Krishnendu Aich

ORCID: 0000-0001-8462-8206
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About
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Research Areas
  • Molecular Sensors and Ion Detection
  • Luminescence and Fluorescent Materials
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Analytical Chemistry and Sensors
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Crystallography and molecular interactions
  • Electrochemical Analysis and Applications
  • Sulfur Compounds in Biology
  • Photochromic and Fluorescence Chemistry
  • Crystal structures of chemical compounds
  • Synthesis and biological activity
  • Acne and Rosacea Treatments and Effects
  • Nitric Oxide and Endothelin Effects
  • Pesticide Exposure and Toxicity
  • Ovarian function and disorders
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Advanced Glycation End Products research
  • Nanoplatforms for cancer theranostics
  • Synthesis of Organic Compounds
  • Insect and Pesticide Research
  • Cardiac tumors and thrombi
  • Renal Transplantation Outcomes and Treatments

Indian Institute of Engineering Science and Technology, Shibpur
2011-2025

Jadavpur University
2016-2024

Chittaranjan National Cancer Institute
2024

Biogen (India)
2024

Hôpital Farhat Hached
2018-2022

Institute of Engineering Science
2014-2015

University of Burdwan
2013

A probe based on 2-(2′-hydroxyphenyl) benzothiazole (HBT) has been synthesized and used for the ratiometric detection of hydrazine. The is designed in such a way that excited state intramolecular proton transfer (ESIPT) HBT moiety gets blocked. chemodosimetric approach hydrazine to results recovery ESIPT by removal free through subsequent substitution, cyclization, elimination processes. successfully demonstrated enable live cells.

10.1021/ol4026759 article EN Organic Letters 2013-10-18

For ratiometric "naked eye" detection of CN(-), an ESIPT exhibiting benzothiazole receptor (BHI) is designed having one aldehyde group ortho and the other para to OH respectively. Due RAHBs, highly reactive undergoing nucleophilic cyanide addition selectively, which hampered ESIPT. This also supported by DFT TD-DFT calculations.

10.1039/c3cc39256b article EN Chemical Communications 2013-01-01

A spirobenzopyran-quinoline (SBPQ) based sensor was synthesized which selectively detects trivalent ions viz. Al3+, Fe3+ and Cr3+ through a fluorescence turn on signal in the red region (∼675 nm) with detection limit order of 10−8 M. The potentiality probe confirmed by employing it for bio-imaging Al3+ three different types live-cells.

10.1039/c3cc46860g article EN Chemical Communications 2013-01-01

In this study, we have synthesized a simple Schiff base type isophthaloyl salicylaldehyde hydrazone (ISH) moiety which selectively detects Al(III) and PPi with fluorescence enhancement at two different wavelengths in aqueous solution. The sensing phenomenon is also reversible thus the sensor beautifully mimics logic gates (INHIBIT EXOR gates).

10.1039/c3dt50621e article EN Dalton Transactions 2013-01-01

A new naphthalimide–quinoline based probe (NAQ) is designed and synthesized its structure confirmed through single crystal analysis. It detects the trivalent ions (Fe3+ or Al3+ Cr3+) selectively among other alkali transition metal studied. NAQ shows a distinct ratiometric fluorescence behavior upon addition of in CH3CN–HEPES buffer solution (40/60, v/v, pH = 7.4). This fluorogenic sensing to M3+ (M3+ Fe3+ can be observed by naked eye, when illuminated under UV light.

10.1039/c2ra22624c article EN RSC Advances 2012-12-18

A fluorescein based reactive probe has been designed and synthesized to detect hydrazine selectively over other common analytes. We used here 4-bromobutyrate as a masking unit of dye. Hydrazine plays the role de-masking agent set free dye through simultaneous substitution–cyclisation–elimination process. This leads 'turn on' fluorescence with easily discernible color change fast response time (<15 minutes).

10.1039/c3ra46663a article EN RSC Advances 2014-01-01

A new fluorescent probe was synthesized from rhodamine-6G and 6-(hydroxymethyl) picolinohydrazide for the sensing of Fe3+ in an aqueous environment. The structure sensor confirmed through its single crystal X-ray study. It exhibits a high specificity sensitivity towards over other interfering heavy transition metal ions (HTM). turn-on greenish-yellow fluorescence colorimetric change colourless to pink were observed upon addition which evokes almost 116- 23-fold enhancement absorbance...

10.1039/c3dt51974k article EN Dalton Transactions 2013-01-01

A new rhodamine–quinoline based dyad has been synthesized. It shows a highly selective response to Cd2+ in the presence of other competing metal ions aqueous media (pH = 7.1). The detection limit sensor is 10−7 M level.

10.1039/c3an36884j article EN The Analyst 2013-01-01

On the basis of Förster resonance energy transfer mechanism between rhodamine and quinoline–benzothiazole conjugated dyad, a new colorimetric as well fluorescence ratiometric probe was synthesized for selective detection Cd2+. The complex formation with Cd2+ confirmed through Cd2+-bound single-crystal structure. Capability imaging agent to detect cellular uptake demonstrated here using living RAW cells.

10.1021/acs.inorgchem.5b00784 article EN Inorganic Chemistry 2015-07-20

A new quinoline based sensor was developed and applied for the selective detection of Cd<sup>2+</sup> both <italic>in vitro</italic> vivo</italic>.

10.1039/c4dt02463j article EN Dalton Transactions 2015-01-01

We have synthesised a probe for the fluorescence ratiometric detection of Al<sup>3+</sup>. This can be used to image Al<sup>3+</sup> in living cells.

10.1039/c5nj01468a article EN New Journal of Chemistry 2015-01-01

A new spirobenzopyran derivative (SPNH) was designed and synthesized which applied in simultaneous colorimetric NIR fluorescence detections for Cr(3+). This receptor is normally colorless aqueous organic media but the formation of merocyanine occurs by Cr(3+) showing a yellow color. Here color UV-vis spectra strong emission at 675 nm makes SPNH good sensor ion. It also found to be useful cell imaging construction logic gate. shows INHIBIT gate OR absorption. To best our knowledge, this first...

10.1039/c3dt51851e article EN Dalton Transactions 2013-09-17

A new "naked-eye" and ratiometric fluorescent zinc sensor (TAQ) of carboxamidoquinoline with 2-chloro-N-(quinol-8-yl)-acetamide as a receptor was designed synthesized. The TAQ shows good water solubility high selectivity for sensing; about 15-fold increase in fluorescence quantum yield 100 nm red-shift emission upon binding Zn2+ aqueous HEPES buffer solution are observed. human lung cancer cell line (A549) activity is also demonstrated.

10.1039/c3an00067b article EN The Analyst 2013-01-01

A new chelator and ICT donor based visible light excitable Zn<sup>2+</sup>sensor was designed developed by integrating quinoline 2-hydroxy-3-(hydroxymethyl)-5-methylbenzaldehyde.

10.1039/c5ra03353e article EN RSC Advances 2015-01-01

Abstract A new visible‐light‐excitable fluorescence ratiometric probe for OCl − has been developed based on a triphenylamine‐diamiomaleonitrile (TAM) moiety. The structure of the dye was confirmed by single‐crystal X‐ray analysis. It behaves as highly selective and sensitive over other analytes with fast response time (∼100 s). reacts leading to formation corresponding aldehyde in mixed‐aqueous system. detection limit is 10 −8 M range. also exhibits solvatofluorochromism. Changing solvent...

10.1002/asia.201403234 article EN Chemistry - An Asian Journal 2015-01-21

A new benzothiazole–quinoline–rhodamine-6G-based probe was synthesised. The can exclusively detect Fe<sup>3+</sup> through a ratiometric manner in mixed aqueous system with detection limit the 10<sup>−8</sup> M range.

10.1039/c5nj03598h article EN New Journal of Chemistry 2016-01-01

A novel colorimetric and fluorescent sensing probe, CBTA, was designed for the selective detection of CN − .

10.1039/d3nj01157g article EN New Journal of Chemistry 2023-01-01

Expression of concern for ‘A rhodamine–quinoline based chemodosimeter capable recognising endogenous OCl − in human blood cells’ by Shyamaprosad Goswami et al. , RSC Adv. 2014, 4 24881–24886, https://doi.org/10.1039/C4RA03200D.

10.1039/d5ra90035b article EN cc-by RSC Advances 2025-01-01

A new chromogenic as well fluorogenic protocol based on the spirobenzopyran system for selective detection of nerve agent mimics (diethyl chlorophosphate or DCP vapour) within a few seconds (∼30 s) is designed, synthesized and characterized in this study.

10.1039/c5ra01216c article EN RSC Advances 2015-01-01
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