify a new model nomogram based on clinical parameters predict diastolic cardiac dysfunction in patients Type 2 diabetes (T2DM).
Spinal Cord Injury (SCI) is a debilitating disease associated with significant economic burden owing to its high level of disability; however, current treatment options have only limited efficacy. Past research has shown that iron-dependent programmed cell death, also known as ferroptosis, plays critical role in the pathogenesis SCI. The sigma-1 receptor (Sig-1R) widely distributed central nervous system, and been implicated pathophysiology several neurological psychiatric disorders. Several...
Diabetic cardiomyopathy (DCM) is one of the most essential cardiovascular complications in diabetic patients associated with glucose and lipid metabolism disorder, fibrosis, oxidative stress, inflammation cardiomyocytes. Despite increasing research on molecular pathogenesis DCM, it still unclear whether metabolic pathways alterations are probably involved development DCM. This study aims to characterize metabolites DCM identify relationship between their biological processes or states...
The Graves' disease is an autoimmune highly associated with thyroid cancer, which extrathymic complication inflammatory ophthalmopathy called (GO). GO caused by orbital fat formation and extraocular muscle fibrosis due to inflammation of the connective tissue. Controlling closely related prognosis GO. In our study, we created a mouse model, was subjected transcriptome sequencing muscles fibrotic mice, differentially expressed SRC genes found. Subsequently, selected primary cultured...
Calcium dobesilate (CaD) is used effectively in patients with diabetic microvascular disorder, retinopathy, and nephropathy. Here we sought to determine whether it has an effect on cardiomyocytes calcium mishandling that characteristic of cardiomyopathy. Cardiomyocytes were sterile isolated cultured from 1 3 days neonatal rats treated vehicle (Control), 25 mM glucose+300 μM Palmitic acid (HG+PA), 100 CaD (CaD), or HG+PA+CaD test the effects signaling (Ca 2+ sparks, transients, SR loads)...
Introduction: The paper addresses the challenging problem of predicting short-term realized volatility Bitcoin price using order flow information. inherent stochastic nature and anti-persistence pose difficulties in accurate prediction. Methods: To address this, we propose a method that transforms data over fixed time interval (snapshots) into images. includes trade sizes, directions, limit book, is mapped image colour channels. These images are then used to train both simple 3-layer...
Papillary thyroid carcinoma (PTC) is a common tumor in endocrine system with unclear pathogenesis. The study has shown that the stimulation of cell growth, differentiation and gene mutation factors act together on gland cells to transform into from normal cells. A variety oncogenes suppressor genes are involved development PTC. In recent years, found BRAF close relationship pathogenesis prognosis Mutated affects occurrence PTC owing regulation by RAS protein kinase application biological...
Low response rate of immune checkpoint blockade (ICB)-based immunotherapy has limited its clinic application. The therapeutic cancer vaccine is a novel strategy to elicit robust responses synergize with ICB-based treatments via an enhancement and normalization strategy. Herein, this designed combination was realized by combining nano-vaccines whole tumor cell lysates/CpG liposomes (LCLs) anti-PD-L1 loaded lipid gel (anti-PD-L1@LG). Among these, LCLs were fabricated cationic the gels (LGs)...
Type 2 diabetes mellitus (T2DM), a worldwide disease that affects the quality of human life and social development. Glucose, fructose 1,5-anhydroglucitol are closely related to mellitus. However, few methods have been reported achieve these three carbohydrates in blood simultaneously. In this study, UPLC-MS/MS method allowing quantify glucose, fructose, simultaneously plasma was developed. The analysis performed by system with HILIC column. This new provided satisfactory results terms...
Abstract objective Existing studies have confirmed that both high triglyceride(TG) and non-density lipoprotein cholesterol(Non-HDL-c) are often closely linked with diabetes or insulin resistance. However, there no large prospective cohort discussed the connection between TG/non-HDL-c ratio incident type 2 diabetes. Therefore, using data from a representative of Chinese population, we conducted retrospective study to explore relationship TG/ non-HDL-c incidence Method We did study....