- Virus-based gene therapy research
- Protein purification and stability
- Radiopharmaceutical Chemistry and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Infant Development and Preterm Care
- Statistical Methods in Clinical Trials
- Hemophilia Treatment and Research
- Hepatitis B Virus Studies
- Immunotherapy and Immune Responses
- Neonatal Respiratory Health Research
- Platelet Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Pediatric health and respiratory diseases
- Pharmacogenetics and Drug Metabolism
- RNA Interference and Gene Delivery
- Molecular Biology Techniques and Applications
- Cystic Fibrosis Research Advances
- Neonatal and fetal brain pathology
- Work-Family Balance Challenges
- Blood Pressure and Hypertension Studies
- Clinical Laboratory Practices and Quality Control
- COVID-19 and healthcare impacts
- Surgical Simulation and Training
- Congenital Ear and Nasal Anomalies
- Stress and Burnout Research
Cedars-Sinai Medical Center
2005-2024
Sequoia Hospital
2017
University of Rochester Medical Center
2015
University of Rochester
2009
Baylor College of Medicine
2005-2007
University of Minnesota
2007
University of Toronto
2005-2007
University of California, Davis
2007
Federal Correctional Institution Schuylkill
2003
Pennsylvania State University
2003
Health-e-Access, a telemedicine service providing care for acute illnesses in children, has delivered >6500 visits from 10 primary practices Rochester, New York, by using access at 22 child and school sites. The goal was to assess the hypotheses that children served Health-e-Access received health more often but had fewer emergency department (ED) lower expenditures than did without through this service.By insurance claims, case study compared utilization (starting May 2001) of telemedicine,...
The 30-item Decision to Leave Scale (DLS) was developed with 631 college women and 420 in shelters. Seven DLS subscales emerged for concerns deciding stay or leave: Fear of Loneliness, Child Care Needs, Financial Problems, Social Embarrassment, Poor Support, Harm, Hopes Things Change. Mean internal reliability .73, mean test-retest .70. Discriminant validity demonstrated by expected associations between self-esteem, children, violence. Criterion greater shelters than women. Women violent...
To assess the hypothesis that effectiveness and safety of Health-e-Access telemedicine model for care children with special healthcare needs (CSHCN) acute illness equaled those in regular childcare schools (CRS).We examined use through insurance claims records spanning 5.7 7.3 years CSHCN CRS, respectively. Effectiveness was measured as visit completion, duplication, adverse events. Completed visits had diagnosis management decisions made, treatment implemented, based solely on telemedicine....
Expression of the immune-stimulatory molecule Fms-like tyrosine kinase 3 ligand (Flt3L) and conditional cytotoxic enzyme herpes simplex virus type 1 thymidine (HSV1-TK) provides long-term immune-mediated survival large glioblastoma multiforme (GBM) models in rodents. A limitation for predictive testing novel antiglioma therapies has been lack a glioma model animal. Dogs bearing spontaneous GBM may constitute an attractive large-animal GBM, which so far remained underappreciated. In...
Background: Chronic kidney disease (CKD) is a major public health concern in the United States with high prevalence, growing incidence, and serious adverse outcomes.
Plasma levels of 9-β-D-arabinofuranosyladenine-5′-phosphate (ara-AMP) and its metabolites 9-β-D-arabinofuranosyladenine (ara-A) 9-β-D-arabinofuranosylhypoxanthine (ara-Hx) were determined by high-performance liquid chromatography in four patients with chronic active hepatitis positive for B surface antigen eight severe herpesvirus infections normal liver function. Ara-AMP was given intravenously over a 3D-min period doses ranging from 10 to 30 mg ara-A equivalent/kg per day. The metabolism...
While women make up over 50% of students enrolled in medical school, disparities self-efficacy skills between men and have been observed throughout education. This difference is significant because low can impact learning, achievement, performance, thus create gender-confidence gaps. Simulation-based training (SBT) employs assessments self-efficacy, however, the Dunning-Kruger effect self-assessment posits that trainees often struggle to recognize their skill level. Additionally, gender on...
Digoxin pharmacokinetics were studied in 13 low-birth-weight infants requiring digoxin therapy. Their weights ranged from 820 to 2,710 g (mean = 1,440 g) and gestational ages 26 38 weeks 30.9 weeks). The distribution elimination of can be described by an open two-compartment model. Poor correlation between volume Vd beta 95.7 +/- 1.0 liters/kg) age (GA) or weight (Wt) was observed. half-life (47 21 h) inversely related GA Wt (r 0.69 0.66, respectively), but total body clearance (29.8 14.7...
Based on a common mechanism of action with gabapentin, we investigated the effects L-methionine hot flashes in postmenopausal women.After 1-week baseline period, 51 women experiencing at least five moderate-severe per day were randomized to one three groups 13:13:25 ratio: placebo/placebo, placebo/L-methionine, or L-methionine/L-methionine, respectively (phase 1/phase 2). Phase 1 was 12 weeks long, and phase 2 8 long. Participants took g PO BID either placebo. All participants also folate mg...
The vasodilative effects associated with the use of sodium acetate have been reported in literature. Preparations plasma protein fraction (PPF) substantially free this vasodilator were developed. This paper presents and discusses experimental work on improved product.
Pandemics create challenges for medical centers, which call innovative adaptations to care patients during the unusually high census, distribute stress and work hours among providers, reduce likelihood of transmission health workers, maximize resource utilization.We describe a multidisciplinary vascular access team's development improve frontline providers' workflow by placing central venous arterial catheters. Herein we development, organization, processes resulting in rapid formation...
Serial serum digoxin concentrations were measured over a 10-day period in 15 low birth weight infants requiring therapy. The calculated total body clearance (TBDC) was found to be highly dependent on gestational age and weight, with dose-normalized, steady-state inversely related the same factors. Because of decreased TBDC infants, our data support recent recommendations literature reduce maintenance doses these infants. Our study has further demonstrated that reduction should proportional...