A5045397634- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Facial Rejuvenation and Surgery Techniques
- Reconstructive Surgery and Microvascular Techniques
- Osteoarthritis Treatment and Mechanisms
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Cleft Lip and Palate Research
- 3D Printing in Biomedical Research
- Facial Nerve Paralysis Treatment and Research
- Dermatologic Treatments and Research
- Electrospun Nanofibers in Biomedical Applications
- Body Contouring and Surgery
- Wound Healing and Treatments
- Craniofacial Disorders and Treatments
- Obstructive Sleep Apnea Research
- Ophthalmology and Eye Disorders
- Orthopedic Infections and Treatments
- Surgical site infection prevention
- Collagen: Extraction and Characterization
- MicroRNA in disease regulation
- Silk-based biomaterials and applications
- Cancer Cells and Metastasis
- Consumer Perception and Purchasing Behavior
- Antimicrobial Peptides and Activities
Peking University
2016-2025
Peking University Third Hospital
2018-2025
Peking University First Hospital
2016
Abstract In the past few years, exosomes released from adipose-derived stem cells (abbreviated as ADSCs) have shown promises to provide therapeutic benefits in fields of regenerative medicine. miRNAs, existing exosomes, are endogenous, small noncoding RNAs that play important roles a variety cellular functions and tumor development. Emerging evidences indicated miR-21 is one miRNAs associated with angiogenesis. this study, we identified role ADSCs overexpressing regulating/promoting...
Three-dimensional cell-laden tissue engineering has become an extensive research direction. This study aimed to evaluate whether chondrocyte spheroids (chondro-spheroids) prepared using the hanging-drop method could develop better cell proliferation and morphology maintenance characteristics, be optimized as a micro unit for cartilage engineering. Chondro-spheroids were loaded into cross-linkable hybrid hydrogel of gelatin methacrylate (GelMA) hyaluronic acid (HAMA) in vivo vitro. Cell...
Type III recombinant humanized collagen (rhCol III) has a promising future in cosmetic applications. To investigate the histological changes associated with injection of different concentrations rhCol into dermis. Twenty mice were divided control, low-dose (LD) group, and high-dose (HD) group. The animals euthanized 1, 2, 3, 4 weeks after injection. Injections induced an increase formation concentration-dependent manner. I (Col I) was upregulated both HD LD groups to varying extents, often...
Trans-sutural Distraction Osteogenesis (TSDO) is a common surgical method for treating facial hypoplasia in secondary cleft lip and palate. Its mechanism involves utilizing mechanical traction to induce the differentiation of mesenchymal stem cells（MSCs） within into osteoblasts. Retinoic acid (RA) involved various life processes promotes osteogenic under low-dose conditions. However, impact RA treatment on cells force unclear. To investigate this mechanism, we performed cell stretching...
The incidence of vascular complications varies among different fillers. main purpose this study was to compare the risk embolism between PMMA (Artecoll) and hyaluronic acid (HA, Restylane) after artery injection. Rabbit ears were injected via central with 0.1 ml (group A), HA B), 0.2 C), or mL D), respectively. formation transparent emboli monitored right Tissue necrosis histopathological changes analyzed on day 7. With volume, dispersed within a few minutes only 5% had mild 7, while tended...
Osteoarthritis (OA) leads to the progressive degeneration of articular cartilage, yet there is currently no effective treatment available for both early and late stages osteoarthritis. Cartilage regeneration requires action prolonged retention multiple drugs at injured sites recruit endogenous cells facilitate cartilage formation. Here, we propose a cartilage-binding-peptide-modified lipid nanoparticle as drug carrier achieve sustained release protein (TGF-β3) small molecular (KGN) one...
To investigate the clinical application value of different flap transfer and repair techniques in adult patients with chronic osteomyelitis limbs complicated soft tissue defects. According to characteristics defects 21 cases, plastic surgery was applied, including debridement, negative pressure device, cover wound. Among cases local defect, 15 were repaired sural neurotrophic musculocutaneous transfer, 2 medial plantar skin ilioinguinal 1 patient z-forming wound, soleus muscle combined...
How to increase the long-term retention rate of autologous fat grafting has been widely discussed. This study aimed evaluate graft rates for most used processing methods in area facial esthetic surgery, including centrifugation, filtration, and sedimentation, using three-dimensional (3D) imaging.PubMed, Embase, Wiley/Cochrane Library, Web Science databases were comprehensively searched from inception July 2018 according guidelines American Society Plastic Surgeons Fat Graft Task Force...
Abstract Background Trans-sutural distraction osteogenesis (TSDO) involves the application of force to facial sutures stimulate osteogenesis. Gli1 + cells in cranial play an important role bone growth. However, whether differentiate into under is unknown. Methods 4-week-old Gli1ER/Td and C57BL/6 mice were used establish a TSDO model explore zygomaticomaxillary sutures. A cell lineage tracing was observe distribution remodeling. Results Distraction promoted remodeling during TSDO....
Abstract Background The mainstream facelifts in Western countries always involve the superficial fascia/superficial musculoaponeurotic system treatment. Meanwhile, subcutaneous face and neck lifts are widely applied among Asians. Objectives authors sought to evaluate outcomes of lift, including patient-reported 3-dimensional (3D) measurement outcomes, report on details surgical procedures. Methods Patients who received a lift from January 2017 June 2019 were asked complete FACE-Q scales,...