Exploiting specific interactions with titania (TiO2) has been proposed for the separation and recovery of a broad range biomolecules natural products, including therapeutic polyphenolic flavonoids which are susceptible to degradation, such as quercetin. Functionalizing mesoporous silica TiO2 many potential advantages over bulk an adsorbent robust synthetic approaches leading high surface area, stable platforms. Here, TiO2-surface-functionalized nanoparticles (MSNPs) synthesized characterized...

Titanium dioxide (TiO2) is a wide bandgap semiconductor that has range of applications including wastewater treatment, photocatalysis, solar cells, and sensors owing to its excellent electronic optical properties. However, the TiO2 (∼3.2 eV) along with recombination processes photoexcited charge carriers reduce interfacial transport properties respective activities. Energetics, response, corresponding photophysics excited can be altered through doping codoping composite formulation....

The chemistry and kinetics of NO removal by aqueous solutions sodium persulfate (Na2S2O8) simultaneously activated temperature Fe2+ were studied in a bubble reactor. Reaction pathways proposed mathematical model utilizing the pseudo-steady-state-approximation technique film theory mass transfer developed. was solved numerically using fourth order Runge–Kutta method Matlab to obtain species concentrations; correlate experimental data; estimate kinetic rate parameters. used investigate effects...

Abstract TiO 2 films of varying thicknesses (up to ≈1.0 µm) with vertically oriented, accessible 7–9 nm nanopores are synthesized using an evaporation‐induced self‐assembly layer‐by‐layer technique. The hypothesis behind the approach is that epitaxial alignment hydrophobic blocks surfactant templates induces a consistent, mesophase orientation across multilayer film, ultimately leading continuous, aligned pore channels. Characterization grazing incidence X‐ray scattering, scanning electron...

Amine-functionalized mesoporous silica nanoparticles (MSNPAs) are ideal carriers for oligonucleotides gene delivery and RNA interference. This investigation examines the thermodynamic driving force of interactions double-stranded (ds) with MSNPAs as a function length (84 282 base pair) particle pore diameter (nonporous, 2.7, 4.3, 8.1 nm) using isothermal titration calorimetry, extending knowledge solution-based nucleic acid–polycation to confined in nanopores. Adsorption follows two-step...

Incorporation of lipid assemblies on the surface and within pores mesoporous silica particles provides for biomimetic approaches to analyte sensing separations using high area platforms. This work investigates effect pore confinement location diffusivity in spherical (SBAS) as a function nanopore diameters (nonporous, 3.0, 5.4, 9.1 nm), which span range thickness 1,2‐dipalmitoyl‐ sn ‐glycero‐3‐phosphocholine bilayer (≈4 nm). Large‐diameter SBAS are imaged with sufficient spatial resolution...

Abstract The drying behavior of different freshwater fishes (with/without scales) is investigated using a simple convective heated air dryer. Drying processes are analyzed to study the kinetics drying, shrinkage dependent variable effective diffusivity, heat and mass transport, energy aspect drying. Among kinetic models, Hasibuan–Daud Haghi–Angiz‐I models produce best fit for with scales Hii model produces fish without scales. Diffusion analysis performed based on simplified solution Fick's...

Successful strategies for the attachment of oligopeptides to mesoporous silica with pores large enough load biomolecules should utilize high surface area provide an accessible, protective environment. A two-step oligopeptide functionalization strategy is examined here using diazirine-based heterobifunctional linkers. Mesoporous nanoparticles (MSNPs) average pore diameter ~8 nm and ~730 m2/g were synthesized amine-functionalized. Tetrapeptides Gly-Gly-Gly-Gly (GGGG) Arg-Ser-Ser-Val (RSSV), a...

Abstract Redox probe transport through supported lipid bilayers and nanopore‐confined assemblies on silica thin films is examined using electrochemical impedance spectroscopy (EIS). These systems are emerging biomimetic separation sensor platforms. The ability to quantify the accessibility of pore structure mesoporous demonstrated, which essential for incorporation carriers into lipids selective solute transport. molecules with varying hydrophilicity used compare ion in pore‐spanning...

Surfactant-templated mesoporous titania (TiO2) films have excellent physical and electronic properties, but some potential applications require thicker than the 100–200 nm typically prepared by sol–gel coating. Here, mechanism of forming micrometer thick TiO2 with vertically oriented nanopore channels a layer-by-layer deposition technique (up to eight 125 layers) is investigated. In situ grazing incidence small-angle X-ray scattering (GISAXS) performed on successive layers Pluronic...

Abstract Cellular uptake and expulsion mechanisms of engineered mesoporous silica nanoparticles (MSNPs) are important in their design for novel biomolecule isolation delivery applications such as nanoharvesting, defined using nanocarriers to transport isolate valuable therapeutics (secondary metabolites) out living plant organ cultures (e.g., hairy roots). Here, temperature‐dependent MSNP recovery processes roots examined a function surface chemistry. into time‐dependent quantified Ti...

Mesoporous structure development during calcination of titania-doped mesoporous silica thin films is characterized by in situ grazing-incidence small-angle X-ray scattering (GISAXS). Varying amounts titania (≤6 mol %) are incorporated cetyltrimethylammonium bromide (CTAB)-templated two methods this study: dispersion the matrix and fixing at pore surface complexation precursor with a sugar-based cosurfactant, dodecyl maltoside (C12G2). Before calcination, templated only CTAB display mixture...

The transport of two redox probes, 1,1′-ferrocenedimethanol (FDM, hydrophilic) and 1,1′-dioctadecyl-4,4′-bipyridinium dibromide (DBD, hydrophobic), through ionic liquid-filled and/or functionalized silica nanoporous thin films is compared as a function pore size (2.5 8 nm diameter pores). Electrochemical impedance spectroscopy (EIS) was used to measure the permeability these aqueous probes bare with pores containing physically confined liquid (IL, 1-butyl-3-methylimidazolium...

Nanoparticle delivery of polynucleic acids traditionally relies on the modulation surface interactions to achieve loading and release. This work investigates additional role confinement in mobility dsRNA (84 282 base pair (bp) sequences Spodoptera frugiperda) as a function silica nanopore size (nonporous, 3.9, 8.0, 11.3 nm). Amine-functionalized nanoporous microspheres (NPSMs, ∼10 μm) are used directly visualize exchange fluorescently labeled dsRNA. Porous particles fully accessible both...