A5086177342- Analytical Chemistry and Chromatography
- Complementary and Alternative Medicine Studies
- Analytical Methods in Pharmaceuticals
- Drug Solubulity and Delivery Systems
- Plant tissue culture and regeneration
- DNA and Nucleic Acid Chemistry
- Synthesis and Characterization of Heterocyclic Compounds
- Organophosphorus compounds synthesis
- Chemical Reaction Mechanisms
- Plant nutrient uptake and metabolism
- Gut microbiota and health
- Crystallization and Solubility Studies
- Tryptophan and brain disorders
- Biofuel production and bioconversion
- Bone health and treatments
- Metal complexes synthesis and properties
- Magnetism in coordination complexes
Kazakh-British Technical University
2022-2025
Morpholine derivatives play an important role in modern pharmaceutics due to their wide spectrum of biological activity. In this regard, the aim study is investigate properties new synthesized aminophosphonates based on morpholinoethylamine, including Aminophosphonates were by Kabachnik-Fields reaction, purified and characterized using IR NMR spectroscopy. Biological activity was studied vitro vivo: myelostimulating effect laboratory rats plant growth during treatment wheat seeds assessed....
Abstract Forming complexes with β-cyclodextrin can enhance stability, dissolution rate, solubility, and bioavailability of an active pharmaceutical ingredient. In this study, the inclusion behavior between (β-CD) diphenhydramine, clonidine, tolperisone in DMSO-d 6 was investigated using NMR spectroscopy. 1 H, 13 C, COSY, HMQC, ROESY data were applied to determine structure complexes, molecular docking analysis engaged identify most favorable host–guest interactions complexes. Complexation...
Herein we report on the synthesis of new ionic compounds based N-ethoxyethylpiperidine, trimecaine and piromecaine, obtained via N-alkylation with alkyl halides.The combination piperidine ring, secondary amine group, piromecaine in form a base different radicals bring to molecule biological activity and/or reduce toxic effects parent compounds.The potential pharmacological were predicted PASS online service (Prediction Activity Spectra for Substances) showing cardiotonic, antiarrhythmic...