A5000642644- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer Cells and Metastasis
- Polyomavirus and related diseases
- Acute Myeloid Leukemia Research
- Cardiac Imaging and Diagnostics
- 3D Printing in Biomedical Research
- Multiple and Secondary Primary Cancers
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- BRCA gene mutations in cancer
- Cardiac Valve Diseases and Treatments
- Advanced Breast Cancer Therapies
- Pathogenesis and Treatment of Hiccups
- Lung Cancer Research Studies
- Mesenchymal stem cell research
- Neuroendocrine Tumor Research Advances
- Anesthesia and Pain Management
- Molecular Biology Techniques and Applications
- Cancer Treatment and Pharmacology
- Cancer Diagnosis and Treatment
- PARP inhibition in cancer therapy
- Nausea and vomiting management
- Erythropoietin and Anemia Treatment
- Cardiac Ischemia and Reperfusion
Italian Society of Periodontology and Implantology
2023-2024
Study of the problem multiple primary malignant neoplasms (MPMNs) becomes more important and significant in modern clinical oncology. MPMN is a varied group independent tumors varying origin located one or several organs. Due to introduction single-use elastomeric microinfusion pumps into practice, continuous cyclical drug outpatient in-hospital treatment oncological patients with MPMNs can be performed. Significant successes specific therapy led increased lifespan MPMNs. Prolonged...
With the development of modern next generation sequencing based DNA diagnostic methods, it has become possible to study hereditary predisposition oncohematological diseases. Germline variants (mutations) RUNX1 , CEBPA GATA2 ANKRD26 DDX41 FANC - (Fanconi anemia), etc. genes, associated with hematological malignancies, have been identified. Timely diagnosis such diseases will allow for medical genetic counseling and testing patient’s relatives identify or exclude risk developing disease,...
About 15 % of lung tumors are small cell cancer. Because its extremely poor prognosis with a median overall survival 10 months, and the long absence new treatment options beyond combination platinum etoposide (EP), introduction immunotherapy has been significant development in this disease. IMpower133 was first phase III trial demonstrated statistically increase atezolizumab group from 10.3 to 12.3 months. Our clinical case demonstrates efficacy an EP atezolizumab. The patient got 6 courses...
Currently, nausea and vomiting during chemotherapy are a common adverse event affecting quality duration of life patients. Introduction several classes antiemetics correct use various medications in the form combination scheme prophylaxis allow to effectively control these events. However, incidence remains high clinical practice, according surveys doctors underestimate frequency complications This is primarily caused by patient noncompliance using for delayed prevention due complicated...
Treatment of patients with multiple primary malignant neoplasms caused by genetic mutations requires correct priorities from the clinician in selection most effective therapeutic tactics. An important aspect this case is identification neoplasm determining patient’s survival. The main goal to achieve maximal treatment effect for tumor and use therapy methods control other synchronous metachronous tumors. article presents a clinical patient BRCA1 mutation-associated recurrent ovarian cancer...
Oncological and cardiovascular diseases are the main causes of mortality worldwide. The rate these pathologies tends to increase as population ages. implementation highly effective therapeutic schemes has led a significant in survival oncology patients over last decades. In many cases, who underwent treatment is caused by events arising consequence aggressive antitumor or pre-existing chronic diseases. Among complications that developed both during active malignant neoplasm longer term,...
Сегодня результаты развития геномных технологий меняют подход к диагностике и лечению онкологических заболеваний. Так, клинические подходы профилактике, рака молочной железы сместились в сторону использования молекулярно-генетической иммуногистохимической информации. Целью настоящего обзора является описание возможностей применения различных молекулярно-генетических исследований опухолевой ткани с целью повышения эффективности лечения железы. В обзоре обсуждаются современных молекулярных...
Anemia is one of the most frequent manifestations oncological diseases and complications cytotoxic chemotherapy. Development this symptom directly associated with decreased quality life possible stimulation neoangiogenesis, increased tumor aggressiveness sensitivity to chemotherapy radiation. Current clinical trial data show overall survival patients anemia. Modern methods anemia correction in include exchange transfusion administration recombinant erythropoietins. Transfusion...