A5080117878- Cancer Mechanisms and Therapy
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
- Nanoplatforms for cancer theranostics
- Ubiquitin and proteasome pathways
- RNA modifications and cancer
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
Jilin University
2022-2023
Union Hospital
2023
Union Hospital
2022
RING finger protein 187 (RNF187) belongs to domain-containing E3 ligases family, which was recently reported be involved in oncogenesis and development of several cancers. This research aims clarify the role RNF187 colorectal cancer (CRC) development.The expression miR-144-4p were determined by quantitative real-time polymerase chain reaction (qRT-PCR). The levels assessed western blot analysis. Cell Counting Kit-8 (CCK8) assay, clonogenic cell scratch test transwell assay used determine...
Extensive use of substances derived from natural sources has been documented in the treatment colorectal cancer (CRC). Lysionotin (Lys) is a flavonoid present flowers and leaves Gesneriaceae family plants. Despite its various pharmacological properties, which include neuroprotective, pro, antimalarial, anticancer effects, therapeutic advantages Lys for CRC remain uncertain. In this study, we demonstrated that successfully inhibited cell proliferation, migration, invasion HCT116 SW480 cells...