A5040533680- Catalytic Processes in Materials Science
- Advanced Chemical Physics Studies
- Inorganic Chemistry and Materials
- Nanocluster Synthesis and Applications
- nanoparticles nucleation surface interactions
- biodegradable polymer synthesis and properties
- Computational Drug Discovery Methods
- Vanadium and Halogenation Chemistry
- Nanoparticles: synthesis and applications
- Microplastics and Plastic Pollution
- Electron and X-Ray Spectroscopy Techniques
- Synthesis and biological activity
- Intestinal Malrotation and Obstruction Disorders
- Air Quality and Health Impacts
- Gastrointestinal disorders and treatments
- Advanced Electron Microscopy Techniques and Applications
- Advanced Materials Characterization Techniques
- Catalysis and Oxidation Reactions
- X-ray Diffraction in Crystallography
- Nanocomposite Films for Food Packaging
- Nanomaterials for catalytic reactions
- Sulfur Compounds in Biology
- Antimicrobial agents and applications
- Organoselenium and organotellurium chemistry
- Appendicitis Diagnosis and Management
University of California, Davis
2007-2024
Michigan State University
2021-2024
Saint-Gobain (United States)
2023-2024
University of Oxford
2021-2023
Symbiosis International University
2022-2023
National Institute of Pharmaceutical Education and Research
2014-2023
Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College
2022-2023
Gyeongsang National University
2021-2022
Indian Institute of Science Education and Research Pune
2016-2020
Sant Gadge Baba Amravati University
2020
This review of structurally simple and essentially molecular metal clusters on solid supports addresses synthesis, characterization, reactivity, catalysis. Examples supported made in high yields are Os3, Ir4, Ir6, Rh6, typical MgO, γ-Al2O3, zeolites. Supported synthesized by adsorption ligated clusters, deposition bare size-selected from the gas phase, complexes followed treatment to form clusters. Some have been imaged with atomic resolution. Reactions include ligand modifications,...
Owing to several mutations, the oncogene Kirsten rat sarcoma 2 viral homolog (KRAS) is activated in majority of cancers, and targeting it has been pharmacologically challenging. In this study, using an silico approach comprised pharmacophore modeling, molecular docking, dynamics simulations, potential KRAS G12D inhibitors were investigated. A ligand-based common feature model was generated identify framework necessary for effective inhibition. The chemical features selected two hydrogen bond...
AbstractIndiscriminate use of vanadium oxide nanoparticles (NPs) in steel industries and their release during combustion fossil fuels makes it essential to study toxic potential. Herein, we assessed the toxicological effects two types in-house synthesized NPs Wistar rats exposed through inhalation route. V2O5 VO2 exhibited rod spherical symmetry, respectively with a mean diameter 50 ± 20 30 10 nm. Assessment bronchoalveolar lavage fluid parameters demonstrated that NP-exposed animals had...
Twist1 is a basic helix-loop-helix transcription factor, essential during early development in mammals. While induces epithelial-to-mesenchymal transition (EMT), here we show that overexpression enhances nuclear and mitotic aberrations. This accompanied by an increase whole chromosomal copy number gains losses, underscoring the role of inducing instability (CIN) colorectal cancer cells. Array comparative genomic hybridization (array CGH) analysis further shows sub-chromosomal deletions,...
This study reports on using reactive extrusion (REX) modified thermoplastic starch particles as a bio-based and biodegradable nucleating agent to increase the rate of crystallization, percent crystallinity improve oxygen barrier properties while maintaining biodegradability PLA. Reactive blends maleated (MTPS) PLA were prepared ZSK-30 twin-screw extruder; 80% glycerol was grafted during preparation MTPS determined by soxhlet extraction with acetone. The found from 7.7% 28.6% 5% MTPS....
Metal atoms piggyback: Aberration-corrected STEM images of MgO-supported triosmium clusters show that the osmium reside atop magnesium (see picture). On basis results, structural models include metal–support interaction are derived.
Supported triosmium clusters, formed from Os3(CO)12 on MgO, were treated in helium at 548 K for 2 h, causing fragmentation of the cluster frame and formation mononuclear osmium dicarbonyls. The breakup resultant fragmented species characterized by infrared X-ray absorption spectroscopies, imaged scanning transmission electron microscopy. spectra identify surface complexes as Os(CO)2{Osupport}n (n = 3 or 4) (where braces denote support atoms). images show site-isolated Os atoms MgO. intensity...
Size, shape, nuclearity: Aberration-corrected scanning transmission electron microscopy was used to determine the 3D structures of MgO-supported Os3, Os4, Os5, and Os10 clusters, which have nearly matching those osmium carbonyl compounds with known crystal structures. The samples are among best-defined supported catalysts. As a service our authors readers, this journal provides supporting information supplied by authors. Such materials peer reviewed may be re-organized for online delivery,...
2-Methyl-3-[1-(N,N-dimethylamino)diazen-1-ium-1,2-diol-2-ato-methyl]-naphthalene-1,4-dione 1 (HyPR-1), a small molecule containing superoxide generator strategically linked to diazeniumdiolate-based nitric oxide donor, is reported. Evidence for HyPR-1's ability generate peroxynitrite in the presence of an enzyme as well enhance within cells provided. The utility this tool generating cellular studies demonstrated.
This paper reports on synthesis of modified thermoplastic starch (MTPS) and glycol-modified polyethylene terephthalate (PETG) blends in a twin-screw extruder. Scanning electron microscopy (SEM) images showed uniform, microdispersion MTPS PETG matrix, confirming compatibilization the blend by graft copolymers generated situ during reactive extrusion process. Incorporating 30% wt. gives biobased carbon content 22.8%, resulting reduced footprint removal 0.5 kg CO2 from environment/kg resin...
A novel method of determining nanocluster sizes and size distributions using high-angle annular dark-field imaging in scanning transmission electron microscopy is described. This demonstrated for MgO-supported [Os10C(CO)24]2- clusters formed by treating Os3(CO)12 precursors CO. The image analysis identified the presence both expected ratio (with matching those calculated on basis their crystallographically determined structures within 6%) also larger that can be readily as combinations...
The increasing use of Zinc Oxide nanoparticles (ZnONPs) in paint industry is not supplemented with adequate toxicology data. This report focuses on the fibrogenic toxicity caused due to co-exposure ZnONPs and toluene male Wistar rats, exposed for 28 days, through directed flow nose only exposure chamber. rats were grouped as air control, control (200 ppm), zinc oxide (10 mg/m3), low dose co-exposed (5 mg/m3 ZnO 200 ppm toluene) high toluene). Our study demonstrates that (as industry), even...
Abstract Z ‐contrast imaging in an aberration‐corrected scanning transmission electron microscope can be used to observe and quantify the sizes, shapes, compositions of metal frames supported mono‐, bi‐, multimetallic clusters even detect atoms single‐metal‐atom complexes, as well providing direct structural information characterizing metal–support interface. Herein, we assess major experimental challenges associated with obtaining atomic resolution images materials that are highly...
Initial steps of bimetallic Ru–Os cluster formation on MgO in the presence H2 are analyzed by EXAFS and IR spectroscopy. RuOs bond takes place after decarbonylation Ru3 clusters subsequently, at higher temperatures, Os3 to generate coordinative unsaturation (see scheme).
In this study, a solid masterbatch of starch–iodine complex with 6.7 wt.% iodine was prepared in pellet form using ZSK-30 twin-screw extruder. Thermogravimetric (TGA) and isothermal TGA analysis the pellets revealed that there no significant loss due to sublimation during reactive extrusion. These demonstrated antifungal properties when applied strawberries via dip coating an aqueous solution, extending their shelf life from two days eight days, thereby reducing fungal growth visual decay....
An increased number of screen failure patients in a clinical trial increases time and cost required for the recruitment. Assessment reasons can help reduce rates improve recruitment.We collected retrospective data human epidermal growth factor receptor (HER2) positive Indian breast cancer patients, who failed screening phase 3 trials ascertained their from logs. Statistical comparison was done to ascertain if there are any differences between private public sites.Of 727 screened at 14 sites,...
Abstract The structures of small, robust metal clusters on a solid support were determined by combination spectroscopic and microscopic methods: extended X‐ray absorption fine structure (EXAFS) spectroscopy, scanning transmission electron microscopy (STEM), aberration‐corrected STEM. samples synthesized from [Os 3 (CO) 12 ] MgO powder to provide supported intended be triosmium. results demonstrate that the are in absence oxidants. Conventional high‐angle annular dark‐field (HAADF) STEM...
Scientists all over the world are facing a challenging task of finding effective therapeutics for coronavirus disease (COVID-19). One fastest ways putative drug candidates is use computational discovery approaches. The purpose current study to retrieve natural compounds that have obeyed drug-like properties as potential inhibitors. Computational molecular modelling techniques were employed discover with SARS-CoV-2 inhibition properties. Accordingly, InterBioScreen (IBS) database was obtained...
Abstract Traditional ecological knowledge (TEK) or local (LEK) has only recently gained traction as “legitimate” science in Western academic discourse. Such approaches to inclusivity continue face institutional, sociocultural, and equity barriers being fully accepted discourse comparison Western-based frameworks. Postcolonial studies have attempted rectify this Western-domination characterizing diverse forms of bird–human relationships. However, the integration multiple cosmologies...
Widely used in global households, fenugreek is well known for its culinary and medicinal uses. The various reported properties of are by virtue the different natural phytochemicals present it. Regarded as a promising target, interleukin 2 receptor subunit alpha (IL2Rα) has been shown to influence immune responses. In research, using silico techniques, we have demonstrated potential IL2Rα binding three polyphenol stilbenes (desoxyrhaponticin, rhaponticin, rhapontigenin) from fenugreek. As...
Samples containing small, nearly uniform clusters of a heavy metal, Os, were prepared on high-area porous support consisting light atoms, MgO, to provide an opportunity for critical assessment estimates cluster size determined by extended X-ray absorption fine structure (EXAFS) spectroscopy and high-angle annular dark field scanning transmission electron microscopy (HAADF-STEM). Supported carbonyl approximated as decaosmium reductive carbonylation adsorbed Os3(CO)12 at 548 K 1 bar. Infrared...