A5041231663- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- Advanced MRI Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Cardiovascular Function and Risk Factors
- Elasticity and Material Modeling
- Cardiac Imaging and Diagnostics
- Ultrasonics and Acoustic Wave Propagation
- Cardiovascular Disease and Adiposity
- Electrical and Bioimpedance Tomography
- Renal and Vascular Pathologies
- Optical Imaging and Spectroscopy Techniques
- Flow Measurement and Analysis
- Non-Invasive Vital Sign Monitoring
- Medical Imaging Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Vascular anomalies and interventions
- Vascular Procedures and Complications
Physique pour la médecine Paris
2019-2021
ESPCI Paris
2015-2020
Centre National de la Recherche Scientifique
2015-2020
Inserm
2015-2020
Université Paris Sciences et Lettres
2015-2020
ParisTech
2015-2020
Institut Langevin
2015-2018
Institut Jean Nicod
2016-2018
Hospitais da Universidade de Coimbra
2018
Université Paris Cité
2016-2017
The goal of our study was to investigate the potential myocardial shear wave imaging (SWI) quantify diastolic stiffness (MS) (kPa) noninvasively in adult healthy volunteers (HVs) and its physiological variation with age, hypertrophic cardiomyopathy (HCM) populations heart failure preserved ejection function (HFpEF).
Ultrasound localization microscopy can map blood vessels with a resolution much smaller than the wavelength by localizing microbubbles. The current implementations of technique are limited to 2-D planes or small fields view in 3-D. These suffer from minutelong acquisitions, out-of-plane microbubbles, and tissue motion. In this paper, we exploit recent development 4D ultrafast ultrasound imaging insonify an isotropic volume up 20000 times per second perform three dimensions. Specifically, 32...
We present herein 4D ultrafast ultrasound flow imaging, a novel ultrasound-based volumetric imaging technique for the quantitative mapping of blood flow. Complete distribution was achieved through 2D tilted plane-wave insonification, multi-angle cross-beam beamforming, and 3D vector Doppler velocity components estimation by least-squares fitting. performed in large fields view at very high volume rate (>4000 volumes s-1) using 1024-channel scanner matrix-array transducer. The precision...
Ultrafast imaging using plane or diverging waves has recently enabled new ultrasound modes with improved sensitivity and very high frame rates. Some of these modalities include shear wave elastography, ultrafast Doppler, contrast-enhanced functional imaging. Even though already encounters clinical success, increasing even more its penetration depth signal-to-noise ratio for dedicated applications would be valuable.
Transthoracic shear-wave elastography (SWE) of the myocardium remains very challenging due to poor quality transthoracic ultrafast imaging and presence clutter noise, jitter, phase aberration, ultrasound reverberation. Several approaches, such as diverging-wave coherent compounding or focused harmonic imaging, have been proposed improve quality. In this study, we introduce (UHCC), in which pulse-inverted diverging waves are emitted coherently compounded, show that an approach can be used...
The aim of this study was to investigate the potential coronary ultrafast Doppler angiography (CUDA), a novel vascular imaging technique based on ultrasound, image noninvasively with high sensitivity intramyocardial vasculature and quantify blood flow dynamics. Noninvasive techniques are currently limited observation epicardial arteries. However, many studies have highlighted importance microcirculation microvascular disease. CUDA performed in vivo open-chest procedures 9 swine. Ultrafast...
eHealth devices, including smartwatches and smart scales, have the potential to transform health care by enabling continuous, real-time monitoring of vital signs over extended periods. Existing technologies, however, lack comprehensive microvascular network, which is linked conditions such as diabetes, hypertension, small vessel diseases. This study introduces an ultrasound approach using a capacitive micromachined transducer row-column array for ultrasensitive three-dimensional (3D) Doppler...
Quantitative assessment of myocardial stiffness is crucial to understand and evaluate cardiac biomechanics function. Despite the recent progresses ultrasonic shear wave elastography, quantitative evaluation still remains a challenge because strong elastic anisotropy. In this paper we introduce smart ultrasound approach for non-invasive real-time quantification velocity (SWV) fractional anisotropy (FA) in locally transverse isotropic medium such as myocardium. The relies on simultaneous...
The heart's supply of oxygen and nutrients relies on the coronary vasculature, which branches from millimeter-sized arteries down to micrometer-sized capillaries. To date, imaging technologies can only detect large epicardial vessels, whereas intramural vasculature remains invisible due cardiac motion. We recently introduced ultrafast Doppler angiography, a noninvasive vascular technology based ultrasound that enables visualization in humans. In this letter we describe, using an open-chest...
Coronary flow rate remains complex to assess in clinical practice using non-invasive, non-ionizing imaging tools. In this study, we introduce 3D ultrafast Doppler coronary angiography (3D UDCA), an ultrasound-based method blood flows three-dimensions at high volume-rate and one single heartbeat. We demonstrate that UDCA can visualize the vasculature with temporal spatial resolution quantify absolute flow. The feasibility of technique was demonstrated open-chest swine model. left-anterior...
In this study, we propose 4D Ultrafast vector flow imaging, through the use of plane-wave ultrafast and cross-beam Doppler imaging in order to map in-vivo blood flows 3D, provide volumes complex fields at high frame rate, quantify volumetric rate accurately. was performed large field views volume rates (>4000 volumes/s) using a 1024-channel scanner 2D matrix-array probe. The accuracy precision technique evaluated in-vitro an artery phantom compared with industrial meter. Volumetric errors...
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Very high frame rate ultrasound imaging has enabled the development of novel modalities such as functional brain, cardiac electrophysiology, and quantitative real-time intrinsic mechanical properties tumors, to name a few. We present here extension Ultrafast Ultrasound Imaging in three dimensions based on use either diverging or plane waves emanating from sparse virtual array located behind probe. High contrast resolution were achieved while maintaining rates thousands volumes per second. A...
Introduction: In vivo neuronal activity imaging is key to understand the mechanisms of complex brain behavior. 2D Functional Ultrasound (fUS) Imaging a powerful tool for measuring activation with high spatiotemporal sampling (80μm, 1 ms) using neurovascular coupling. Here, we demonstrated proof concept in full 3-D fUS and extend research work toward 3D functional connectivity mice. Method: A fully programmable 1024-channel ultrasound platform was used drive 32 x matrix phased arrays (9 MHz...