A5078007283- Metabolomics and Mass Spectrometry Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Asthma and respiratory diseases
- Lipoproteins and Cardiovascular Health
- Advanced Chemical Sensor Technologies
- Diabetes Treatment and Management
- Respiratory and Cough-Related Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diet and metabolism studies
- Forensic Toxicology and Drug Analysis
- Computational Drug Discovery Methods
- Adipose Tissue and Metabolism
- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Pharmaceutical Practices and Patient Outcomes
- Clinical Nutrition and Gastroenterology
- Liver Disease Diagnosis and Treatment
- Synthesis of β-Lactam Compounds
- Phytochemical compounds biological activities
- Alcohol Consumption and Health Effects
- Identification and Quantification in Food
- Nosocomial Infections in ICU
- Advanced MRI Techniques and Applications
- Medication Adherence and Compliance
- Acute Myocardial Infarction Research
University of Malaya
2021-2025
Universiti Sains Malaysia
2015-2024
Federal Institute For Materials Research and Testing
2024
Hospital Seberang Jaya
2024
Hospital Sultanah Nur Zahirah
2024
University of Tabuk
2023
Ministry of Health
2023
University Malaya Medical Centre
2022
University of Manchester
2011-2016
Manchester Academic Health Science Centre
2011-2016
Incomplete childhood immunization against communicable diseases is a major concern and vaccine hesitancy remains hurdle to overcome in primary vaccination programs. This study was examine the parents' knowledge, awareness relation their children's status.A cross-sectional questionnaire design used. The parents who brought children for visit or follow-up at four public health clinics located Sandakan district were invited participate this survey. Informed consent obtained before each...
A relentless flood of information accompanied the novel coronavirus 2019 (COVID-19) pandemic. False news, conspiracy theories, and magical cures were shared with general public at an alarming rate, which may lead to increased anxiety stress levels associated debilitating consequences.To measure level COVID-19 overload (COVIO) assess association between COVIO sociodemographic characteristics among public.A cross-sectional online survey was conducted April May 2020 using a modified Cancer...
Breath volatile organic compounds (VOCs) may be useful for asthma diagnosis and phenotyping, identifying patients who could benefit from personalised therapeutic strategies. The authors aimed to identify specific patterns of breath VOCs in with clinically relevant disease phenotypes.Breath samples were analysed by gas chromatography-mass spectrometry. Asthma Control Questionnaire was completed, together lung function induced sputum cell counts. data reduced principal components, these...
Abstract Background Non-invasive phenotyping of chronic respiratory diseases would be highly beneficial in the personalised medicine future. Volatile organic compounds can measured exhaled breath and may produced or altered by disease processes. We investigated whether distinct patterns these were present obstructive pulmonary (COPD) clinically relevant phenotypes. Methods Breath samples from 39 COPD subjects 32 healthy controls collected analysed using gas chromatography time-of-flight mass...
Amphetamine-type stimulants (ATS), such as methamphetamine, amphetamine, and MDMA, are highly risky substances linked to neurochemical disruptions, metabolic disturbances, systemic toxicity. Despite substantial research on their neurotoxic effects, the pathways involved in ATS dependence remain poorly understood. This study aimed characterize signatures associated with using NMR-based metabolomics identify disruptions related chronic use. A cross-sectional was conducted involving 583...
Background Metabolomic profiling of exhaled breath condensate offers opportunities for the development noninvasive diagnostics in asthma. We aimed to determine and validate discriminatory metabolomic profiles adult asthma explore clinically relevant disease phenotypes. Methods Nuclear magnetic resonance spectroscopy was used analyse samples from 82 subjects with 35 healthy volunteers. Multivariate modelling performed on a 'training set' (70% total sample) order produce model classifying...
The most effective antiplatelet treatments for acute coronary syndrome (ACS) patients carrying CYP2C19 loss-of-function (LoF) alleles undergoing percutaneous intervention (PCI) is still debating and conflicting. It was aimed to compare the efficacy safety endpoints these treated with alternative P2Y12 receptor blockers (e.g. prasugrel or ticagrelor) against clopidogrel. Literature searched in PubMed, Cochrane library, Synapse 1000 Genomes databases following PRISMA guidelines identifying...
Substantial efforts are currently focused on investigating and developing new multidrug-resistant tuberculosis (MDR-TB) drugs diagnostic methods. In Yemen, however, the evaluation of health-related quality life (HRQoL) effect current MDR-TB treatment QoL commonly ignored. This study evaluated HRQoL during after identified risk factors that predictive score differences. A prospective cohort was conducted in four five main centres Yemen. The patients confirmed with completed SF-36 V2 survey at...
In the management of sepsis, providing adequate empiric antimicrobial therapy is one most important pillars sepsis management. Therefore, it to evaluate adequacy (EAMT) in patients admitted intensive care units (ICU) and identify determinants inadequate EAMT. The aim this study was ICU with or septic shock, data due shock two tertiary healthcare facilities Al-Madinah Al-Munawwarah were retrospectively reviewed. current used logistic regression analysis artificial neural network (ANN)...
Background: Hyperglycaemia (HG) during an acute ischemic stroke (AIS) is not only associated with unfavourable functional outcomes but also stroke-associated pneumonia (SAP). This study aimed to determine the prevalence of SAP among Malaysian patients AIS and predictors HG AIS. Methods: a retrospective cross-sectional that included admitted Hospital Sultanah Nur Zahirah, Malaysia from 2017 2020. was defined as infection first seven days after IS. blood glucose level > 7.8 mmol/L within 72...
Predicting the course of kidney disease in individuals with both type 1 and 2 diabetes mellitus (DM) is a significant clinical policy challenge. In several regions, DM now leading cause end-stage renal disease. The aim this study to identify modifiable non-modifiable risk factors, along markers coexisting conditions, that increase likelihood stage 3-5 chronic (CKD) development United Arab Emirates (UAE). This was single-center retrospective cohort based on data derived from electronic...