A5006141520- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Adrenal Hormones and Disorders
- Ophthalmology and Eye Disorders
- Infant Development and Preterm Care
- Maternal and Neonatal Healthcare
- Cancer, Hypoxia, and Metabolism
- Neonatal Respiratory Health Research
- Child and Adolescent Health
- Health and Medical Studies
- Glioma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Therapeutic Uses of Natural Elements
- Meningioma and schwannoma management
- Medical Imaging and Pathology Studies
- Electrolyte and hormonal disorders
- Family and Patient Care in Intensive Care Units
- Neurological and metabolic disorders
- Testicular diseases and treatments
- Neuropeptides and Animal Physiology
- Cerebrospinal fluid and hydrocephalus
- Thyroid Cancer Diagnosis and Treatment
- Vitamin K Research Studies
- Hydraulic flow and structures
Hospital Materno-Infantil
2022
Universitäres Kinderwunschzentrum Lübeck
2020
Southwest Bahia State University
2017
Hospital Universitario Puerta de Hierro Majadahonda
1991-2012
Universidad Autónoma de Madrid
1995-2012
University of Naples Federico II
2010
Sociedad Española de Endocrinología y Nutrición
2006
Bellvitge University Hospital
2006
Summary objective To develop a disease‐specific questionnaire suitable to measure health‐related quality of life (HRQOL) in acromegaly (ACROQOL). design, patients and measurements For the development ACROQOL different sources information were used: First, literature search was performed identify relevant papers describing impact HRQOL. Second, 10 endocrinologists identified main domains on HRQOL with acromegaly. Third, in‐depth, semistructured interviews conducted acromegalic items related...
Previous studies of preoperative pituitary function in patients with craniopharyngioma have been limited scope and focused on children. We evaluated the impact craniopharyngiomas their surgical treatment a large group mostly adult patients.We performed retrospective study treated at our centre between 1980 1992.Twenty-two men 13 women, most them adults, surgically for during above period.Serum glucose, GH, LH, FSH, TSH cortisol were measured both before after combined insulin induced...
OBJECTIVE While inferior petrosal sinus (IPS) sampling correctly diagnoses pituitary‐dependent Cushing's syndrome if a significant ratio of plasma ACTH between the IPS and peripheral blood is demonstrated, little has been said about significance negative in disease (e.g. false‐negative result). This study evaluates results patients with disease, compares them both imaging findings transsphenoidal examination. DESIGN The were retrospectively compared samples obtained before 2, 5 10 minutes...
There is concern that pegvisomant could be associated with a higher risk of tumor growth. The rate and possible determinants this growth are unknown.The objective the study was to investigate clinical, immunohistological, molecular factors conditioning in patients taking pegvisomant.This cross-sectional performed from 2004 2010 four university hospitals Spain.Seventy-five acromegalic active disease resistant somatostatin analogs treated were followed up for mean 29 ± 20 months.Magnetic...
ACTH-independent macronodular adrenal hyperplasia is a rare cause of Cushing's syndrome. Bilateral adrenalectomy considered the treatment choice, but patient obliged to receive lifetime steroid replacement therapy and susceptible insufficiency crisis. New therapeutic alternatives are being proposed as new etiopathological features disease known. Unilateral largest gland can be safe effective alternative, only short-term follow-up reported in literature. We present four consecutive patients...
Summary A 25 year old non-pregnant woman presented with a one-year history of amenorrhoea and polyuria. Three months before her admission, she had suffered lymphocytic meningitis. Hormonal studies revealed hypopituitarism central diabetes insipidus, associated primary autoimmune hypothyroidism. Computed tomographic scan magnetic resonance imaging showed pituitary mass suprasellar extension thickened stalk. Transsphenoidal surgery was performed the histological study fibrosis diffuse...
Summary Objective and design Depot somatostatin analogues are well accepted as either adjuvant or primary therapy for acromegaly, their long dosage intervals facilitate adherence to treatment. Our objective was evaluate whether lanreotide Autogel® 120 mg, every 4–8 weeks, effective in controlling acromegaly microparticles 30 1–2 weeks. Patients measurements who had used ≥ 2 months prestudy, responded treatment were recruited this open, prospective, multicentre phase III trial. Three five...
Summary Hypoparathyroidism secondary to Riedel’s thyroiditis is rare, only 2 previous cases having been reported. We present the case of a 36 year old woman with which developed into hypothyroidism and hypoparathyroidism.
Abstract. Fourteen adult patients (10 females and 4 males; age range 20-60 years) with persistent Cushing's disease after transsphenoidal microsurgery were treated pituitary irradiation. Supervoltage multiportal administration was employed at a total dose of 50 Gy (±0.65 sd ). The interval between irradiation less than 6 months in more 8. pituitary-adrenal axis evaluated postsurgically, before every thereafter. remaining anterior function simultaneously tested. Remission rates 12 24...
Summary A 39 year old man presented with gynaecomastia, loss of libido and high blood pressure. Hormone studies revealed elevated plasma levels oestradiol its precursors, which increased in response to adrenocorticotrophic hormone were reduced normal dexamethasone. Computed tomography disclosed a left adrenal mass surgery was performed. The removed tumour weighed 84 g the histological diagnosis adenoma. Nine years after surgery, he is asymptomatic, without hypertension, radiological or...
O objetivo foi caracterizar perfil e prevalência dos tipos de incontinência urinária em idosas avaliar sua qualidade vida pré- pós-programa treino fortalecimento da musculatura pélvica. Os métodos: Misto, intervencionista, a 11 mulheres com tal queixa, já cadastradas programa, atividade física regular. Consistiu sessões cinesioterapia para do assoalho pélvico, 3 meses, por semana, grupo, 50 minutos. Antes das sessões, aplicação três questionários: Gaudenz-Fragebogen, análise tipo...
We assessed anterior pituitary function in five patients with Cushing's syndrome before and after the removal of cortisol-secreting adrenal adenomas. Before surgery, all lacked response growth hormone to hypoglycaemia, four had low responses thyrotrophin releasing hormone, three hypogonadism two prolactin reserve. After successful adenoma, developed postoperative hypoadrenocorticism recovered impaired hormones within a period 3 months. Our results point direct inhibiting action...
Galanin is a 29-amino acid neuropeptide which stimulates the secretion of growth hormone (GH) in normal men. Although diagnosis acromegaly involves demonstrating hypersecretion GH and/or abnormalities secretory dynamics, sometimes it difficult to establish activity disease. The aim our study was assess response galanin infusion acromegalic patients (active and cured). We studied 19 subjects: 5 healthy volunteers (group I), 9 with active II), cured after transsphenoidal surgery III)....