A5058478633- Pancreatic function and diabetes
- Biochemical effects in animals
- Regulation of Appetite and Obesity
- Neuroendocrine regulation and behavior
- Diabetes and associated disorders
- Neuroscience of respiration and sleep
- Stress Responses and Cortisol
- Human Health and Disease
- Diet, Metabolism, and Disease
- Neurological Disorders and Treatments
- Industrial Engineering and Technologies
- Neuropeptides and Animal Physiology
- Oral microbiology and periodontitis research
- Circadian rhythm and melatonin
- Neurological Disease Mechanisms and Treatments
- High Altitude and Hypoxia
- Engineering and Environmental Studies
- Engineering Technology and Methodologies
- Heart Rate Variability and Autonomic Control
- Nitric Oxide and Endothelin Effects
- Adipose Tissue and Metabolism
- Religious, Philosophical, and Educational Studies
- Apelin-related biomedical research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Diverse Industrial Engineering Technologies
Institute of Scientific and Technical Information
2024
Zaporizhia State Medical and Pharmaceutical University
2002-2023
Vasyl' Stus Donetsk National University
2019-2022
Donetsk Institute for Physics and Engineering named after O.O. Galkin
2022
Siberian State Industrial University
2018-2021
Institute of Experimental Cardiology
2018
Zaporizhzhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine
1994
City Clinical Hospital No. 2
1929
City Hospital
1929
Kuban State Medical University
1929
THIS REPORT deals with a case of generalized xanthomatosis which exhibited an unusual feature—massive calcification the adrenals. Massive bilateral adrenal glands in early infancy is very rare finding, and few cases have been reported this lesion has discovered on plain x-ray picture vivo. OF CASE A 2-month-old girl was admitted to pediatric department Hadassah University Hospital March 12, 1954, from another hospital, diagnosis suspected acute abdomen. The infant had healthy gained weight...
Background. Posthypoxic cardiopathy is one of the risk factors for development cardiovascular pathology (rhythm disturbances, vascular dystonia, etc.) in subsequent age periods and requires treatment approaches. Objective. to evaluate cardioprotective effect modulators NO system by on ECG rats after intrauterine hypoxia. Methods. Modeling prenatal hypoxia (PH) daily intraperitoneal administration sodium nitrite solution pregnant female white weighing 220–240 g, aged 4.5 months, from 16th...
Abstract : In the complex treatment of chronic heart failure (CHF) β-adrenoblockers (carvedilol, nebivolol, bisoprolol, metoprolol) are used, which due to their pharmacological properties increase survival rate patients, improve cardio- and haemodynamic parameters, metabolism. However, modern realities in medicine require creation new more effective safe β-adrenoblockers. this regard, potential drug Hypertirl is interest. The aim was evaluate cardioprotective effect...
Introduction : Despite the success which was achieved in treatment of arterial hypertension, for optimization treatment, it is necessary to study pathogenesis primary hypertension and target organ damage on molecular level. Materials methods Our team studied mechanisms myocardial during metabolic disorders. We used spontaneously hypertensive rats (SHR) as an experimental model, and, additionally, we modeled diabetes mellitus atherosclerosis these rats. Results discussion obtained evidence a...
Modern biomedical research conducted in scientific laboratories is a basis not only for studying the pathogenetic mechanisms of diseases formation and progression, today they are widely used highly informative diagnostic methods development, new medicines creation, study newly developed pharmaceutical compounds influence on organism with their potential effectiveness assessment. The article highlights approaches possibilities functional state small laboratory animals assessing, taking into...
In modern medical science great attention is paid to the clarification of molecular mechanisms, which are basis adaptation environmental factors unusual origin and/or extraordinary strength. The aim study determine features a group genes with low expression level, associated hypoxia in pancreas Wistar rats under conditions intermittent hypoxia. Materials and methods. was conducted on 10 white, sexually mature rats, were divided into 2 groups (5 animals each). Animals 1 part control (intact)...
Mechanisms of beta-endocrinocyte differentiation involving c-kit may be associated with a number processes, including signaling pathways and regulatory mechanisms. Such factors as activation the pathway, an increase or decrease in cell proliferation survival, regulation gene programs stem cells are important controlling self-preservation regulating cellular types, that differentiated being impacted by intermittent hypoxic hypoxia, hypertension diabetes mellitus. The aim work is to determine...
The high growth rates of metallurgical production lead to an increase in the use mineral raw materials necessary for conducting processes. In almost all processing, crushed brittle material is required as a feedstock, obtained using crushing machines, which are also used process resulting products processing: slags, ferroalloys and others. design energy-efficient single-roll crusher with roll stop considered, destruction initial piece occurs due creation complex stress state mate-rial. such...
Today, diabetes mellitus (DM) represents a problem on which the attention of endocrinologists, general practitioners, and dentists is focused. Early pathological changes, manifest themselves in oral cavity, determine relevance social significance this pathology, because are usually first to diagnose disorders carbohydrate metabolism based results analysis specific complaints typical clinical symptoms damage mucous membrane periodontal tissues. The aim work find out pathogenetic...
The article describes the reason of additional dynamic forces occurrence in course operation lever mechanism jaw swivel drive with gaps hinges reducing reliability crushers operation. Gaps sampling mechanisms are equipped elastic pneumatic elements. These elements throughout entire cycle crank-beam constantly act on movable body an anti-friction liner mounted it. Mechanisms for provide a choice gap joints kinematic pairs, prevent appearance loads, and reduce level vibration mechanical...
The experiments show that hypoxia training leads to an increase of the immunoreactivity corticotropin and beta-endorphin content these neuropeptides. In this case, ratio area immunoreactive material corticotropin/beta-endorphin, coefficient their in PVN did not change significantly compared with control. Thus, selected mode adaptation, which is reflected balanced activity stress-realizing stress-limiting systems rats' hypothalamus.
Intermittent hypoxia affects a variety of pathological conditions in the body and is used medicine to reproduce sanogenic therapeutic effect. for clinical indications improve lung function; increase body’s adaptive capacity; obstructive sleep apnoea syndrome; anaemia, diabetes mellitus. In cancer radiotherapy, intermittent hypoxic training helps sensitivity tumour treatment. useful rehabilitation physical recovery patients after surgery or injury functional capabilities. However, date,...
The study aims to establish the appropriate parameters of UV excitation intensity and permanent time on pancreatic islets photobleaching, ratio useful signal in region interest nonspecific background fluorescence. Materials methods. pancreas three adult Wistar rats was fixed Bouin solution (20 hours) poured into paraplast after standard histological processing. carried out paraffin sections pancreas. islets’ insulin glucagon were determined by immunofluorescence method using monoclonal...
The neuroendocrine system occupies an important place in the systemic mechanisms of body response to stress. paraventricular nuclei hypothalamus (PVH) are one most links brain`s which determine reactivity hypothalamic-pituitary-adrenal axis (HPA) various stressors and thereby ensure development adaptive reactions by formation resistance stress.The aim research was study functional state peptidergic neurons medial parvocellular hypothalamic nucleus (PVHmp) during multi-day action intermittent...
Актуальность. Цель: изучение патогенетической роли нитрозативного и оксидативного стресса в возникновении анемии воспаления у детей раннего возраста. Материалы методы. Определяли содержание нитротирозина фосфолипазы А2 сыворотке крови 55 возраста (средний возраст — 1,6 ± 0,3 года) при помощи иммуноферментного анализа. Основную группу составили 30 с острыми бактериальными заболеваниями респираторного тракта, среди которых 21 пациента был диагностирован острый бактериальный бронхит 9...