- Orthopaedic implants and arthroplasty
- Sarcoma Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Management of metastatic bone disease
- Shoulder Injury and Treatment
- Bone Tumor Diagnosis and Treatments
- Bone health and treatments
- Bone and Joint Diseases
- Total Knee Arthroplasty Outcomes
- Hip disorders and treatments
- Bone Metabolism and Diseases
- Musculoskeletal pain and rehabilitation
- Spinal Fractures and Fixation Techniques
- Orthopedic Infections and Treatments
- Bone health and osteoporosis research
- Oral and Maxillofacial Pathology
- Nerve Injury and Rehabilitation
- Cancer Diagnosis and Treatment
- Bone Tissue Engineering Materials
- Infectious Diseases and Tuberculosis
- Peripheral Nerve Disorders
- Shoulder and Clavicle Injuries
- Multiple Myeloma Research and Treatments
- Advanced materials and composites
- Titanium Alloys Microstructure and Properties
Campus Bio Medico University Hospital
2023-2024
Università Campus Bio-Medico
2010-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2004
University of Pavia
2004
Abstract Receptor activator of NFκB ligand (RANKL), RANK, and osteoprotegerin (OPG) represent the key regulators bone metabolism both in normal pathological conditions, including metastases. To our knowledge, no previous studies investigated compared RANK expression primary tumors metastases from same patient. We retrospectively examined by immunohistochemistry 74 tissues solid tumors, mostly breast, colorectal, renal, lung, prostate cancer. For 40 cases, tissue corresponding tumor was also...
// Marco Fioramonti 1, * , Daniele Santini Michele Iuliani 1 Giulia Ribelli Paolo Manca Nicola Papapietro 2 Filippo Spiezia Bruno Vincenzi Vincenzo Denaro Antonio Russo 3 Giuseppe Tonini Francesco Pantano Department of Medical Oncology, Campus Bio-Medico University Rome, Italy Orthopaedics and Trauma Surgery, Surgical, Oncological Oral Sciences, Section Palermo, These authors share first authorship are listed in alphabetical order Correspondence to: Iuliani, email: m.iuliani@unicampus.it...
Intervertebral disc degeneration (IVD) is a frequent pathological condition. Conservative management often fails, and patients with IVD may require surgical intervention. Several treatment strategies have been proposed, although only discectomy arthrodesis proved to be predictably effective. The aim of biological prevent manage degeneration, improve the function, anabolic reparative capabilities nucleus pulposus annulus fibrosus cells, inhibit matrix degradation. At present, clinical...
Spinal infections are an important clinical problem that often require aggressive medical therapy, and sometimes even surgery. Known risk factors advanced age, diabetes mellitus, rheumatoid arthritis, immunosuppression, alcoholism, long-term steroid use, concomitant infections, poly-trauma, malignant tumor, previous surgery or invasive procedures (discography, chemonucleolysis, surgical involving adjacent to the intervertebral disc space). The most common level of involvement is at lumbar...
In Brief Study Design. Posterior lumbar spine implants retrieved from patients affected by periprosthetic osteolysis were analyzed to identify corrosion and investigate the electromagnetic fields (EMF) generated currents their effect on human osteoblasts proliferation. Objective. Analysis of instrumentation better understand correlation this information with clinical factors. Summary Background Data. Recent studies have pointed out that mechanically assisted crevice represents initial...
The purpose of this article is to outline the current approach patients affected by metastasis spine and present a clinical surgical algorithm available for clinicians future research. A modern spinal in fact requires multidisciplinary contest where oncologists, radiotherapists, surgeons physical therapists cooperate with shared vision provide best possible integrated treatments available. authors constitute Bone Metastasis Study Group Italian Orthopaedic Society (SIOT): national group...
In Brief Study Design. Human osteoblast cultures were exposed to a very low intensity static magnetic fields (SMF) investigate its effects on growth and differentiation. Objective. Analysis of the periprosthetic SMF differentiation human cell in vitro. Summary Background Data. The pulsed electromagnetic (PEMF) proliferation, especially osteoblast-like cells is well described, whereas few data are available culture. We previously demonstrated that proliferation reduced when continuous...
Sciatic pain caused by endometriosis of the sciatic nerve is an uncommon clinical finding and seems to have been verified histologically in only a few cases. Patients complain typical signs symptoms common sciatica that are cyclic nature. Suggested compression lumbar root or its plexus could be confirmed electromyography, computed tomography, magnetic resonance imaging, prompt response hormonal suppression ovarian function with regression radiologic findings. often required radical surgery...
Introduction The role of unicompartmental knee arthroplasty (UKA) in spontaneous osteonecrosis the (SONK) is still controversial. Materials and methods We performed a systematic review to evaluate all available current literature on UKA setting SONK. A comprehensive electronic research was using PubMed, Embase, Web Science, Cochrane databases with keywords related SONK arthroplasty. Studies were selected predetermined inclusion criteria: 1) studies that specifically assessed treated UKA; 2)...