- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Hypothalamic control of reproductive hormones
- Advanced Memory and Neural Computing
- Biochemical effects in animals
- Mitochondrial Function and Pathology
- Receptor Mechanisms and Signaling
- Anesthesia and Neurotoxicity Research
- EEG and Brain-Computer Interfaces
- Metabolomics and Mass Spectrometry Studies
- Neuroscience and Neural Engineering
- Circadian rhythm and melatonin
- Sexual Differentiation and Disorders
- Hormonal and reproductive studies
- Ion channel regulation and function
- Sexual function and dysfunction studies
- Nicotinic Acetylcholine Receptors Study
- Lipid Membrane Structure and Behavior
Institute of Evolutionary Physiology and Biochemistry
2023
Umeå University
2021
N. I. Lobachevsky State University of Nizhny Novgorod
2015-2021
Institute for Biomedicine
2021
Yaroslav-the-Wise Novgorod State University
2015
Na/K-ATPase maintains transmembrane ionic gradients and acts as a signal transducer when bound to endogenous cardiotonic steroids. At subnanomolar concentrations, ouabain induces neuroprotection against calcium overload apoptosis of neurons during excitotoxic stress. Here, the role lipid rafts in interactions between Na/K-ATPase, sodium–calcium exchanger (NCX), N-methy-D-aspartate receptors (NMDARs) was investigated. We analyzed 0.5–1-nanometer ouabain’s effects on responses miniature...
We present a novel integration technology for replacing damaged microcircuits in the rat brain with electronic neuronal networks. This will allow simulating important functions, such as memory, through adaptive stimulating effects of neural interfaces at cellular and network levels. The proposed system includes devices to register process signals adaptively stimulate areas according online algorithm decoding registered activity. stimulation is implemented hardware memristive connections that...
The aim of the investigation was to study astroglia functional activity in hippocampal slices rat at different postnatal development stages by modeling metabolic changes brain.Materials and Methods.The carried out on Wistar rats three age groups: days 5-10, 10-20, more than 20 animal using a calcium imaging method.Results.In early developmental stages, normal astroglial found require additional energy substrates.Changing brain state low temperature had no significant effect astrocyte all...
The aim of the study is to identify mechanisms mediating differences in sexual behavior between Sprague Dawley and Wistar rats, order choose optimal stock for research into pharmacological correction male dysfunction.The experiments were carried out on sexually mature rats two stocks (Sprague Wistar) weighing 350-450 g aged 3 6 months. comparative animal was performed using standard tests social interaction, locomotor activity, anxiety level, as well mating patterns. In determine role...