A5018667420- Heavy Metal Exposure and Toxicity
- Alzheimer's disease research and treatments
- Trace Elements in Health
- Mercury impact and mitigation studies
- Cholinesterase and Neurodegenerative Diseases
- Genetics and Neurodevelopmental Disorders
- Indigenous Studies and Ecology
- Nitric Oxide and Endothelin Effects
- Receptor Mechanisms and Signaling
- Aluminum toxicity and tolerance in plants and animals
- Health and Medical Research Impacts
- Eicosanoids and Hypertension Pharmacology
- Health, Environment, Cognitive Aging
- Ion channel regulation and function
- Effects and risks of endocrine disrupting chemicals
- Glutathione Transferases and Polymorphisms
- Phagocytosis and Immune Regulation
- Parkinson's Disease Mechanisms and Treatments
- Neurotransmitter Receptor Influence on Behavior
Autonomous University of Campeche
2017-2022
Center for Research and Advanced Studies of the National Polytechnic Institute
2014-2017
Instituto Politécnico Nacional
2017
University of Kentucky
2015
Levels of amyloid beta (Aβ) in the central nervous system are regulated by balance between its synthesis and degradation. Neprilysin (NEP) is associated with Alzheimer's disease (AD) ability to degrade Aβ. Some studies have involved exposure mercury (Hg) AD pathogenesis; therefore, our aim was investigate effects on anabolism catabolism Aβ differentiated SH-SY5Y cells incubated 1–20 μM Hg. Exposure 20 µM Hg induced an increase Aβ-42 secretion, but did not expression precursor protein (APP)....
ResumenLa expresión de nuestros genes está regulada por etiquetas químicas adheridas al ADN que indican cuándo deben ser prendidos o apagados.Cualquier alteración en este patrón etiquetas, especialmente durante etapas tempranas la vida como el embarazo neonatal, puede afectar génica y producir efectos indeseados inmediatos incluso muchas décadas después.Nuestras experiencias estilo vida, dieta contaminación pueden modificar químicas, lo más alarmante es algunos estudios sugieren los nocivos...