A5001674041- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Bariatric Surgery and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Birth, Development, and Health
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Breastfeeding Practices and Influences
- Diabetes Management and Research
- Diabetes Management and Education
- Healthcare professionals’ stress and burnout
- Diabetes and associated disorders
- Hemoglobinopathies and Related Disorders
- Obesity and Health Practices
- Lipoproteins and Cardiovascular Health
- Cardiovascular Health and Risk Factors
- Schizophrenia research and treatment
- Maternal and fetal healthcare
- Hepatitis Viruses Studies and Epidemiology
- Cardiovascular Function and Risk Factors
- Innovations in Medical Education
- Social Issues and Policies
- Clinical practice guidelines implementation
- Travel-related health issues
- Wound Healing and Treatments
- Blood transfusion and management
Ollscoil na Gaillimhe – University of Galway
2014-2023
University Hospital Galway
2005-2021
RMIT University
2013
National University of Ireland
2013
Clinical Science Institute
2012
OBJECTIVE A prospective study of the impact obesity on pregnancy outcome in glucose-tolerant women. RESEARCH DESIGN AND METHODS The Irish Atlantic Diabetes Pregnancy network advocates universal screening for gestational diabetes. Women with normoglycemia and a recorded booking BMI were included. Maternal infant outcomes correlated are reported. RESULTS total 2,329 women fulfilled criteria. Caesarean deliveries increased overweight (OW) (odds ratio 1.57 [95% CI 1.24-1.98]) obese (OB) (2.65...
Women who have diabetes mellitus during pregnancy are at higher risk of adverse outcomes. Excessive gestational weight gain (GWG) is also emerging as a factor for maternofetal complications, and in 2009, the Institute Medicine published recommendations appropriate GWG. It unclear whether excessive GWG confers additional to women with applicable this population.The objective study was examine pregnancies complicated by associated obstetric outcomes.This an observational study.The conducted...
Gestational diabetes (GDM) is associated with adverse fetal and maternal outcomes, identifies women at risk of future type 2 mellitus (T2DM). Breast-feeding may improve post partum glucose tolerance. Our objective was to identify the prevalence dysglycemia after GDM, delineate factors examine effect lactation on tolerance.We compared 75 g oral tolerance test (OGTT) results from 300 GDM 220 controls normal gestational (NGT) in five regional centers. data collected time OGTT. Methods Post OGTT...
The optimal screening regimen for gestational diabetes mellitus (GDM) remains controversial. Risk factors used in selective guidelines vary. Given that universal is not currently adopted our European population, we aimed to evaluate which strategies were most applicable.Between 2007 and 2009, 5,500 women universally screened GDM, a GDM prevalence of 12.4% using International Association Diabetes Pregnancy Study Groups (IADPSG) criteria was established. We retrospectively applied this...
Aims: This study examines the palliative care knowledge and attitudes towards caring for dying patient of nurses working in older people settings one rural region Ireland. Design: A cross-sectional survey design was used combining two questionnaires: quiz (PCQN) thanatophobia scale (TS). Results: total 61 completed questionnaire. There a significant correlation found between level (p=0.007), highlighting that as participants' increased, become more positive. While training did not impact on...
This is the first study to examine risk factors for diabetic foot ulceration in Irish general practice.To determine prevalence of established a community-based cohort, and explore potential estimated glomerular filtration rate (eGFR) act as novel factor.A prospective observational study.Patients with diabetes attending 12 (of 17) invited practices were screening. Validated clinical tests carried out at baseline assess vascular sensory impairment deformity. Ulcer incidence was ascertained by...
Raised maternal body mass index (BMI) in association with hyperglycemia is associated adverse pregnancy outcome. The contribution of raised BMI as an independent risk factor for outcome growing concern and increasing prevalence.The aim this study was to investigate the effects on glucose-tolerant women using International Association Diabetes Pregnancy Study Groups criteria.We studied a cohort glucose-tolerant, pregnant (n = 3656) who were attending antenatal obstetric clinics recruited...
In utero exposure to maternal antibodies targeting the fetal acetylcholine receptor isoform (fAChR) can impair movement, leading arthrogryposis multiplex congenita (AMC). Fetal AChR have also been implicated in apparently rare, milder myopathic presentations termed inactivation syndrome (FARIS). The full spectrum associated with fAChR is still poorly understood. Moreover, since some mothers no myasthenic symptoms, condition likely underreported, resulting failure implement effective...
Prospective evaluation of pregnancy outcomes in pregestational diabetes along the Atlantic seaboard 2006-2007.The Diabetes Pregnancy group, representing five antenatal centers a wide geographical location, was established 2005. All women with for >6 months before index were included. Results collected electronically via DIAMOND Information System. outcome compared background rates.There 104 singleton pregnancies. The stillbirth rate (25/1,000) 5 times, perinatal mortality 3.5 and congenital...
Diabetes in pregnancy imposes additional risks to both mother and infant. These increased are considered be primarily related glycaemic control which is monitored by means of glycated haemoglobin (HbA(1c)). The correlation HbA(1c) with clinical outcomes emphasises the need measure accurately, precisely for correct interpretation, comparison appropriately defined reference intervals. Since July 2010, assay Irish laboratories fully metrologically traceable IFCC standard. objective was...
Increases in serum triglyceride (TG) levels are associated with clinical response to clozapine treatment. Clozapine is the most efficacious therapy for treatment of refractory schizophrenia, although its use well recognised be substantial metabolic dysfunction. Interestingly, there some evidence that therapeutic benefit treatment-emergent weight gain and dyslipidaemia, specifically hypertriglyceridaemia. In this prospective observational study, we examine associations between 49 patients...
Background: Diabetes is a major chronic health condition. Prevalence rising, superseding public estimates. Chronic diseases are more common among lower socioeconomic groups, for example, the homeless population. There paucity of data on status population in Ireland, and prevalence diabetes associated cardiovascular risk factors unknown. Aim: We aimed to assess diabetes, pre-diabetes metabolic syndrome (MetS) an Irish regional Design: This study cross-sectional living university city Ireland....
Prospective evaluation of pregnancy outcomes in women with pregestational diabetes over 6 years.The ATLANTIC Diabetes Pregnancy group provides care for throughout pregnancy. In 2007, the identified that were poorly prepared and suboptimal. A change practice occurred, offering specialist-led, hub-and-spoke evidence-based care. We now compare from 2005 to 2007 those 2008 2010.There was an increase numbers attending preconception (28-52%, P = 0.01). Glycemic control before improved. There...
The purpose of this study was to examine the principal travel health priorities travellers. most frequently selected concerns were accessing medical care abroad, dying insect bites, malaria, personal safety and security threats. risks least concern culture shock, fear flying, jet lag sexually transmitted infections. This is first develop a hierarchy self-declared risk among
Recent studies implicate hyperglycemia as an important cause of macrovascular and ocular complications in diabetes mellitus. In this study, the authors examined effect high glucose on microvascular endothelial cell viability apoptosis culture. Human aortic cells (HAECs) human retinal (HRECs) were exposed to normal-glucose conditions (NG) high-glucose (NG supplemented with 25 mM D-glucose) for 72 h vitro. D-Mannitol was used osmotic control. Cell assessed by methlythiazolydiphenyltetrazolium...