A5040065192- Proteoglycans and glycosaminoglycans research
- Cell Adhesion Molecules Research
- Estrogen and related hormone effects
- Neonatal Respiratory Health Research
- Anatomy and Medical Technology
- Ethics and bioethics in healthcare
- Reproductive System and Pregnancy
- Osteoarthritis Treatment and Mechanisms
- Flowering Plant Growth and Cultivation
- Cancer, Lipids, and Metabolism
- Cardiovascular Health and Disease Prevention
- Sexual Differentiation and Disorders
- Endometriosis Research and Treatment
- Radiology practices and education
- Periodontal Regeneration and Treatments
- Cardiovascular and Diving-Related Complications
- Congenital Diaphragmatic Hernia Studies
- Plant and animal studies
- Renal and related cancers
- Urologic and reproductive health conditions
- Urological Disorders and Treatments
- Health Education and Validation
- Medical History and Research
- Sperm and Testicular Function
- High Altitude and Hypoxia
Universidad de Santiago de Chile
2012-2024
Universidad Bernardo O'Higgins
2020
Diego Portales University
2020
Universidad de Granada
2016-2018
Instituto de Investigación Biosanitaria de Granada
2016
The lung is formed from a bud that grows and divides in dichotomous way. A new growth center which determined by epithelial-mesenchymal interactions where proteins of the extracellular matrix (ECM) might be involved. To understand this protein participation during human development, we examined expression distribution proteoglycans relation to different types collagens period air conducting system installed. Using light microscopy immunohistochemistry evaluate (I, III VI) (decorin, biglycan...
The uterine tube (UT) is an important and complex organ of the women's reproductive system. In general, anatomy basic histology this are well-known. However, composition function extracellular matrix (ECM) UT still poorly understood. ECM a supramolecular material produced by cells which commonly restricted to basement membrane interstitial spaces. molecules play not only structural role, they also for cell growth, survival differentiation in all tissues. context, aim study was evaluate...
Abstract Vascularization and blood cell circulation are crucial steps during lung development. However, how vessels generated when is initiated still a matter of debate. A morpho‐functional analysis pulmonary vasculature was done using human samples between 31 56 days post‐fertilization (pf). The immunolocalization expression CD 31, 34, FLT ‐1, KDR the vascular growth factor ( VEGF ) were investigated. results showed that at day pf, capillary plexus already installed, few primitive...
The metabolite 2-methoxyestradiol (2ME) is an endogenous estrogen with potential therapeutic properties in reproductive cancers. However, the molecular mechanisms by which 2ME exerts its anticancer activity are not well elucidated. purpose of this study was to determine signals associated apoptotic effects a human endometrial cancer cell line. Ishikawa cells were treated non-apoptotic (0.1 µM) or concentrations (5 2ME, and 12 hours later mRNA levels for Scd2, Snx6, Spon1 determined real-time...
Introduction: Gestation under chronic hypoxia causes pulmonary hypertension, cardiovascular remodeling, and increased aortic stiffness in the offspring. To mitigate neonatal risk, pharmacological treatments (such as hemin sildenafil) have been proposed to improve vasodilation. However, little is known about effects of these on aorta. Therefore, we studied effect sildenafil aorta lambs gestated raised at highlands, thereby subjected hypoxia. Methods: Several biomechanical tests were conducted...
La falta de muestras biológicas humanas existentes, debido principalmente a las limitaciones ético-morales relacionadas con su obtención, ponen en relieve la necesidad buscar otras alternativas enseñanza y aprendizaje ciencias morfológicas. En este sentido, implementación lecciones través plataforma MOODLE proporciona oportunidad al estudiante interactuar un entorno que simula una situación propio del laboratorio tradicional. El objetivo presente trabajo fue generar lección sobre anatomía e...
RESUMEN : Wilhelm His (1831-1904) gran anatomista y embriólogo suizo, profesor de la cátedra anatomía Universidad Basilea Leipzig.His, realizó el primer intento estudiar los distintos estadios del embrión humano en su totalidad.Para tal fin, introdujo importantes avances tecnológicos que permitieron una comprensión más detallada humano, marcando un hito desarrollo embriología como ciencia.En este trabajo se resumen las principales contribuciones campo humana.Uno sus aportes fue invención...
The anti-implantation effects of high oestradiol (E2) concentrations could be mediated by E2 metabolites. Herein, we examined whether 2-methoxyoestradiol (2ME) impairs embryo implantation via its target protein F-spondin. Mice on Day 3 pregnancy were treated with concomitantly the cathecol-O-methyl transferase inhibitor OR486 and number implanted embryos was recorded 5 days later. effect 2ME or 4-methoxyoestradiol (4ME) also investigated. Plasma uterine levels measured 0.5, 1 3h after...
Las tubas uterinas (TU) son órganos tubulares fundamentales en la reproducción humana. No obstante, recién a mediados del siglo XVII con las investigaciones de Reinier De Graaf se comienza develar su verdadera función reproducción. En este trabajo resumen principales contribuciones Horacio Croxatto Avoni al conocimiento morfologÃa y fisiologÃa TU Sus aportes tienen relación transporte cigoto los gametos lo largo TU.
Tradicionalmente, la HistologÃa se ha apoyado del análisis de preparaciones histológicas a través microscopio para su enseñanza. En este sentido, uno los principales obstáculos que enfrentan estudiantes al analizar tejidos, es extrapolar una imagen bidimensional estructura tridimensional (3D). La impresión 3D permite subsanar esta limitación, haciendo posible fabricar material docente, con las caracterÃsticas requeridas un alto grado detalle y bajo costo. El objetivo trabajo fue...
In humans, even where millions of spermatozoa are deposited upon ejaculation in the vagina, only a few thousand enter uterine tube (UT). Sperm transiently adhere to epithelial cells lining isthmus reservoir, and this interaction is essential coordinating availability functional for fertilization. The binding UT epithelium (mucosa) occurs due interactions between cell-adhesion molecules on cell surfaces both sperm cell. However, there little information about involved. aim study was perform...
E-learning courses become increasingly important and relevant in medicine health sciences over the last decade. However, there are few teaching experiences of e-learning histology published literature worldwide. Moreover, most these studies focus on didactic aspects course without exploring student participation. The study presented below aimed to validate a scale measure participation an course. We provide evidence validity instrument based its internal structure for use with medical,...